NSG2: a promising prognostic marker shaping the immune landscape of breast cancer DOI Creative Commons
Xuan Li,

Qihai Gu,

Ping‐Ping Sun

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 18, 2024

Breast cancer (BC) remains a significant health issue globally and most common cause of mortality in women. Enhancing our understanding on biomarkers may greatly improve both diagnostic therapeutic approaches to this disease.

Language: Английский

Ferroptosis and immunosenescence in colorectal cancer DOI
Yao Wang, Xinran Cao,

Chunbaixue Yang

et al.

Seminars in Cancer Biology, Journal Year: 2024, Volume and Issue: 106-107, P. 156 - 165

Published: Oct. 16, 2024

Language: Английский

Citations

10
Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors DOI Creative Commons
Elena Catanzaro, Manuel Beltrán‐Visiedo, Lorenzo Galluzzi

et al.

Cellular and Molecular Immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

While immunotherapy with immune checkpoint inhibitors (ICIs) has revolutionized the clinical management of various malignancies, a large fraction patients are refractory to ICIs employed as standalone therapeutics, necessitating development combinatorial treatment strategies. Immunogenic cell death (ICD) inducers have attracted considerable interest partners for ICIs, at least in part owing their ability initiate tumor-targeting adaptive response. However, compared either approach alone, regimens involving ICD and not always shown superior activity. Here, we discuss accumulating evidence on therapeutic interactions between oncological settings, identify key factors that may explain discrepancies preclinical findings, propose strategies address existing challenges increase efficacy these combinations cancer.

Language: Английский

Citations

8
Prodrug-based combinational nanomedicine remodels lipid metabolism for reinforced ferroptosis and immune activation DOI Creative Commons
Ling Lin,

Zaixiang Fang,

Guohao Liu

et al.

Acta Pharmaceutica Sinica B, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Sodium butyrate increases USP5-mediated ubiquitination degradation of GPX4 and enhances anti-cancer efficacy of anti-PD-1 antibody DOI

Qimeng Chang,

Huarong Mao,

Jin-Feng Feng

et al.

Biochemical Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 116927 - 116927

Published: April 1, 2025

Language: Английский

Citations

0
NSG2: a promising prognostic marker shaping the immune landscape of breast cancer DOI Creative Commons
Xuan Li,

Qihai Gu,

Ping‐Ping Sun

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 18, 2024

Breast cancer (BC) remains a significant health issue globally and most common cause of mortality in women. Enhancing our understanding on biomarkers may greatly improve both diagnostic therapeutic approaches to this disease.

Language: Английский

Citations

1