Published: June 9, 2022
A Rafa y Noe,
Biosensors and Bioelectronics, Journal Year: 2022, Volume and Issue: 213, P. 114454 - 114454
Published: June 8, 2022
Language: Английский
Citations
32
ECS Sensors Plus, Journal Year: 2022, Volume and Issue: 1(2), P. 021601 - 021601
Published: April 7, 2022
Multiplex biomarker quantitation is ideal for tracking the progression of a disease, but sensitive, specific, and quantitative multiplex biosensing remains challenging. We achieved total internal reflection with two lasers in single planar optical waveguide by coupling 532 nm laser light into diffraction grating 635 directly thin film same waveguide. confirmed that evanescent fields generated can excite fluorescent dyes (Alexa Fluor Alexa 647) held to surface through biotin-streptavidin chemistry. This sensing concept holds significant potential as platform detection.
Language: Английский
Citations
23
Food Control, Journal Year: 2023, Volume and Issue: 152, P. 109892 - 109892
Published: May 29, 2023
Language: Английский
Citations
13
Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(33), P. 12521 - 12531
Published: Aug. 9, 2023
There remains an unmet need for a fully integrated microfluidic platform that can automatically perform multistep and multireagent immunoassays. Here, we proposed novel online dual-active valve-based centrifugal chip, termed DAVM, automatic point-of-care immunoassay. Practically, the puncture valve, one of dual active valves, is capable achieving precise, on-demand, sequential release prestored reagents, while other valve-reversible valve enables controlled retention drainage reaction solutions. Thereby, our technology mitigates challenges hydrophilic/hydrophobic modifications unstable control performance commonly observed in passive controls. As proof concept, indirect enzymatic immunoblotting technique was employed on DAVM automated immunological analysis eight targets, yielding outcomes within hour. Furthermore, conducted comparative 28 clinical samples with autoimmune diseases. According to 224 data, sample testing concordance rate between traditional instrument 82%, target compliance 97%. Therefore, system has powerful potential
Language: Английский
Citations
13
Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: 427, P. 137185 - 137185
Published: Jan. 5, 2025
Language: Английский
Citations
0
Biosensors and Bioelectronics, Journal Year: 2022, Volume and Issue: 208, P. 114193 - 114193
Published: March 31, 2022
The ongoing emergence of severe acute respiratory syndrome caused by the new coronavirus (SARS-CoV-2) variants requires swift actions in identifying specific antigens and optimizing vaccine development to maximize humoral response patient. Measuring specificity amount antibody produced host immune system with high throughput accuracy is critical develop timely diagnostics therapeutic strategies. Motivated finding an easy-to-use cost-effective alternative existing serological methodologies for multiplex analysis, we a proof-of-concept nanoplasmonic biosensor capture serums against multiple antigens. Nanoplasmonic sensing relies on wavelength shift localized surface plasmon resonance (LSPR) peak gold nanostructures upon binding interactions between antibodies immobilized Here are first different areas using mono-biotinylation based affinity interaction biotin streptavidin. We then validate platform detecting presence 3 monoclonal (2 hemagglutinins (HAs) from influenza viruses, SARS-CoV-2 Spike RBD (receptor domain)). also measure murine sera collected before after its immunization protein, good agreement results obtained ELISA assay. Our assays have successfully demonstrated serum profiling, which can be further integrated microfluidics as effective screening future studies development.
Language: Английский
Citations
17
Reviews in Agricultural Science, Journal Year: 2024, Volume and Issue: 12(0), P. 128 - 146
Published: Jan. 1, 2024
Pesticides are essential for agriculture, but because of their residues in crops, produce and soil, they have become a major concern. Traditional pesticide detection methods, particularly gas chromatography-mass spectrometry, expensive impractical small-scale farmers. Recognizing the need robust yet accessible sensing researchers attempted to develop sensors that use various mechanisms. Biosensors made significant progress by utilizing biochemical mechanisms detect trace amounts pesticides. However, limitations single or specific chemical class driven exploration innovative approaches. This review covers range biosensor receptor transducer highlights recent advancements technologies. The focus is on integrating modern data-processing specifically Sensor arrays such as electronic noses (e-noses) tongues (e-tongues) explored, along with an in-depth analysis sensor incorporating machine learning other techniques. explores potential advanced data processing methods effectively analyze raw from arrays, ultimately enriching
Language: Английский
Citations
3
Nanoscale, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
This paper provides a comprehensive review of the latest research advancements in overcoming Debye screening effect field-effect transistor (FET) sensors.
Language: Английский
Citations
3
Food Chemistry, Journal Year: 2022, Volume and Issue: 404, P. 134570 - 134570
Published: Oct. 12, 2022
Language: Английский
Citations
11
Analytica Chimica Acta, Journal Year: 2021, Volume and Issue: 1173, P. 338656 - 338656
Published: May 25, 2021
Language: Английский
Citations
11