Nanomaterials in tumor immunotherapy: new strategies and challenges

Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)

Published: June 13, 2023

Abstract Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune responses of the body. It has become another important modality therapy with significant clinical efficacy advantages compared to chemotherapy, radiotherapy targeted therapy. Although various kinds tumor immunotherapeutic drugs have emerged, challenges faced in delivery these drugs, such as poor permeability low cell uptake rate, had prevented their widespread application. Recently, nanomaterials emerged a means for treatment different diseases due targeting properties, biocompatibility functionalities. Moreover, possess characteristics that overcome defects traditional immunotherapy, large drug loading capacity, precise easy modification, thus leading wide application immunotherapy. There are two main classes novel nanoparticles mentioned this review: organic (polymeric nanomaterials, liposomes lipid nanoparticles) inorganic (non-metallic metallic nanomaterials). Besides, fabrication method nanoparticles, Nanoemulsions, was also introduced. In summary, review article mainly discussed research progress based on past few years offers theoretical basis exploring strategies future.

Language: Английский

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Insight on nano drug delivery systems with targeted therapy in treatment of oral cancer

Nanomedicine Nanotechnology Biology and Medicine, Journal Year: 2023, Volume and Issue: 49, P. 102662 - 102662

Published: Feb. 4, 2023

Language: Английский

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Design, development, and drug delivery applications of graphene polymeric nanocomposites and bionanocomposites

Emergent Materials, Journal Year: 2023, Volume and Issue: 6(3), P. 777 - 807

Published: Feb. 6, 2023

Language: Английский

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Zero-dimensional nano-carbons: Synthesis, properties, and applications

Applied Physics Reviews, Journal Year: 2024, Volume and Issue: 11(2)

Published: April 19, 2024

Zero-dimensional (0D) nano-carbons, including graphene quantum dots, nanodiamonds, and carbon represent the new generation of carbon-based nanomaterials with exceptional properties arising from diverse phenomena, such as surface, size, edge effects, which strongly depend on carbon–carbon bond configuration (sp2, sp3, a mixture sp2 sp3) particle size. Their unique physicochemical properties, optical, electronic, magnetic, reactivity, catalytic are valuable for energy conversion storage, sensing, catalysis, optoelectronic devices, modern nanotechnologies, biomedical, many other applications. This review aims to provide insights into distinctive effects 0D nano-carbon microstructures their that crucial cutting-edge fundamental studies broad range multifunctional The key synthesis methods different types nano-carbons current advances characterization computational techniques study structures structure–property relationships also discussed. concludes status, challenges, future opportunities in this rapidly developing research field.

Language: Английский

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Nanomaterials-based advanced systems for photothermal / photodynamic therapy of oral cancer

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 272, P. 116508 - 116508

Published: May 15, 2024

Language: Английский

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Applications and Enhancement Strategies of ROS-based Non-invasive Therapies in Cancer Treatment

Redox Biology, Journal Year: 2025, Volume and Issue: unknown, P. 103515 - 103515

Published: Jan. 1, 2025

Language: Английский

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Functional nanomaterials and their potentials in antibacterial treatment of dental caries

Colloids and Surfaces B Biointerfaces, Journal Year: 2022, Volume and Issue: 218, P. 112761 - 112761

Published: Aug. 6, 2022

Language: Английский

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Nanomaterials: Breaking through the bottleneck of tumor immunotherapy

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 230, P. 123159 - 123159

Published: Jan. 5, 2023

Language: Английский

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Photothermal and natural activity-based synergistic antibacterial effects of Ti3C2Tx MXene-loaded chitosan hydrogel against methicillin-resistant Staphylococcus aureus

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 240, P. 124482 - 124482

Published: April 18, 2023

Language: Английский

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Reactive oxygen species creation by laser-irradiated indocyanine green as photodynamic therapy modality: an in vitro study

Lasers in Medical Science, Journal Year: 2023, Volume and Issue: 38(1)

Published: Sept. 14, 2023

Abstract Applications of lasers in phototherapy have been the trend for last few decades. The photodynamic therapy process normally depends on photosensitizers and laser beams. Through this study, indocyanine green has used as a photosensitizer, which is activated using lines between 750 805 nm. activity to do fluorescence by other pulsed sources tested technique, it proven that at 810, 940, 980nm are able excite with different extents. activation several (810, 980 nm) commonly surgical lasers. generated oxygen measured after irradiating lines. A comparison made irradiation pinpoint broad beam. It found wide beam more effective activating production. In end, concluded 810 940nm were dye, while did not show enough efficiency.

Language: Английский

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