International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138693 - 138693
Published: Dec. 1, 2024
Language: Английский
Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 11
Published: Jan. 24, 2025
The liver is a vital organ responsible for numerous metabolic processes in the human body, including metabolism of drugs and nutrients. After damage, can rapidly return to its original size if causative factor promptly eliminated. However, when harmful stimulus persists, liver’s regenerative capacity becomes compromised. Substantial theoretical feasibility has been demonstrated at levels gene expression, molecular interactions, intercellular dynamics, complemented by successful animal studies. robust model carrier that closely resemble physiology are still lacking translating these theories into practice. potential regeneration central focus ongoing research. Over past decade, advent organoid technology provided improved models materials advancing research efforts. Liver represents novel vitro culture system. several years refinement, organoids now accurately replicate morphological structure, nutrient drug metabolism, secretory functions, providing disease Regenerative medicine aims or tissue functions repair replace damaged tissues, restore their structure function, stimulate tissues organs within body. possess same function as tissue, offering serve viable replacement liver, aligning with goals medicine. This review examines role
Language: Английский
Citations
1
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: July 27, 2024
Abstract Regenerative biomedicine has emerged as a forefront area in medical research, heralding new era of therapeutic strategies. This review delineates the integration 2D materials (2DMs) within biomedical engineering, leveraging their superior physicochemical attributes for enhance outcomes. The synergistic interaction between biomacromolecules and 2DMs is explored, demonstrating potential to mitigate limitations inherent each while simultaneously augmenting beneficial properties. In particular, incorporating into hydrogels highlights capability mechanical strength hydrogels, providing biomimetic scaffold tissue engineering regeneration cancer diagnosis therapy. An overview synthetic methodologies are provided 2DMs, elucidating dynamics with biomacromolecules. primarily concentrates on applications biomacromolecule‐reinforced 2DM across various fields, including bone wound healing, neural cardiac well delivery drugs genes, therapy, biosensing technologies. Finally, discusses existing challenges future outlook developing using underlining transformative regenerative medicine.
Language: Английский
Citations
5
Gels, Journal Year: 2024, Volume and Issue: 10(10), P. 653 - 653
Published: Oct. 12, 2024
Biomedical engineering, especially tissue is trying to provide an alternative solution generate functional organs/tissues for use in various applications. These include beyond the final goal of transplantation, disease modeling and drug discovery as well. The aim this study comprehensively review existing literature on hydrogel-based vascularized organ (i.e., liver, pancreas, kidneys, intestine, stomach spleen) engineering abdominal organs.
Language: Английский
Citations
4
Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
This review provides a comprehensive overview of vascularized cell spheroids, highlighting recent advancements in biofabrication, key strategies for engineering vascular networks, and their applications tissue models regenerative medicine.
Language: Английский
Citations
0
Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112401 - 112401
Published: March 1, 2025
Language: Английский
Citations
0
Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00365 - e00365
Published: Oct. 1, 2024
Language: Английский
Citations
2
Polymer Engineering and Science, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 2, 2024
Abstract Additive manufacturing (AM) is widely recognized for its flexibility, structural complexity, customizability, and sustainability. Within the realm of AM technology, direct ink writing (DIW) stand out due to material diversity, high resolution, capacity free‐form design. It enjoys widespread applications in biomedicine engineering, making it a key advanced method crafting design‐free, multifunctional, stable items. Herein, review DIW polymer‐based materials presented. starts with an overview various fillers polymer composites, followed by in‐depth discussion diverse methods customizing across different classes. Subsequently, delves into emerging materials, encompassing their utility biology, electrical energy storage, electronics, robotics. Finally, addresses current challenges prospects associated DIW, aiming elucidate potential pathways future innovations. Highlights one most popular techniques 3D printing. Describes application recent years. Outlines advances hydrogels, 4D myriad materials. Discusses outlooks provide guidance future.
Language: Английский
Citations
2
Bioactive Materials, Journal Year: 2024, Volume and Issue: 43, P. 162 - 180
Published: Sept. 23, 2024
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138693 - 138693
Published: Dec. 1, 2024
Language: Английский
Citations
0