Advances and Future Trends in Nanozyme-Based SERS Sensors for Food Safety, Environmental and Biomedical Applications

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 709 - 709

Published: Jan. 15, 2025

Nanozymes, a kind of nanoparticles with enzyme-mimicking activities, have attracted considerable attention due to their robust catalytic properties, ease preparation, and resistance harsh conditions. By combining nanozymes surface-enhanced Raman spectroscopy (SERS) technology, highly sensitive selective sensors been developed. These are capable detecting wide range analytes, such as foodborne toxins, environmental pollutants, biomedical markers. This review provides an overview recent advancements in the synthesis surface modification nanozymes, highlighting ability mimic multiple enzymes enhance performance. In addition, we explore development applications nanozyme-based SERS food contaminants, The concludes perspectives challenges facing field, involving need for deeper understanding nanozyme principles mechanisms, standardized systems characterization, engineering tailored properties specific applications. Finally, discuss potential integrating various techniques create multi-modal detection platforms, paving way next generation analytical tools fields safety, monitoring, diagnostics.

Language: Английский

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Kinetics Difference-driven Organophosphorus Hydrolase-like Nanozyme-Coded Pattern for Identifying p-Nitrophenyl Pesticides

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Organophosphorus pesticides (OPs) are widely used in agricultural production, posing a great threat to human health and the environment. Given that different OPs present toxicology toxicities, identifying individual pesticide residues becomes important for assessing food safety environmental implications. In this work, kinetics difference-driven analyte hydrolysis strategy is proposed first time validated identify p-nitrophenyl by developing an organophosphorus hydrolase-like nanozyme-coded sensor array. Ultrasmall bare CeO2 nanoparticles were synthesized employed as only sensing unit catalyze of multiple analytes. With catalytic preferences differences under identical reaction conditions, five common analogues (methyl-paraoxon, paraoxon, methyl-parathion, parathion, fenitrothion) offered discriminable colors. By coupling color fingerprints with pattern recognition, accurate identification their mixtures at variety concentrations ratios was verified laboratory practical scenarios. Attractively, apart from excellent performance convenient operation, hydrolytic presents strong resistance against redox substances often cause interference previous oxidoreductase-based arrays. Our study provides new paradigm discriminating specific precisely, showing promising applications multitarget analysis complex matrices.

Language: Английский

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A Programmable Microfluidic Paper-Based Analytical Device for Simultaneous Colorimetric and Photothermal Visual Sensing of Multiple Enzyme Activities

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(29), P. 12181 - 12188

Published: July 8, 2024

New strategies for the simultaneous and portable detection of multiple enzyme activities are highly desirable clinical diagnosis home care. However, methods developed thus far generally suffer from high costs, cumbersome procedures, heavy reliance on large-scale instruments. To satisfy actual requirements rapid, accurate, on-site activities, we report herein a smartphone-assisted programmable microfluidic paper-based analytical device (μPAD) that utilizes colorimetric photothermal signals simultaneous, visual quantitative alkaline phosphatase (ALP) butyrylcholinesterase (BChE). Specifically, operation this μPAD sensing platform is based two sequential steps. Cobalt-doped mesoporous cerium oxide (Co-m-CeO

Language: Английский

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Redox interference-free bimodal paraoxon sensing enabled by an aggregation-induced emission nanozyme catalytically hydrolyzing phosphoesters specifically

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 267, P. 116756 - 116756

Published: Sept. 6, 2024

Language: Английский

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Regulating the redox and non-redox enzyme-mimicking activities of Ce-UiO-66-NO2 nanozyme for dual-mode sensing of phosphate

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 412, P. 135782 - 135782

Published: April 9, 2024

Language: Английский

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Carbon-based nanozymes: design, catalytic mechanisms, and environmental applications

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(27), P. 5949 - 5964

Published: June 25, 2024

Language: Английский

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Silicon-based bimetallic nanozyme-enhanced immunochromatographic strips for highly sensitive simultaneous detection of multiple environmental pollutants

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159936 - 159936

Published: Jan. 1, 2025

Language: Английский

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A review on waste derived carbon nanozyme: An emerging catalytic material for monitoring and degrading environmental pollutants

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160762 - 160762

Published: Feb. 1, 2025

Language: Английский

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Recent trends and sources of lead toxicity: a review of state-of-the-art nano-remediation strategies

Journal of Nanoparticle Research, Journal Year: 2024, Volume and Issue: 26(7)

Published: July 1, 2024

Language: Английский

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Ligand density-optimized peroxidase-like activity of gold nanoclusters for colorimetric sensing of biothiols and acetylcholinesterase

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 417, P. 136069 - 136069

Published: June 4, 2024

Language: Английский

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