Micromachines,
Journal Year:
2022,
Volume and Issue:
13(4), P. 631 - 631
Published: April 16, 2022
Metamaterial
biosensors
have
been
extensively
used
to
identify
cell
types
and
detect
concentrations
of
tumor
biomarkers.
However,
the
methods
for
in
situ
non-destruction
measurement
migration,
which
plays
a
key
role
progression
metastasis,
are
highly
desirable.
Therefore,
flexible
terahertz
metamaterial
biosensor
based
on
parylene
C
substrate
was
proposed
label-free
non-destructive
detection
breast
cancer
growth
migration.
The
maximum
resonance
peak
frequency
shift
achieved
183.2
GHz
when
MDA-MB-231
cultured
onto
surface
72
h.
A
designed
polydimethylsiloxane
(PDMS)
barrier
sheet
applied
rate
quantified
as
14.9
µm/h.
experimental
expressed
linear
relationship
with
covered
area
quadratic
distance,
consistent
simulation
results.
Additionally,
migration
indicated
that
transform
factor-β
(TGF-β)
promoted
shows
great
potential
investigation
biology
future.
iScience,
Journal Year:
2022,
Volume and Issue:
25(2), P. 103799 - 103799
Published: Jan. 21, 2022
Terahertz
(THz)
electromagnetic
spectrum
ranging
from
0.1THz
to
10THz
has
become
critical
for
sixth
generation
(6G)
applications,
such
as
high-speed
communication,
fingerprint
chemical
sensing,
non-destructive
biosensing,
and
bioimaging.
However,
the
limited
response
of
naturally
existing
materials
THz
waves
induced
a
gap
in
spectrum,
where
lack
functional
devices
using
natural
occurred
this
gap.
Metamaterials,
artificially
composed
structures
that
can
engineer
properties
manipulate
waves,
have
enabled
development
many
devices,
known
"metadevices".
Besides,
tunability
metadevices
be
achieved
by
tunable
microelectromechanical
system
(MEMS)
technologies,
well
including
phase
change
(PCMs),
electro-optical
(EOMs),
thermo-optical
(TOMs).
Leveraging
various
tuning
mechanisms
together
with
metamaterials,
tremendous
research
works
demonstrated
reconfigurable
playing
an
important
role
fill
toward
6G
applications.
This
review
introduces
fundamental
principles
metamaterial
resonant
design
their
related
Moreover,
we
provide
perspectives
on
future
photonic
state-of-the-art
IEEE Access,
Journal Year:
2023,
Volume and Issue:
11, P. 18590 - 18619
Published: Jan. 1, 2023
There
is
a
keen
interest
in
the
exploration
of
new
generation
emitters
and
detectors
due
to
advancements
innovation
materials
device
processing
technologies
which
have
opened
up
frontiers
Terahertz
(THz)
spectrum.
Therefore,
it
necessary
review
developments
THz
technology
for
healthcare
applications,
their
impact,
implications
prospects
ongoing
research
development.
This
paper
provides
broad
overview
current
status
application
imaging
sensing
domain.
We
present
knowledge,
identify
existing
challenges
wide
scale
clinical
adoption
systems
prospective
opinions
facilitate
development
towards
optimized
miniaturized
biosensors
that
provide
real
operational
convenience
through
emerging
trends.
Firstly,
we
an
techniques
exploit
properties
detection
with
emphasis
on
terahertz
time
domain
spectroscopy
(THz-TDS)
Metamaterials.
The
mechanisms
tissue
image
contrast
biomedical
applications
particular,
cancer
reported.
Secondly,
outlook
toward
interface
4.0
its
enabling
explored
next
smart
connected
systems.
Third,
merits
suggest
pave
way
future
research.
Further,
discuss
recent
advances
contribution
near-field
based
plasmonic,
resonance
metasurfaces,
waveguides
etc.
breaking
diffraction
limit
are
convenient
point
care.
bring
researchers
roadmap
scope.
Frontiers in Oncology,
Journal Year:
2022,
Volume and Issue:
11
Published: Jan. 19, 2022
In
recent
years,
the
morbidity
and
mortality
of
gastrointestinal
cancer
have
remained
high
in
China.
Due
to
deep
location
organs,
such
as
gastric
cancer,
early
symptoms
are
not
obvious.
It
is
generally
discovered
at
an
advanced
stage
with
distant
metastasis
lymph
node
infiltration,
making
it
difficult
cure.
Therefore,
there
a
significant
need
for
novel
technologies
that
can
effectively
diagnose
treat
ultimately
reducing
its
mortality.
Gold
nanoparticles
(GNPs),
type
nanocarrier
unique
optical
properties
remarkable
biocompatibility,
potential
influence
fate
by
delivering
drugs,
nucleic
acids
cells
tissues.
As
safe
reliable
visualization
agent,
GNPs
track
drugs
accurately
indicate
boundaries
opening
up
new
possibilities
treatment.
addition,
been
used
photodynamic
therapy
deliver
photosensitizers,
well
combination
photothermal
therapy.
be
effective
nanomaterial
treatment
diagnosis
cancer.
Small Methods,
Journal Year:
2022,
Volume and Issue:
6(10)
Published: Sept. 6, 2022
Abstract
Field
effect
transistor
(FET)‐based
nanoelectronic
biosensor
devices
provide
a
viable
route
for
specific
and
sensitive
detection
of
cancer
biomarkers,
which
can
be
used
early
stage
detection,
monitoring
the
progress
disease,
evaluating
effectiveness
therapies.
On
road
to
implementation
FET‐based
in
diagnostics,
several
key
issues
need
addressed:
sensitivity,
selectivity,
operational
conditions,
anti‐interference,
reusability,
reproducibility,
disposability,
large‐scale
production,
economic
viability.
To
address
these
well‐known
issues,
significant
research
efforts
have
been
made
recently.
An
overview
is
provided
here,
highlighting
approaches
strategies
presently
engaged
at
each
developmental
stage,
from
design
fabrication
performance
evaluation
data
analysis.
Specifically,
this
review
discusses
multistep
FETs,
choice
bioreceptors
relevant
measurement
configuration,
outlines
improve
sensing
reach
level
required
clinical
applications.
Finally,
expected
future
generation
diagnostic
their
potential
biomarkers
as
well
other
noncommunicable
communicable
diseases.
The Analyst,
Journal Year:
2022,
Volume and Issue:
147(15), P. 3396 - 3414
Published: Jan. 1, 2022
Rolling
circle
amplification
(RCA)
is
a
simple
and
isothermal
DNA
technique
that
used
to
generate
thousands
of
repeating
sequences
using
circular
templates
under
the
catalysis
polymerase.
