Frontiers in Bioscience-Scholar,
Journal Year:
2022,
Volume and Issue:
14(2), P. 12 - 12
Published: May 6, 2022
The
COVID-19
pandemic
has
provided
an
opportunity
for
repurposing
of
drugs,
including
complex,
natural
to
meet
the
global
need
safe
and
effective
antiviral
medicines
which
do
not
promote
multidrug
resistance
nor
inflate
medical
costs.
author
herein
describes
his
own
herbal
tinctures,
previously
prepared
oncology,
into
a
possibly
synergistic,
anti-COVID
41
"herb"
formula
extracts
derived
from
36
different
plants
medicinal
mushrooms.
A
method
multi-sample
in
vitro
testing
green
monkey
kidney
vero
cells
is
proposed
Hypothesis
that
even
such
large
combination,
potency
may
be
preserved,
along
with
therapeutic
synergy,
smoothness,
complexity.
possibility
formula's
improve
age
considered,
suitable
it.
Collaborative
research
inquiries
are
welcome.
Current Medicinal Chemistry,
Journal Year:
2022,
Volume and Issue:
30(31), P. 3506 - 3526
Published: Oct. 6, 2022
Abstract:
Cinnamaldehyde
(CNM)
is
a
cyclic
terpene
alcohol
found
as
the
major
compound
of
essential
oils
from
some
plants
genus
Cinnamomum
(Lauraceae).
CNM
has
several
reported
pharmacological
activities,
including
antimicrobial,
antivirulence,
antioxidant,
and
immunomodulatory
effects.
These
properties
make
an
attractive
lead
molecule
for
development
anti-infective
agents.
In
this
descriptive
review,
we
discuss
application
in
experimental
models
microbial
infection
using
invertebrate
vertebrate
organisms.
(pure
or
formulations)
been
successfully
applied
treatment
infections
caused
by
range
bacterial
(such
Cronobacter
sakazakii,
Escherichia
coli,
Listeria
monocytogenes,
Mycobacterium
tuberculosis,
Pseudomonas
aeruginosa,
Salmonella
enterica,
Staphylococcus
aureus,
Streptococcus
agalactiae,
Vibrio
cholerae)
fungal
Aspergillus
fumigatus,
Candida
albicans
Cryptococcus
neoformans)
pathogens.
All
these
evidence-based
findings
have
promoted
use
cinnamaldehyde
leading
developing
new
anti-
infective
drugs.
Biocell,
Journal Year:
2023,
Volume and Issue:
47(4), P. 677 - 695
Published: Jan. 1, 2023
Indian
medicinal
plants
are
referred
to
as
the
"nectar
of
life"
owing
their
phytochemicals
and
bioactive
complexes
that
beneficial
in
treating
diseases.
Coronavirus
disease
2019
(COVID-19)
is
a
global
health
issue
without
any
proper
medication.
The
indigenous
India
can
be
exploited
control
precise
signs
SARS-CoV-2.
Ministry
AYUSH
(Ayurveda,
Yoga
Naturopathy,
Unani,
Siddha,
Homeopathy)
has
advised
routine
usage
for
COVID-19.
Medicinal
like
Zingiber
officinalis,
Azadirachta
indica,
Ocimum
sanctum,
Nigella
sativa,
Withania
somnifera,
Curcuma
longa,
Piper
nigrum,
Allium
sativum,
Tinospora
cordifolia,
etc.
have
immunity-boosting,
antiviral,
antibacterial,
antioxidant
anti-inflammatory
actions
suppress
treat
symptoms
In
vitro,
vivo
well
silico
validation,
these
help
us
manage
COVID-19
disease.
This
integration
traditional
knowledge
prophylaxis
corona
infection
current
skills
validating
it
development
powerful
therapeutic
approaches
will
more
efficiently
resolve
different
clinical
aspects
review
focuses
on
both
emergent
methods
prevent
with
various
along
phytochemicals.
In
the
wake
of
Covid-19
crisis,
a
need
has
arisen
to
prevent
and
treat
two
related
conditions,
Covid
vaccine
injury
long
Covid,
both
which
have
significant
vascular
component.
Therefore,
management
these
conditions
require
development
strategies
or
dissolve
blood
clots
restore
circulatory
health.
This
review
summarizes
evidence
on
that
can
be
applied
injuries
based
similar
mechanisms
action.
Jurnal Penelitian Pendidikan IPA,
Journal Year:
2023,
Volume and Issue:
9(5), P. 1 - 7
Published: May 31, 2023
Cinnamon
is
a
spice
commodity
that
contains
chemical
compounds
and
bioactive
components
have
the
potential
to
be
developed
as
medicinal
raw
materials
in
pharmaceutical
industry.
Biological
activity
cinnamon
can
increase
stimulate
body's
immune
system.
This
study
aims
present
summary
of
literature
review
unify
overall
information
on
bioactivity
compound
content
cinnamon.
The
research
method
uses
with
Preferred
Reporting
Items
for
Systematic
Review
Meta-Analysis
(PRISMA)
meta-analysis
approach.
original
articles
shows
variety
properties
found
plants
because
alleged
including
cinnamaldehyde,
phenolics,
flavonoids,
alkaloids,
saponins,
tannins,
polyphenols,
triterpenoids
bioactivities,
namely
immunomodulator,
antifungal,
antioxidant,
anti-inflammatory,
antibacterial,
antidiabetic
A-Glucosidase
enzyme
activity.
From
some
results,
plant
parts
been
shown
many
pharmacological
it
productivity
drugs
using
natural
ingredients
Global Journal of Medical Pharmaceutical and Biomedical Update,
Journal Year:
2023,
Volume and Issue:
18, P. 24 - 24
Published: Oct. 10, 2023
Carbapenem
was
originally
regarded
as
a
cornerstone
therapeutic
for
Gram-negative
bacterial
infections
that
could
be
fatal,
but
these
pathogens
are
rapidly
acquiring
resistance
to
it
by
various
methods
such
forming
biofilms,
mutations
in
porin
channels,
overexpression
of
efflux
pumps,
altering
or
modifying
antibiotics,
and
horizontal
gene
transfer
biomarkers.
Among
pathogens,
the
World
Health
Organization
has
prioritized
Acinetobacter
baumannii
“pathogen
concern.”
A.
strains
have
variety
antibiotics
pathways,
making
them
resistant
majority
antibiotics.
Antibiotics
used
indiscriminately
excessively,
causing
extensive
natural
selection
pressure
allowing
just
most
versatile
variants
flourish.
Evolutionary
changes
unavoidable,
widespread
utilization
antimicrobials
communities,
hospitals,
agriculture
industries
is
certainly
contributing
outbreak.
Antibiotic
resulted
number
adverse
outcomes
inadequacy
antimicrobials,
persistent
infections,
physical
ailments
cause
patients
lose
momentum,
longer
stay
hospital,
increased
mortality,
morbidity,
well
cost
can
overburden
even
hospitals.
Therefore,
optimizing
efficient
alternate
antibacterial
compounds
critical
aspect
addressing
problem
antibiotic
resistance.
Various
studies
(
vitro
)
done
scientists
researchers
illustrated
efficacy
plant
extracts
their
essential
oils
against
other
pathogens.
The
urgent
need
do
research
vivo
more
screening
products
parts,
which
might
lead
discovery
novel
therapeutically
agents
infections.
Annals of Phytomedicine An International Journal,
Journal Year:
2022,
Volume and Issue:
COVID-19 Special(3)
Published: July 1, 2022
COVID-19
has
changed
the
way
of
living
and
altered
lifestyle
in
many
ways
since
2019
its
various
mutant
forms
were
responsible
for
millions
deaths
globally.According
to
reports,
this
virus
was
more
dangerous
people
with
weak
immune
systems,
who
already
had
certain
illnesses.Therefore,
World
Health
Orga
nization
a
nd
Ministry
Ayu
sh
recommend
easy-to-a
ccess
immu
nityboosting
foods,
regular
exercise
yoga
lead
healthy
fight
against
COVID
infection.As
most
plants
are
powerful
sources
several
phytocompounds
biological
activity
list
includes
variety
medicinal
or
therapeutic
plant
species
such
as
ashwagandha,
aloe
vera,
garlic,
neem,
giloy,
harar,
lemon
grass
more.The
parts
these
contain
beneficial
elements
su
ch
phenols,
flavonoids,
tannins
vita
mins
that
strengthen
system
improve
health.In
India,
there
different
climatic
zones
where
herbs
can
be
grown
abundantly
regions.These
do
not
directly
cure
infection
but
plays
significant
role
controlling
disease
conditions
which
similar
like
cold,
cough,
fever,
diabetes,
obesity,
heart
problems
especially
respiratory
problems.A
ability
mitigate
disease's
adverse
effects.Thus,
increasing
immunity
through
use
assist
us
future
reducing
severity
diseases,
including
infection.
Frontiers in Pharmacology,
Journal Year:
2022,
Volume and Issue:
13
Published: Oct. 26, 2022
The
herbo-mineral
formulation,
Divya-Swasari-Vati
(DSV),
is
a
well-known
Ayurvedic
medication
for
respiratory
ailments.
In
recent
pre-clinical
study,
DSV
rescued
humanized
zebrafish
from
SARS-CoV-2
S-protein-induced
pathologies.
This
merited
an
independent
evaluation
of
as
entry
inhibitor
in
the
human
host
cell
and
its
effectiveness
ameliorating
associated
cytokine
production.
ELISA-based
protein-protein
interaction
study
showed
that
inhibited
interactions
recombinant
ACE
2
with
three
different
variants
S
proteins,
namely,
mut
1
(the
first
reported
variant),
(W436R
variant)
3
(D614G
variant).
Entry
vesicular
stomatitis
(VSVppSARS-2S)
pseudovirus,
having
firefly
luciferase
EGFP
reporters,
was
assessed
through
assay
fluorescent
microscopy.
exhibited
dose-dependent
inhibition
VSVppSARS-2S
pseudovirus
into
lung
epithelial
A549
cells
also
suppressed
elevated
levels
secreted
pro-inflammatory
cytokines
such
interleukin-6
(IL-6),
interleukin-1β
(IL-1β)
tumor
necrosis
factor-α
(TNF-α)
induced
by
viral
infection
mimicking
Poly
I:C-,
S-protein-
pseudovirus.
immune
cells,
moderated
TNF-α-mediated
NF-κB
induction,
manner.
observed
anti-viral
effect
against
attributable
to
presence
metabolites
Summarily,
observations
this
biochemically
demonstrated
interfered
between
S-protein
receptor
which
consequently,
concomitant
induction
inflammatory
response.
Madras Agricultural Journal,
Journal Year:
2023,
Volume and Issue:
110(March)
Published: Jan. 1, 2023
Functional
foods
are
in
great
demand
worldwide
because
of
their
many
health
benefits.
As
milk
is
a
nutrient-dense
diet
that
comprises
all
vital
nutrients,
it
can
be
utilized
as
the
primary
base
to
produce
variety
functional
foods.
Ginger,
cinnamon
and
pumpkin
possess
tremendous
nutritional
therapeutic
properties
such
stimulating
digestive
system,
lowering
blood
cholesterol
levels
exhibiting
antioxidant,antidiabetic,
antibacterial,
antiviral
anti-carcinogenic
activities,
preventing
oxidative
stress-related
diseases
ageing
process.
In
this
study,
aqueous
ginger
extracts
pulp
were
made
like
antioxidant
activity
total
phenolic
content
have
been
evaluated.
beverage
was
using
milk,
extract,
extract
yellow
pulp.
The
level
inclusion
these
components
optimized
D-optimal
mixture
design
(Design
Expert
Software)
with
regard
sensory
attributes.The
chosen
based
on
desirability
range
assigned
each
response.
incorporation
pulp,
at
40%,
10%,
20%,
30%
respectively.
found
69.95
±
0.07
%,
56.45
0.08
25.80
0.10
60.53
0.03
%
450.88
mgGAE/100g,
106.93
0.02
15.59
0.09
mgGAE/100g
280.63
respectively
