ACS ES&T Water,
Journal Year:
2023,
Volume and Issue:
3(8), P. 2318 - 2327
Published: June 7, 2023
Excessive
use
of
antibiotics
causes
their
residues
in
the
environment
and
food,
seriously
threatening
ecosystem
human
health.
Designing
a
portable
sensitive
sensor
for
on-site
analysis
is
therefore
high
demand.
In
this
study,
we
have
developed
smartphone-capable
hydrogel
colorimetric
platform
ultrasensitive
detection
kanamycin
(KAN)
based
on
aptamer-regulated
nanozyme
activity.
The
synthesized
Fe/CeO2
hexagonal
bipyramidal
microcrystals
(Fe/CeO2
HBs)
exhibited
excellent
peroxidase-like
activity,
but
it
could
be
obviously
inhibited
by
aptamer,
inhibition
effect
was
further
enhanced
with
specific
recognition
between
target
making
possible
to
design
facile
method
KAN
analysis.
Moreover,
aptamer-functionalized
HBs
HBs@Apt)
were
introduced
into
fabricate
analytical
tube,
whose
signal
read
out
smartphone
platform,
realizing
KAN.
linear
response
range
0.05–48.45
ng
mL–1
an
ultralow
limit
0.035
recovery
rate
ranging
from
99.57
103.76%
spiked
real
samples,
demonstrating
its
superior
accuracy
reliability.
This
work
provides
new
insights
designing
solid-phase
hydrogel-based
antibiotic
residues.
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(17), P. 21239 - 21251
Published: April 18, 2023
The
development
of
artificial
nanozymes
with
superior
catalytic
performance
and
excellent
stability
has
been
a
long-standing
objective
for
chemists.
total
antioxidant
capacity
(TAC)
is
one
the
most
important
bioanalytical
measures
oxidative
stress
in
body.
present
work
aims
to
develop
smartphone-assisted
visual
detection
sensor
using
cerium-doped
strontium-based
metal-organic
frameworks
(Ce-SrMOFs)
as
peroxidase-like
rapid,
low-cost,
on-site
TAC.
pristine
SrMOF
functioned
peroxidase
nanozyme,
its
enzymatic
activity
was
enhanced
after
doping
it
Ce(IV)
ions
because
multivalent
nature
synergistic
impact
heteroatoms.
Ce-SrMOFs
were
sensitive
single
electron
transfer
hydrogen
atom
processes,
which
implies
that
can
serve
an
ideal
nanozyme
candidate
TAC
analysis.
investigated
mechanism
revealed
•OH
active
oxygen
species
activity.
exhibited
strong
affinity
3,3',5,5'-tetramethylbenzidine
(TMB)
H2O2,
Km
values
0.082
0.427
mM,
are
5.29-
8.67-fold
lower
than
those
horseradish
(HRP),
respectively.
used
ascorbic
acid,
cysteine,
glutathione,
limits
44,
53,
512
nM,
proposed
method
proved
effective
measuring
saliva
samples
from
lung
cancer
patients,
thereby
yielding
results
satisfactory
precision
accuracy.
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(5), P. 6473 - 6485
Published: Jan. 31, 2023
The
residues
of
organophosphorus
pesticides
(OPs)
have
drawn
worldwide
increasing
attention
because
their
potential
fatal
effects
on
human
health
and
ecological
systems.
It
is
great
significance
to
develop
an
efficient
portable
method
for
in-field
detection
OPs.
Herein,
a
novel
core-shell
nanocomposite
prussian
blue@Fe-covalent
organic
framework@Au
(PB@Fe-COF@Au)
was
constructed.
Fe2+
Fe3+
in
PB
nanoparticle
(PBNP)
cores,
Fe-porphyrin
COF
shells,
AuNPs
grown
shells
all
acted
as
peroxidase-like
catalytic
active
sites,
enabling
PB@Fe-COF@Au
possess
triplet
activity.
A
colorimetric,
affordable,
sensitive,
selective
strategy
designed
detect
Compared
with
previous
reports,
this
sensor
realized
wider
linear
range
chlorpyrifos
10-800
ng
mL-1
relatively
lower
limit
0.61
mL-1,
which
attributed
the
overlapping
triple
sites
response
assay
successfully
employed
food
environmental
samples.
Moreover,
meet
demand
OPs,
spherical
hydrogel
based
visual,
portable,
equipment-free
features
fabricated.
This
work
provides
new
pathway
design
apply
effective
nanozymes
on-site
monitoring
pesticides.
Environmental Science Nano,
Journal Year:
2024,
Volume and Issue:
11(3), P. 766 - 796
Published: Jan. 1, 2024
Here
we
made
a
critical
review
on
nanozyme-involved
detection
and
degradation
of
environmental
pollutants,
the
research
progress
achieved
in
last
five
years
was
emphatically
concluded.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(3), P. 314 - 314
Published: Feb. 24, 2023
Nanozymes
are
nanomaterials
with
enzyme-like
activity,
possessing
the
unique
properties
of
and
natural
catalytic
functions.
catalytically
active,
stable,
tunable,
recyclable,
versatile.
Therefore,
increasing
attention
has
been
paid
in
fields
environmental
science
life
sciences.
In
this
review,
we
focused
on
most
recent
applications
nanozymes
for
monitoring,
management,
protection.
We
firstly
introduce
tuning
activity
according
to
some
crucial
factors
such
as
size
shape,
composition
doping,
surface
coating.
Then,
application
introduced
detail.
can
not
only
be
used
detect
inorganic
ions,
molecules,
organics,
foodborne
pathogenic
bacteria
but
also
involved
degradation
phenolic
compounds,
dyes,
antibiotics.
The
capability
was
reported
assisting
air
purification,
constructing
biofuel
cells,
marine
antibacterial
fouling
removal.
Finally,
current
challenges
future
trends
toward
proposed
discussed.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 13, 2024
Abstract
As
nanoscale
materials
with
the
function
of
catalyzing
substrates
through
enzymatic
kinetics,
nanozymes
are
regarded
as
potential
alternatives
to
natural
enzymes.
Compared
protein‐based
enzymes,
exhibit
attractive
characteristics
low
preparation
cost,
robust
activity,
flexible
performance
adjustment,
and
versatile
functionalization.
These
advantages
endow
them
wide
use
from
biochemical
sensing
environmental
remediation
medical
theranostics.
Especially
in
biomedical
diagnosis,
feature
catalytic
signal
amplification
provided
by
makes
emerging
labels
for
detection
biomarkers
diseases,
rapid
developments
observed
recent
years.
To
provide
a
comprehensive
overview
progress
made
this
dynamic
field,
here
an
diagnosis
enabled
is
provided.
This
review
first
summarizes
synthesis
nanozyme
then
discusses
main
strategies
applied
enhance
their
activity
specificity.
Subsequently,
representative
utilization
combined
biological
elements
disease
reviewed,
including
related
metabolic,
cardiovascular,
nervous,
digestive
diseases
well
cancers.
Finally,
some
development
trends
nanozyme‐enabled
highlighted,
corresponding
challenges
also
pointed
out,
aiming
inspire
future
efforts
further
advance
promising
field.
