Siling Decoction Ameliorates Adenine-Induced Renal Fibrosis in Rats by the AKT/IKKβ/NFκB Signaling Pathway DOI
Lianlin Zeng, Yu‐Chuan Lin, Haixu Chen

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156228 - 156228

Published: Nov. 8, 2024

Language: Английский

The Dual Role of LncRNAs in Hepatocellular Carcinoma: Friend and Foe DOI Creative Commons

Farzaneh Abam,

‪Saeid Ghorbian

Gastroenterology & Endoscopy, Journal Year: 2024, Volume and Issue: 2(4), P. 186 - 195

Published: June 4, 2024

In eukaryotes, RNA molecules called long non-coding RNAs (LncRNAs) have been found. Molecules that exceed 200 base pairs in length are incapable of coding for proteins. Studying the function LncRNAs cancer has main focus current investigation, which significantly impacted protein integrity and stability. can be regulated through various pathways, leading to chromatin changes methylation or as miRNA sponges. The most common type liver tumor worldwide is hepatocellular carcinoma (HCC), accounting around 80% subjects. Nonetheless, insufficiency trustworthy molecular markers remains a significant challenge HCC diagnosis treatment evaluation. HCC, such MEG3, MALAT1, HULC, HOTAIR, H19 dysregulation closely associated with expansion, metastasis, prognosis, diagnosis. primary goal this investigation was investigate newly discovered roles mechanisms pathophysiology cells identify potential therapeutic targets.

Language: Английский

Citations

4
RNF2 induces myeloid-derived suppressor cells chemotaxis and promotes hepatocellular carcinoma progression through the TRAF2-NF-κB signaling axis DOI Creative Commons

Manman Liang,

Jianghua Yang, Aiping Zhang

et al.

Cancer Immunology Immunotherapy, Journal Year: 2025, Volume and Issue: 74(5)

Published: March 27, 2025

Language: Английский

Citations

0
Multi-omics Analysis Revealed the Diagnostic and Therapeutic Value of Immunogenic Cell Death-derived SCN5A in Hepatocellular Carcinoma DOI

Zicheng Liang,

Wei Tan, Xiangdong Fang

et al.

Molecular Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Language: Английский

Citations

0
Apigenin as a Promising Agent for Enhancing Female Reproductive Function and Treating Associated Disorders DOI Creative Commons
Alexander V. Sirotkin, Abdel Halim Harrath

Biomedicines, Journal Year: 2024, Volume and Issue: 12(10), P. 2405 - 2405

Published: Oct. 21, 2024

Apigenin is an organic flavonoid abundant in some plants such as parsley, chamomile, or celery. Recently, it has been investigated for several of its pharmacological characteristics, ability to act antioxidant, reduce inflammation, and inhibit the growth cancer cells. The purpose this review provide a summary existing knowledge regarding effects apigenin on female reproductive systems dysfunctions. can influence processes by regulating multiple biological events, including oxidative processes, cell proliferation, apoptosis, renewal viability, ovarian blood supply, release hormones. It could stimulate folliculogenesis, well embryonal proliferation which lead increase fertility hormones, may exert health. Furthermore, activities cells alleviate pathological changes system caused environmental pollutants, harmful medications, cancer, polycystic syndrome, ischemia, endometriosis. Therefore, have potential biostimulator therapeutic agent certain diseases.

Language: Английский

Citations

1
Siling Decoction Ameliorates Adenine-Induced Renal Fibrosis in Rats by the AKT/IKKβ/NFκB Signaling Pathway DOI
Lianlin Zeng, Yu‐Chuan Lin, Haixu Chen

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156228 - 156228

Published: Nov. 8, 2024

Language: Английский

Citations

0