Nanoscale,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Achieving
accurate
and
efficient
tumor
imaging
is
crucial
in
the
field
of
treatment,
as
it
facilitates
early
detection
precise
localization
tissues,
thereby
informing
therapeutic
strategies
surgical
interventions.
The
optical
technology
within
second
near-infrared
(NIR-II)
window
has
garnered
significant
interest
for
its
remarkable
benefits,
such
enhanced
tissue
penetration
depth,
superior
signal-to-background
ratio
(SBR),
minimal
autofluorescence,
reduced
photon
attenuation,
lower
scattering.
This
review
explained
design
optimization
nano-agents
responsive
to
NIR-II
window,
single-walled
carbon
nanotubes,
quantum
dots,
lanthanum-based
nanomaterials,
noble
metal
nanomaterials.
These
enable
non-invasive,
deep-tissue
with
high
spatial
resolution
their
properties
significantly
improve
accuracy,
efficiency,
versatility
imaging-guided
treatments.
And
we
discussed
characteristics
advantages
fluorescence
(FL)/photoacoustic
(PA)
providing
a
comprehensive
overview
latest
research
progress
different
FL/PA
therapy.
Furthermore,
exhaustively
reviewed
applications
multifunctional
nano-phototherapy
technologies
carried
out
by
light
including
photothermal
therapy
(PTT),
photodynamic
(PDT),
combined
modalities
like
photothermal-chemodynamic
(PTT-CDT),
photothermal-chemotherapy
(PTT-CT),
photothermal-
immunotherapy
(PTT-IO).
integrated
approaches
have
gradually
matured
over
past
decade
are
expected
become
safe
effective
non-invasive
treatment.
Finally,
outlined
prospects
challenges
development
innovation
diagnosis
nanoplatform.
aims
provide
insightful
perspectives
future
advancements
treatment
platforms.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 12, 2024
Abstract
The
lanthanide
complex,
characterized
by
narrow
emission
bands,
large
Stokes
shifts,
long
luminescence
lifetime,
robust
resistance
to
photobleaching,
and
magnetic
properties,
affords
significant
promise
for
molecular
imaging
biosensing
applications.
While
most
complexes
emitting
visible
light
are
extensively
studied
cellular‐level
detection
bioimaging,
near‐infrared‐emitted
(700–1700
nm)
compounds
exhibit
more
favorable
properties
bioimaging
biosensing,
ascribed
from
deeper
penetration
reduced
bleaching
effects.
Besides,
the
complex
with
higher
resonance
signals
can
enhance
image
resolution
sensitivity,
offering
precise
analysis.
However,
widespread
use
of
high‐efficiency
is
currently
impeded
lack
design
approaches
improving
sensitization
chromophores
extended
excitation
wavelengths.
In
this
review,
some
fundamental
theories
strategies
summarized
imaging,
lifetime‐engineered
dual‐modal
now
highlight
a
selection
review
addresses
existing
gap
in
literature
proposing
feasible
fluorescent
properties.
Concurrently,
future
challenges
opportunities
field
probes
discussed.
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 9, 2024
The
field
of
oncology
has
transformed
in
recent
years,
with
treatments
shifting
from
traditional
surgical
resection
and
radiation
therapy
to
more
diverse
customized
approaches,
one
which
is
immunotherapy.
ICD
(immunogenic
cell
death)
belongs
a
class
regulatory
death
modalities
that
reactivate
the
immune
response
by
facilitating
interaction
between
apoptotic
cells
releasing
specific
signaling
molecules,
DAMPs
(damage-associated
molecular
patterns).
inducers
can
elevate
expression
proteins
optimize
TME
(tumor
microenvironment).
use
nanotechnology
shown
its
unique
potential.
Nanomaterials,
due
their
tunability,
targeting,
biocompatibility,
have
become
powerful
tools
for
drug
delivery,
immunomodulators,
etc.,
significant
efficacy
clinical
trials.
In
particular,
these
nanomaterials
effectively
activate
ICD,
trigger
potent
anti-tumor
response,
maintain
long-term
tumor
suppression.
Different
types
nanomaterials,
such
as
biological
membrane-modified
nanoparticles,
self-assembled
nanostructures,
metallic
mesoporous
materials,
hydrogels,
play
respective
roles
induction
structures
mechanisms
action.
Therefore,
this
review
will
explore
latest
advances
application
common
discuss
how
they
provide
new
strategies
cancer
therapy.
By
gaining
deeper
understanding
mechanism
action
researchers
develop
precise
effective
therapeutic
approaches
improve
prognosis
quality
life
patients.
Moreover,
hold
promise
overcome
resistance
conventional
therapies,
minimize
side
effects,
lead
personalized
treatment
regimens,
ultimately
benefiting
treatment.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101488 - 101488
Published: Jan. 13, 2025
Photothermal
therapy
(PTT)
utilizes
photothermal
materials
to
convert
light
energy
into
heat
under
external
irradiation,
effectively
killing
cancer
cells.
Therefore,
the
efficacy
of
PTT
is
largely
determined
by
conversion
efficiency
material.
In
this
study,
we
developed
a
novel
ladder-type
conjugated
polymer,
PPAPA,
via
phenazine
ring
fusion
reaction.
PPAPA
exhibits
high
75.2
%
1064
nm
laser
comparable
benchmark
organic
agent
SWCNT.
Notably,
synthesis
avoids
use
noble
metal
catalysts,
eliminating
potential
biotoxicity
caused
residual
catalysts
and
ensuring
optimal
stability
efficiency.
Furthermore,
demonstrates
efficient
near-infrared
II
(NIR-II)
enabling
deeper
tissue
penetration
reduced
absorption.
This
work
comprehensively
investigates
properties
evaluates
its
in
tumor
PTT,
demonstrating
as
effective
therapeutic
strategy
for
treatment,
offering
new
hope
patients.
Aggregate,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 24, 2025
ABSTRACT
The
field
of
molecular
charge
transfer
cocrystals
(CTCs)
has
advanced
rapidly
in
recent
years,
with
much
work
focused
on
their
use
optoelectronic
devices,
photoacoustic
imaging,
photothermal
therapy
(PTT),
optical
waveguides,
seawater
desalination,
and
more.
Organic
CTCs
are
particular
interest
because
unique
phototherapeutic
effects
phototherapy
remarkable
imaging
capabilities
fluorescence,
magnetic
resonance,
further
enhancing
significance
medical
applications.
However,
the
biomedicine
been
limited,
few
reported
biological
Hence,
there
is
a
growing
CT‐derived
functional
potential
contenders
for
targeted
controlled
biomedical
applications
such
as
bacteria
inhibition,
cancer
eradication,
tissue
regeneration.
This
review
offers
insight
into
advancements
crafting
producing
CT‐based
materials
attributes.
In
addition,
it
outlines
current
obstacles
future
prospects
this
burgeoning
research
domain,
aiming
to
propel
continued
advancement
biomaterials
toward
enhanced
utilities.
Overall,
cocrystal‐based
near‐infrared
(NIR)
have
revolutionize
wide
range
technological
an
active
area
chemistry,
science,
nanotechnology.
