Current Research in Pharmacology and Drug Discovery,
Journal Year:
2021,
Volume and Issue:
2, P. 100034 - 100034
Published: Jan. 1, 2021
Prostate
cancer
(PCa)
is
a
major
cause
of
morbidity
and
mortality
in
men
worldwide.
A
geographic
variation
on
the
burden
disease
suggested
that
environment,
genetic
makeup,
lifestyle,
food
habits
modulate
one's
susceptibility
to
disease.
Although
it
has
been
generally
thought
be
an
older
age
disease,
awareness
timely
execution
screening
programs
have
managed
contain
population
over
last
decades,
incidence
still
increasing
younger
than
50.
Existing
treatment
efficient
for
PCa
localized
responsive
androgen.
However,
androgen
resistant
metastatic
are
challenging
treat.
Conventional
radiation
chemotherapies
associated
with
severe
side
effects
addition
being
exorbitantly
expensive.
Many
isolated
phytochemicals
extracts
plants
used
traditional
medicine
known
their
safety
diverse
healing
properties,
including
many
varying
levels
anti-PCa
activities.
discussed
here,
as
shown
by
laboratories,
inhibit
tumor
cell
growth
proliferation
interfering
components
pathways
responsible
enhanced
proliferation,
metabolism,
angiogenesis,
invasion,
metastasis
prostate
cells
while
upregulating
mechanisms
death
cycle
arrest.
Notably,
these
agents
simultaneously
target
multiple
cellular
pathways.
We
analyzed
available
literature
provided
update
this
issue
review
article.
Food Chemistry,
Journal Year:
2022,
Volume and Issue:
384, P. 132467 - 132467
Published: Feb. 16, 2022
This
review
offers
a
vision
of
the
chemical
behaviour
natural
ingredients,
synthetic
drugs
and
other
related
compounds
complexed
using
cyclodextrins.
The
takes
care
different
sections
to
i)
inclusion
complexes
formation
with
cyclodextrins,
ii)
determination
constant,
iii)
most
used
methods
prepare
host
in
non-polar
cavity
cyclodextrins
iv)
analytical
techniques
evidence
inclusion.
provides
literature
that
shows
application
improve
physical,
chemical,
biological
characteristics
food
including
solubility,
stability
their
elimination/masking.
Moreover,
also
examples
commercial
food/supplement
products
indicate
can
be
generate
biotechnological
substances
innovative
properties
development
products.
Biology,
Journal Year:
2022,
Volume and Issue:
11(2), P. 239 - 239
Published: Feb. 4, 2022
This
review
outlines
the
health
benefits
associated
with
regular
consumption
of
tomatoes
and
tomato
products.
The
first
section
provides
a
detailed
account
horticultural
techniques
that
can
impact
quality
fruit
its
nutritional
properties,
including
water
availability,
light
intensity,
temperature,
growing
media.
next
information
on
components
are
likely
to
contribute
effects.
then
details
some
consumption,
anticancer
cardiovascular
neurodegenerative
diseases
skin
health.
also
discusses
have
gut
microbiome
benefits,
reducing
risk
inflammatory
bowel
diseases.
Other
eating
discussed
in
relation
effects
diabetes,
immune
response,
exercise
recovery,
fertility.
Finally,
this
addresses
negative
occur
as
result
overconsumption
products
lycopene
supplements.
Foods,
Journal Year:
2021,
Volume and Issue:
10(11), P. 2634 - 2634
Published: Oct. 30, 2021
Cordyceps
spp.
mushrooms
have
a
long
tradition
of
use
as
natural
raw
material
in
Asian
ethnomedicine
because
their
adaptogenic,
tonic
effects
and
ability
to
reduce
fatigue
stimulate
the
immune
system
humans.
This
review
aims
present
chemical
composition
medicinal
properties
Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(2), P. 232 - 232
Published: Jan. 26, 2022
Lycopene
is
a
bioactive
red
pigment
found
in
plants,
especially
fruits
and
vegetables,
including
tomato,
pink
guava,
papaya,
grapefruit,
watermelon.
Several
research
reports
have
advocated
its
positive
impact
on
human
health
physiology.
For
humans,
lycopene
an
essential
substance
obtained
from
dietary
sources
to
fulfil
the
body
requirements.
The
production
of
reactive
oxygen
species
(ROS)
causing
oxidative
stress
downstream
complications
include
one
major
concerns
worldwide.
In
recent
years,
counter
strategies
attracted
biomedical
order
manage
emerging
issues.
has
been
reported
directly
interact
with
ROS,
which
can
help
prevent
chronic
diseases,
diabetes
neurodegenerative
cardiovascular
diseases.
this
context,
present
review
article
was
written
provide
accumulative
account
protective
ameliorative
effects
coronary
artery
disease
(CAD)
hypertension,
are
leading
causes
death
potent
antioxidant
that
fights
ROS
and,
subsequently,
complications.
It
reduces
blood
pressure
via
inhibiting
angiotensin-converting
enzyme
regulating
nitrous
oxide
bioavailability.
plays
important
role
lowering
LDL
(low-density
lipoproteins)
improving
HDL
(high-density
levels
minimize
atherosclerosis,
protects
onset
hypertension.
Various
studies
exhibited
combating
competence
treatment
these
Owing
all
antioxidant,
anti-diabetic,
anti-hypertensive
properties,
provides
potential
nutraceutical
curing
ability
against
Biomedicine & Pharmacotherapy,
Journal Year:
2023,
Volume and Issue:
161, P. 114428 - 114428
Published: Feb. 24, 2023
The
potent
relation
between
lycopene
intake
and
reduced
incidence
of
a
variety
cancers
has
an
increasing
interest.
This
comprehensive
review
aims
to
highlight
the
in
vivo
vitro
research
evaluating
anticancer
mechanisms
by
underlining
experiment
conditions.
In
addition
these,
general
characterization
been
explained.
A
collection
relevant
scientific
pharmacological
articles
from
following
databases
PubMed/MedLine,
Web
Science,
Scopus,
TRIP
database,
Google
Scholar
on
molecular
action
cellular
effects
various
types
tumors
was
performed.
potential
described
cells,
animal
studies,
some
clinical
trials.
It
revealed
that
is
mainly
due
its
powerful
singlet-oxygen
quencher
characteristics,
simulation
detoxifying/antioxidant
enzymes
production,
initiation
apoptosis,
inhibition
cell
proliferation
cycle
progression
as
well
modulations
gap
junctional
communication,
growth
factors,
signal
transduction
pathways.
highlighted
properties
are
primarily
linked
factors
including;
dose,
presence
drug
delivery
systems,
type
cancer,
tumor
size,
treatment
time.
Journal of Inorganic and Organometallic Polymers and Materials,
Journal Year:
2023,
Volume and Issue:
33(12), P. 3750 - 3759
Published: June 14, 2023
Abstract
This
work
aimed
at
the
green
synthesis
of
multifunctional
zinc
oxide
nanoparticles
(ZnO
NPs)
using
Solanum
Lycopersicum
(SL)
fruit
juice
to
act
as
antibacterial/cancer/UV
sunscreens.
The
obtained
ZnO
NPs
were
examined
for
optical
properties,
cytotoxicity
human
lung
fibroblast
(WI-38)
and
hepatocellular
carcinoma
(HePG2)
cell
lines,
antibacterial
activity
against
Gram-negative
Escherichia
coli
Gram-positive
Staphylococcus
aureus
.
antioxidant
in
vitro
sun
protection
factor
(SPF)
synthesized
carried
out
by
spectrophotometric
methods.
formation
pure
phase
structure
characteristic
functional
group
confirmed
XRD,
FTIR,
UV–Vis
diffuse
reflectance
analysis.
SEM
image
showed
that
have
a
quasi-spherical
shape
with
size
about
39
±
12
nm.
high
potency
sunscreens
(in
SPF
=
16.8)
mild
agents.
Notably,
enhanced
cytotoxic
cells
their
pathogenic
bacteria.
SL
can
play
triple
role
acting
solvent,
reducing
agent
stabilizer
which
facilitates
sunscreen
has
anti-carcinogenic
properties.
Food Chemistry X,
Journal Year:
2024,
Volume and Issue:
24, P. 101953 - 101953
Published: Nov. 2, 2024
Nanotechnology
plays
a
pivotal
role
in
food
science,
particularly
the
nanoencapsulation
of
bioactive
compounds,
to
enhance
their
stability,
bioavailability,
and
therapeutic
potential.
This
review
aims
provide
comprehensive
analysis
encapsulation
emphasizing
characteristics,
applications,
implications
for
human
health.
work
offers
detailed
comparison
polymers
such
as
sodium
alginate,
gum
Arabic,
chitosan,
cellulose,
pectin,
shellac,
xanthan
gum,
while
also
examining
both
conventional
emerging
techniques,
including
freeze-drying,
spray-drying,
extrusion,
coacervation,
supercritical
anti-solvent
drying.
The
contribution
this
lies
highlighting
improving
system
controlling
release
rates,
maintaining
bioactivity
under
extreme
conditions,
reducing
lipid
oxidation.
Furthermore,
it
explores
recent
technological
advances
aimed
at
optimizing
processes
targeted
therapies
functional
foods.
findings
underline
significant
potential
not
only
supplements
foods
but
supportive
medical
treatments,
showcasing
its
relevance
health
various
contexts.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e25261 - e25261
Published: Jan. 29, 2024
Due
to
its
nutritional
and
bioactive
content,
tomato
pomace
(TP)
remains
among
the
world's
richest
fruits
vegetables.
Tomatoes
TP
(generated
coproduct)
are
a
very
rich
source
of
lycopene
other
carotenoid
compounds
contain
an
essential
amount
polyphenols,
policosanol,
phytosterols,
organic
acids,
dietary
fibers,
minerals,
vitamins.
is
promising
significant
with
antioxidant
antimicrobial
potential.
Therefore,
their
consumption
known
be
effective
in
preventing
certain
chronic
diseases.
For
example,
prevents
prostate
cancer
acts
as
hepatoprotector
genoprotector
against
mycotoxins,
pesticide
residues,
heavy
metals.
Thus,
valorization
food
ingredient
can
great
health,
economic
environmental
interest
contribute
improving
nutrition
security.
During
last
decades,
considerable
efforts
have
been
made
valorize
crucial
functional
improving:
(i)
properties,
(ii)
sensory
characteristics
(iii)
shelf
life
many
foods.
The
current
review
aims
update
summarize
knowledge
on
recent
applications
TP,
particularly
use
improve
properties
Food Chemistry Advances,
Journal Year:
2024,
Volume and Issue:
4, P. 100656 - 100656
Published: Feb. 28, 2024
In
this
work,
a
completely
green
method
was
applied
for
the
extraction
of
lycopene
from
tomato
skins
waste.
The
combination
ultrasound-assisted
technique
(UAE)
and
use
volatile
natural
deep
eutectic
solvent
(VNADES)
menthol:
thymol
1:1
allowed
to
obtain
process.
Lycopene
content
assessed
by
HPLC-DAD
compared
with
yields
obtained
using
α-pinene
n-hexane
as
solvents.
evaporation
DES
menthol:thymol
conducted
Vacuum
Vortex
Evaporator.
highest
concentration
extracted
(735.9
mg/g
dried
extract
(DE))
terpene-based
solvents;
468.1
358.7-484.2
DE
were
recovered
menthol/thymol
azeotropic
mixture
such,
respectively.
Nutrients,
Journal Year:
2021,
Volume and Issue:
13(2), P. 496 - 496
Published: Feb. 3, 2021
Due
to
the
constantly
increasing
number
of
cases,
prostate
cancer
has
become
one
most
important
health
problems
modern
societies.
This
review
presents
current
knowledge
regarding
role
nutrients
and
foodstuff
consumption
in
etiology
development
malignancies,
including
potential
mechanisms
action.
The
results
several
vivo
vitro
laboratory
experiments
as
well
those
reported
by
clinical
epidemiological
research
studies
carried
out
around
world
were
analyzed.
outcomes
these
clearly
show
influence
both
food
products
on
prevention
cancer.
Consumption
certain
(saturated
trans
fatty
acids)
(e.g.,
processed
meat
products)
leads
disruption
hormonal
regulation,
induction
oxidative
stress
inflammation,
alteration
growth
factor
signaling
lipid
metabolism,
which
all
contribute
carcinogenesis.
On
other
hand,
a
high
vegetables,
fruits,
fish,
whole
grain
exerts
protective
and/or
therapeutic
effects.
Special
bioactive
functions
are
assigned
compounds
such
flavonoids,
stilbenes,
lycopene.
Since
dietary
pattern
is
modifiable
risk
cancer,
awareness
beneficial
harmful
effects
individual
ingredients
great
importance
global
strategy
against
