Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 25, 2024
Among
the
various
aflatoxin
B1
(AFB1)
assays,
performing
accurate
detection
is
difficult
because
false
positives
and
negatives
are
frequent
due
to
limited
sensitivity,
expensive
equipment,
or
inadequate
pretreatment
during
operation.
Here,
an
"off-on"
switch-type
electrochemiluminescence
(ECL)
aptasensor
armed
with
cobalt-sulfur
quantum
dots
was
encapsulated
in
hollow
cobalt-layered
double
hydroxide
nanocages
as
enhanced
luminescent
probe
(Co-LDH@QDs),
a
ferrocene-modified
aptamer
(Fc-APT)
used
quencher.
In
general,
when
Fc-APT
hybridized
complementary
DNA
modified
nanotetrahedron,
electron
transfer
between
ferrocene
Co-LDH@QDs
facilitated,
leading
efficient
quenching
of
ECL
intensity
into
"off"
state
absence
AFB1.
presence
AFB1,
increased
increasing
AFB1
concentration
after
specifically
recognized
that
detached
from
electrode
interface
achieve
"on"
state.
The
linear
range
proposed
for
0.1
pg
mL
Molecules,
Journal Year:
2024,
Volume and Issue:
29(19), P. 4551 - 4551
Published: Sept. 25, 2024
Immunoassays
have
been
widely
used
for
the
determination
of
various
analytes
in
fields
disease
diagnosis,
food
safety,
and
environmental
monitoring.
Dual-signal
immunoassays
are
now
advanced
integrated
detection
technologies
with
excellent
self-correction
self-validation
capabilities.
In
this
work,
we
summarize
recent
advances
development
optical
electrochemical
dual-signal
immunoassays,
including
colorimetric,
fluorescence,
surface-enhanced
Raman
spectroscopy
(SERS),
electrochemical,
electrochemiluminescence,
photoelectrochemical
methods.
This
review
particularly
emphasizes
working
principle
diverse
utilization
dual-functional
molecules
nanomaterials.
It
also
outlines
challenges
prospects
future
research
on
immunoassays.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 2, 2025
Abstract
Organic
photoelectrochemical
transistor
(OPECT)
as
a
photo‐electric‐biological
technology,
is
shown
considerable
potential
for
high‐performance
detection
in
biological
sensing.
High
gating
effect
and
current
always
pursuit
to
improve
the
performances
of
OPECT,
but
date,
their
inherent
channel
materials
invariant
structure
limit
further
development.
The
challenge
addressed
through
new
bipolar‐driven
OPECT
signal
amplification
efficient
modulation.
Herein,
inspired
by
self‐powered
(PEC)
systems,
enhancement‐mode
poly(3,4‐ethylenedioxythiophene):poly(styrene
sulfonate)
(PEDOT:PSS)
powered
Z‐scheme
COF/Cu
2
O@Cu
PtNCs
photocathode
CdIn
S
4
photoanode
proposed.
It
exhibits
an
enhanced
remarkable
gain
≈7613,
which
much
higher
than
single‐photoelectrode
ones
will
have
beneficial
impact
on
achieving
sensitive,
portable,
reliable
sensing
devices.
Moreover,
sandwich
system
composed
multifunctional
COF‐based
nanomaterials
target‐mediated
biomimetic
precipitation
reaction
designed
upon
photocathode,
resulting
dual
realizing
alpha‐fetoprotein
(AFP)
with
linear
range
32
fg
mL
−1
–10
ng
low
22
.
