Inorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
63(42), P. 19652 - 19664
Published: Oct. 7, 2024
Quantitative
detection
of
tetracycline
(TC)
and
nitrofurantoin
(NFT)
in
food
water
is
importance
for
safety
environmental
protection.
Herein,
Zn2+
was
introduced
into
a
europium
metal–organic
framework
Eu-bpdc
(H2bpdc
=
2,2′-bipyridyl-5,5′-dicarboxylic
acid)
to
prepare
composite
Zn2+@Eu-bpdc,
which
developed
as
fluorescence
sensor
TC
NFT.
The
mechanism
concerns
with
bpdc2–
ligand-to-Eu(III)
charge
transfer,
the
inner
filter
effect.
Zn2+@Eu-bpdc
ratiometric
linear
fitting
equation
I520/I618
1.94
×
104
M–1CTC,
whose
limit
(LOD)
0.148
μmol·L–1
(μM);
it
also
"turn-off"
NFT
(I0–I)/I
3.62
M–1CNFT
LOD
0.0792
μM.
can
detect
or
lake
water,
honey,
milk
high
accuracy.
emission
color
changes
paper-based
depending
on
CTC
CNFT
reveal
visualization
detections
With
red
green
values
input
signals,
smartphone-assisted
on-site
utilized
recognize
antibiotic
residuals
by
self-programmed
APP.
promising
intelligent
platform
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 28, 2025
Abstract
Assembling
natural
proteins
into
large,
strong,
bone‐mimetic
scaffolds
for
repairing
bone
defects
in
large‐animal
load‐bearing
sites
remain
elusive.
Here
this
challenge
is
tackled
by
assembling
pure
silk
fibroin
(SF)
3D
with
cortical‐bone‐like
lamellae,
superior
strength,
and
biodegradability
through
freeze‐casting.
The
unique
lamellae
promote
the
attachment,
migration,
proliferation
of
tissue‐regenerative
cells
(e.g.,
mesenchymal
stem
[MSCs]
human
umbilical
vein
endothelial
cells)
around
them,
are
capable
developing
vitro
cortical‐bone
organoids
a
high
number
MSC‐derived
osteoblasts.
High‐SF‐content
lamellar
scaffolds,
regardless
MSC
inoculation,
regenerated
more
than
non‐lamellar
or
low‐SF‐content
scaffolds.
They
accelerated
neovascularization
transforming
macrophages
from
M1
to
M2
phenotype,
promoting
regeneration
repair
large
segmental
(LSBD)
minipigs
within
three
months,
even
without
growth
factor
supplements.
can
be
further
enhanced
controlling
orientation
lamella
parallel
long
axis
during
implantation.
This
work
demonstrates
power
oriented
bone‐like
protein
LSBD
animal
models.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(28)
Published: July 15, 2024
3D
in
vitro
model
has
emerged
as
a
valuable
tool
for
studying
tissue
development,
drug
screening,
and
disease
modeling.
systems
can
accurately
replicate
microstructures
physiological
features,
mirroring
the
vivo
microenvironment
departing
from
conventional
2D
cell
cultures.
Various
models
utilizing
biomacromolecules
like
collagen
synthetic
polymers
have
been
developed
to
meet
diverse
research
needs
address
complex
challenges
of
contemporary
research.
Silk
proteins,
bearing
structural
functional
similarities
collagen,
increasingly
employed
construct
advanced
systems,
surpassing
limitations
This
review
examines
silk
proteins'
composition,
structure,
properties,
functions,
elucidating
their
role
models.
Furthermore,
recent
advances
biomedical
applications
involving
silk-based
organoid
are
discussed.
In
particular,
unique
attributes
matrix
constituents
constructs
highlighted,
providing
meticulous
evaluation
importance.
Additionally,
it
outlines
current
hurdles
complexities
while
contemplating
future
avenues,
thereby
paving
way
developing
biomimetic
protein-based
microtissues.
Biomaterials Science,
Journal Year:
2024,
Volume and Issue:
12(18), P. 4650 - 4663
Published: Jan. 1, 2024
Upconversion
nanoparticles
(UCNPs)
are
a
class
of
nanomaterials
composed
lanthanide
ions
with
great
potential
for
paraclinical
applications,
especially
in
laboratory
and
imaging
sciences.
UCNPs
have
tunable
optical
properties
the
ability
to
convert
long-wavelength
(low
energy)
excitation
light
into
short-wavelength
(high
emission
ultraviolet
(UV)-visible
near-infrared
(NIR)
spectral
regions.
The
core-shell
structure
can
be
customized
through
chemical
synthesis
meet
needs
different
applications.
surface
also
tailored
by
conjugating
small
molecules
and/or
targeting
ligands
achieve
high
specificity
selectivity,
which
indispensable
elements
biomedical
Specifically,
coatings
enhance
water
dispersion,
biocompatibility,
efficiency
UCNPs,
thereby
optimizing
their
functionality
boosting
performance.
In
this
context,
multimodal
provide
more
accurate
