Progress of Electrospun Nanofibrous Carriers for Modifications to Drug Release Profiles

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 289 - 289

Published: Dec. 9, 2022

Electrospinning is an advanced technology for the preparation of drug-carrying nanofibers that has demonstrated great advantages in biomedical field. Electrospun nanofiber membranes are widely used field drug administration due to their such as large specific surface area and similarity extracellular matrix. Different electrospinning technologies can be prepare different structures, those with a monolithic structure, core–shell Janus or porous structure. It also possible controlled-release functions, sustained release, delayed biphasic targeted release. This paper elaborates on drug-loaded using various concludes mechanisms behind controlled release drugs.

Language: Английский

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Electrospun Medical Sutures for Wound Healing: A Review

Polymers, Journal Year: 2022, Volume and Issue: 14(9), P. 1637 - 1637

Published: April 19, 2022

With the increasing demand for wound healing around world, level of medical equipment is also increasing, but sutures are still preferred personnel to solve closures. Compared with traditional sutures, nanofiber produced by combining preparation technology drug-eluting have greatly improved both mechanical properties and biological properties. Electrospinning has attracted more attention as one most convenient simple methods preparing functional nanofibers related sutures. This review firstly discusses structural classification performance analysis affecting manufacture use followed discussion electrospinning technology, then summarizes relevant research on absorbable non-absorbable Finally, several common polymers biologically active substances used in creating concluded, applications discussed, future prospects suggested.

Language: Английский

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Recent Progress in Electrospun Polyacrylonitrile Nanofiber-Based Wound Dressing

Polymers, Journal Year: 2022, Volume and Issue: 14(16), P. 3266 - 3266

Published: Aug. 11, 2022

Bleeding control plays a very important role in worldwide healthcare, which also promotes research and development of wound dressings. The healing process involves four stages hemostasis, inflammation, proliferation remodeling, is complex process, dressings play huge it. Electrospinning technology simple to operate. Electrospun nanofibers have high specific surface area, porosity, oxygen permeability, excellent mechanical properties, show great utilization value the manufacture As one most popular reactive functional synthetic polymers, polyacrylonitrile (PAN) frequently explored create for wide variety applications. In recent years, researchers invested application PAN Research on spun reviewed, future directions prospects electrospun are proposed.

Language: Английский

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Electrospun nanofiber-based glucose sensors for glucose detection

Frontiers in Chemistry, Journal Year: 2022, Volume and Issue: 10

Published: Aug. 11, 2022

Diabetes is a chronic, systemic metabolic disease that leads to multiple complications, even death. Meanwhile, the number of people with diabetes worldwide increasing year by year. Sensors play an important role in development biomedical devices. The efficient, stable, and inexpensive glucose sensors for continuous monitoring blood levels has received widespread attention because they can provide reliable data prevention diagnosis. Electrospun nanofibers are new kinds functional nanocomposites show incredible capabilities high-level biosensing. This article reviews based on electrospun nanofibers. principles sensor, types measurement, detection methods briefly discussed. principle electrospinning its applications advantages then introduced. provides comprehensive summary polymers nanomaterials nanofiber-based sensors. relevant comparisons enzymatic non-enzymatic discussed detail. main disadvantages evaluated, some solutions proposed. Finally, potential commercial improved

Language: Английский

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Recent Progress of the Preparation and Application of Electrospun Porous Nanofibers

Polymers, Journal Year: 2023, Volume and Issue: 15(4), P. 921 - 921

Published: Feb. 12, 2023

Electrospun porous nanofibers have gained a lot of interest recently in various fields because their adjustable structure, high specific surface area, and large number active sites, which can further enhance the performance materials. This paper provides an overview common polymers, preparation, applications electrospun nanofibers. Firstly, polymers commonly used to construct structures main pore-forming methods by electrospinning, namely template method phase separation method, are introduced. Secondly, recent air purification, water treatment, energy storage, biomedicine, food packaging, sensor, sound wave absorption, flame retardant, heat insulation reviewed. Finally, challenges possible research directions for future study discussed.

Language: Английский

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Insight into the superior piezophotocatalytic performance of BaTiO3//ZnO Janus nanofibrous heterostructures in the treatment of multi-pollutants from water

Applied Catalysis B Environment and Energy, Journal Year: 2023, Volume and Issue: 330, P. 122623 - 122623

Published: March 13, 2023

Language: Английский

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Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2022, Volume and Issue: 15(1)

Published: July 11, 2022

Abstract The skin is a complex layer system and the most important barrier between environment organism. In this review, we describe some widespread problems, with focus on eczema, which are affecting more people all over world. Most of treatment methods for atopic dermatitis (AD) focused increasing moisture protecting from bacterial infection external irritation. Topical transdermal treatments have specific requirements drug delivery. Breathability, flexibility, good mechanical properties, biocompatibility, efficacy patches used skin. Up to today, electrospun fibers mostly wound dressing. Their however, meet AD. Active agents can be incorporated into by blending, coaxial or side‐by‐side electrospinning, also physical absorption post‐processing. Drug release membranes affected polymer properties technique combine them patch. We in detail vitro mechanisms, parameters transport, their kinetics, including theoretical approaches. addition, present current research patch design. This review summarizes extensive know‐how as delivery systems, while underlining advantages prospective use dermatitis. article categorized under: Implantable Materials Surgical Technologies > Nanomaterials Implants Nanotechnology Tissue Repair Replacement Therapeutic Approaches Discovery Emerging

Language: Английский

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Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers

Biomolecules, Journal Year: 2022, Volume and Issue: 12(9), P. 1254 - 1254

Published: Sept. 7, 2022

Oral ulcers affect oral and systemic health have high prevalence in the population. There are significant individual differences etiology extent of disease among patients. In treatment ulcers, nanofiber films can control drug-release rate enable long-term local administration. Compared to other drug-delivery methods, avoid disadvantages frequent administration certain side effects. Electrospinning is a simple effective method for preparing films. Currently, electrospinning technology has made breakthroughs energy-saving large-scale production. This paper summarizes polymers that mucosal adhesion active pharmaceutical ingredients used ulcers. Moreover, therapeutic effects currently available electrospun on animal experiments clinical trials investigated. addition, solvent casting cross-linking methods be conjunction with techniques. Based literature, more systems different loading components inspired. These expected synergistic achieve better not only provides new possibilities drug-loaded nanofibers but also brings hope

Language: Английский

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Electrospun Nanofibers for Periodontal Treatment: A Recent Progress

International Journal of Nanomedicine, Journal Year: 2022, Volume and Issue: Volume 17, P. 4137 - 4162

Published: Sept. 1, 2022

Abstract: Periodontitis is a major threat to oral health, prompting scientists continuously study new treatment techniques. The nanofibrous membrane prepared via electrospinning has large specific surface area and high porosity. On the one hand, electrospun nanofibers can improve absorption capacity of proteins promote expression genes. other they cell adhesion properties prevent fibroblasts from passing through barrier membrane. Therefore, unique advantages in periodontal treatment. At present, many membranes with antibacterial, anti-inflammatory, tissue regeneration have been for First, this paper introduces process. Then, commonly used polymers treating periodontitis are summarized. Finally, different types presented, future evolution treat described. Graphical Keywords: periodontitis, electrospinning, membrane,

Language: Английский

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Multi-material electrospinning: from methods to biomedical applications

Materials Today Bio, Journal Year: 2023, Volume and Issue: 21, P. 100710 - 100710

Published: June 25, 2023

Electrospinning as a versatile, simple, and cost-effective method to engineer variety of micro or nanofibrous materials, has contributed significant developments in the biomedical field. However, traditional electrospinning single material only can produce homogeneous fibrous assemblies with limited functional properties, which oftentimes fails meet ever-increasing requirements applications. Thus, multi-material referring engineering two more kinds been recently developed enable fabrication diversified complex structures advanced performance for greatly promoting development. This review firstly gives an overview modalities, highlight on their features accessibility constructing different structures. A perspective how opens up new opportunities specific applications, i.e., tissue drug delivery, is also offered.

Language: Английский

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