Microbial Cell Factories,
Journal Year:
2019,
Volume and Issue:
18(1)
Published: Oct. 15, 2019
Yarrowia
lipolytica
is
an
unconventional
yeast
with
a
huge
industrial
potential.
Despite
many
advantages
for
biotechnological
applications,
it
possesses
enormous
demand
oxygen,
which
bottleneck
in
large
scale
production.
In
this
study
codon
optimized
bacterial
hemoglobin
from
Vitreoscilla
stercoraria
(VHb)
was
overexpressed
Y.
efficient
growth
and
erythritol
synthesis
glycerol
low-oxygen
conditions.
Erythritol
natural
sweetener
produced
by
under
high
osmotic
pressure
at
low
pH,
process
requires
oxygen
demand.Under
these
conditions
the
VHb
overexpressing
strain
showed
mostly
yeast-type
cells
resulting
83%
higher
titer
shake-flask
experiments.
During
bioreactor
engineered
productivity
(QERY
=
0.38
g/l
h)
yield
(YERY
0.37
g/g)
comparison
to
control
0.30
h,
YERY
0.29
g/g).
Moreover,
stirring
during
fermentation
resulted
modest
foam
formation.This
that
overexpression
of
allows
dynamic
production
value-added
product
low-value
substrate.
Biotechnology and Applied Biochemistry,
Journal Year:
2021,
Volume and Issue:
69(6), P. 2794 - 2818
Published: Jan. 23, 2021
Abstract
Glycerol
is
a
common
by‐product
of
industrial
biodiesel
syntheses.
Due
to
its
properties,
availability,
and
versatility,
residual
glycerol
can
be
used
as
raw
material
in
the
production
high
value‐added
inputs
outputs.
In
particular,
products
like
hydrogen,
propylene
glycol,
acrolein,
epichlorohydrin,
dioxalane
dioxane,
carbonate,
n
‐butanol,
citric
acid,
ethanol,
butanol,
propionic
(mono‐,
di‐,
triacylglycerols),
cynamoil
esters,
acetate,
benzoic
other
applications.
this
context,
present
study
presents
critical
evaluation
innovative
technologies
based
on
use
different
industries,
including
pharmaceutical,
textile,
food,
cosmetic,
energy
sectors.
Chemical
biochemical
catalysts
transformation
are
explored,
along
with
factors
considered
regarding
choice
catalyst
route
conversion
process,
aiming
at
improving
these
products.
Molecules,
Journal Year:
2023,
Volume and Issue:
29(1), P. 22 - 22
Published: Dec. 19, 2023
Citric
acid
finds
broad
applications
in
various
industrial
sectors,
such
as
the
pharmaceutical,
food,
chemical,
and
cosmetic
industries.
The
bioproduction
of
citric
uses
microorganisms,
but
most
commonly
employed
ones
are
filamentous
fungi
Aspergillus
niger
yeast
Yarrowia
lipolytica.
This
article
presents
a
literature
review
on
properties
acid,
microorganisms
substrates
used,
different
fermentation
techniques,
its
utilization,
global
market.
emphasizes
that
there
is
still
much
to
explore,
both
terms
production
process
techniques
emerging
new
acid.
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
261, P. 129536 - 129536
Published: Jan. 24, 2024
With
the
rapid
development
of
biodiesel,
biodiesel-derived
glycerol
has
become
a
promising
renewable
bioresource.
The
key
to
utilizing
this
bioresource
lies
in
value-added
conversion
crude
glycerol.
While
purifying
into
pure
form
allows
for
diverse
applications,
intricate
nature
process
renders
it
costly
and
environmentally
stressful.
Consequently,
technology
facilitating
direct
utilization
unpurified
holds
significant
importance.
It
been
reported
that
can
be
bio-transformed
or
chemically
converted
high-value
polymers.
These
technologies
provide
cost-effective
alternatives
polymer
production
while
contributing
more
sustainable
biodiesel
industry.
This
review
article
describes
global
quality
characteristics
investigates
influencing
factors
treatment
composition
including
water,
methanol,
soap,
matter
organic
non-glycerol,
ash.
Additionally,
also
focused
on
advantages
challenges
various
converting
polymers,
considering
such
as
compatibility
control
unfavorable
factors.
Lastly,
application
prospect
value
were
discussed
from
aspects
economy
environmental
protection.
new
increased
use
feedstock
will
facilitated
by
findings
review,
promoting
mass
market
applications.
Fermentation,
Journal Year:
2021,
Volume and Issue:
7(2), P. 50 - 50
Published: April 3, 2021
The
agri-food
industry
annually
produces
huge
amounts
of
crops
residues
and
wastes,
the
suitable
management
these
products
is
important
to
increase
sustainability
agro-industrial
production
by
optimizing
entire
value
chain.
This
also
in
line
with
driving
principles
circular
economy,
according
which
can
become
feedstocks
for
novel
processes.
Oleaginous
yeasts
represent
a
versatile
tool
produce
biobased
chemicals
intermediates.
They
are
flexible
microbial
factories
able
grow
on
different
side-stream
carbon
sources
such
as
those
deriving
from
this
characteristic
makes
them
excellent
candidates
integrated
biorefinery
processes
through
lipids,
known
single
cell
oils
(SCOs),
applications.
review
aims
present
an
extensive
overview
research
progress
use
oleaginous
discussions
current
bottlenecks
perspectives
their
exploitation
sectors,
foods,
biofuels
fine
chemicals.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(7), P. 2300 - 2300
Published: April 1, 2022
Yarrowia
lipolytica,
an
oleagineous
species
of
yeast,
is
a
carrier
various
important
nutrients.
The
biomass
this
yeast
extensive
source
protein,
exogenous
amino
acids,
bioavailable
essenctial
trace
minerals,
and
lipid
compounds
as
mainly
unsaturated
fatty
acids.
also
contains
B
vitamins,
including
vitamin
B12,
many
other
bioactive
components.
Therefore,
Y.
lipolytica
can
be
used
in
food
supplements
for
humans
safe
nutritional
additives
maintaining
the
homeostasis
organism,
vegans
vegetarians,
athletes,
people
after
recovery,
at
risk
deficiencies.
