Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Microsystems & Nanoengineering, Journal Year: 2024, Volume and Issue: 10(1)
Published: May 22, 2024
Abstract The development of artificial intelligence-enabled medical health care has created both opportunities and challenges for next-generation biosensor technology. Proteins are extensively used as biological macromolecular markers in disease diagnosis the analysis therapeutic effects. Electrochemical protein biosensors have achieved desirable specificity by using specific antibody–antigen binding principle immunology. However, active centers biomarkers surrounded a peptide matrix, which hinders charge transfer results insufficient sensor sensitivity. Therefore, electrode-modified materials transducer devices been designed to increase sensitivity improve practical application prospects electrochemical sensors. In this review, we summarize recent reports biomarker detection. We highlight latest research on detection cancer, viral infectious diseases, inflammation, other diseases. corresponding sensitive materials, structures, principles associated with such also addressed generally. Finally, present an outlook use marker next few years.
Language: Английский
Citations
21
Soft Science, Journal Year: 2024, Volume and Issue: 4(3)
Published: July 8, 2024
Skin is a rich source of invaluable information for healthcare management and disease diagnostics. The integration soft skin electronics enables precise timely capture these cues at the interface. Leveraging attributes such as lightweight design, compact size, high integration, biocompatibility, enhanced comfort, technologies hold significant promise advancing various applications. However, fabrication process most existing typically requires expensive platforms clean-room environments, potentially inflating production costs. In recent years, emergence laser-induced-graphene (LIG) has presented practical solution developing that are both cost-effective high-performing. This advancement paves way widespread adoption intelligent technologies. Here, we comprehensively review studies focusing on LIG-based (LIGS2E) We first outline preparation methodologies, fundamental properties LIG, standard regulation strategies employed in electronics. Subsequently, present an overview LIGS2E designs their diverse applications healthcare. These encompass biophysical biochemical sensors, bio-actuators, power supply systems. Finally, deliberate potential challenges associated with implementation settings offer insights into future directions research development. By elucidating capabilities limitations LIGS2E, this aims to contribute
Language: Английский
Citations
13
Critical Reviews in Clinical Laboratory Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 30
Published: Feb. 1, 2025
Monitoring individuals' laboratory data is essential for assessing their health status, evaluating the effectiveness of treatments, predicting disease prognosis and detecting subclinical conditions. Currently, monitoring performed intermittently, measuring serum, plasma, whole blood, urine occasionally other body fluids at predefined time intervals. The ideal approach entails continuous measurement concentration activity biomolecules in all fluids, including solid tissues. This can be achieved through use biosensors strategically placed various locations on human where measurements are required monitoring. High-tech wearable provide an ideal, noninvasive, esthetically pleasing solution data. However, despite significant advances biosensor technology, capacities number different analytes that continuously monitored patients not yet desired level. In this review, we conducted a literature search examined: (i) overview background personalized medicine, (ii) used individuals, (iii) types methods biomolecules, (iv) statistical algorithms analysis interpretation evaluation.
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 155808 - 155808
Published: Sept. 1, 2024
Language: Английский
Citations
6
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156110 - 156110
Published: Sept. 1, 2024
Language: Английский
Citations
4
Electroanalysis, Journal Year: 2025, Volume and Issue: 37(2)
Published: Feb. 1, 2025
Bisphenol A (BPA) exposure poses significant health risks, making its analysis essential. This study presents a portable electrochemical sensing platform using copper nanoparticles (CuNPs) decorated on laser‐induced graphene (LIG) electrode (CuNPs@LIGE). The is created through one‐step synthesis that combines polyimide and metal precursors, resulting in three‐dimensional porous structure. sensor utilizes linear scan voltammetry for BPA detection with smartphone‐connected workstation. presence of CuNPs LIG enhances electrical conductivity response signals. Under optimal conditions, the achieves range from 0.1 μmol/L to 10.0 mmol/L low limit 0.033 (3 σ ), demonstrating good stability selectivity. Additionally, it shows recovery rates between 95.71% 99.17% seawater samples, strong candidate rapid monitoring applications.
Language: Английский
Citations
0
Advanced Sensor Research, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 15, 2025
Abstract Phosphorylated proteins in human sweat are found to be closely associated with neurodegenerative diseases, including Alzheimer's disease. Real‐time, non‐invasive detection of changes the types and levels phosphorylated is significant clinical value for prevention diagnosis these diseases. This research introduces an electrochemical sensor based on situ‐grown interpenetrating network structure UiO‐66‐NH 2 /MWCNTs‐OH, specifically designed detecting sweat. The tested common non‐phosphorylated proteins, demonstrating excellent selectivity, repeatability, reproducibility, stability, a limit as low 0.28 µmol L −1 . Additionally, biotoxicity experiments conducted SD rats volunteers show that /MWCNTs‐OH biologically safe, making it suitable use biosensor. Finally, fabrication sensing module provides foundation development subsequent wearable sensors.
Language: Английский
Citations
0
Advanced Physics Research, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 26, 2025
Abstract Wearable bioelectronics facilitates continuous and efficient monitoring of physiological data, providing real‐time insights personalized medical guidance. However, the reliance on rigid materials in many existing devices restricts flexibility comfort, hindering their seamless integration with soft, dynamic nature human tissue for prolonged on‐body use. 2D carbon‐based nanocomposite hydrogels, renowned tissue‐like elasticity softness, offer immense potential advancing wearable bioelectronics. This review explores synthesis methods performance optimization strategies these innovative materials. It categorizes reinforcement mechanisms nanomaterials, emphasizing improvements mechanical properties, electrical conductivity, multifunctionality. Additionally, it highlights diverse applications hydrogels discusses current challenges future opportunities into flexible bioelectronic devices.
Language: Английский
Citations
0
Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101667 - 101667
Published: March 1, 2025
Language: Английский
Citations
0
Nano-Structures & Nano-Objects, Journal Year: 2025, Volume and Issue: 42, P. 101473 - 101473
Published: April 3, 2025
Language: Английский
Citations
0