Borophene and Its Composite‐Based Electrochemical Sensors DOI Creative Commons

Aashutosh Dube,

Shweta J. Malode,

Maha Alruwaili

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

Borophene is found as a monolayer of boron. It emerges promising 2D nanomaterial with unique characteristics like anisotropic metallic nature and direction‐dependent mechanical optical properties. High electrical conductivity, surface corrugation, high chemical reactivity, substantially electron mobility are the properties borophene that relevant to electrochemical sensor applications. This study encapsulates advancements in borophene‐based sensors biosensors for sensing analytes, including glucose, urea, dopamine, arsenic toxicity water. A succinct summary has been presented, all significant attributes, determined limit detection, established linear dynamic range, utilized analytical approach, documented stability. The stability concerns have mitigated by passivation encapsulation, whereas real‐time applications can be advanced collaborating industries, developing devices, conducting pilot tests. article delineates process's constraints problems while proposing alternative techniques remedies.

Language: Английский

Nanoparticle Strategies for Treating CNS Disorders: A Comprehensive Review of Drug Delivery and Theranostic Applications DOI Open Access
Corneliu Toader, Adrian Dumitru,

Lucian Eva

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(24), P. 13302 - 13302

Published: Dec. 11, 2024

This review aims to address the significant challenges of treating central nervous system (CNS) disorders such as neurodegenerative diseases, strokes, spinal cord injuries, and brain tumors. These are difficult manage due complexity disease mechanisms protective blood–brain barrier (BBB), which restricts drug delivery. Recent advancements in nanoparticle (NP) technologies offer promising solutions, with potential applications delivery, neuroprotection, neuroregeneration. By examining current research, we explore how NPs can cross BBB, deliver medications directly targeted CNS regions, enhance both diagnostics treatment. Key NP strategies, passive targeting, receptor-mediated transport, stimuli-responsive systems, demonstrate encouraging results. Studies show that may improve minimize side effects, increase therapeutic effectiveness models Alzheimer’s, Parkinson’s, stroke, glioblastoma. thus represent a approach for disorder management, combining delivery diagnostic capabilities enable more precise effective treatments could significantly benefit patient outcomes.

Language: Английский

Citations

4
Selective and Sensitive OECT Sensors with Doped MIP-Modified GCE/MWCNT Gate Electrodes for Real-Time Detection of Serotonin DOI Creative Commons

Amin Mehrehjedy,

John K. Eaton, Kan Tang

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 24, 2025

Organic electrochemical transistors (OECTs) represent a promising platform for biosensing applications in aqueous environments, including the sensitive detection of neurotransmitter molecules, such as serotonin (SE). Conventional methods SE detection, HPLC and ELISA, are time-consuming expensive. Electrochemical sensors, while cost-effective, often struggle with real-time selectivity issues due to interference from similar biomolecules, dopamine (DA), ascorbic acid (AA), uric (UA). These interferents particularly challenging OECT because they easier oxidize than on gate electrode. Molecularly imprinted polymer (MIP) has gained increasing interest analysis, providing cost-effective method selective various analytes by creating matching cavities film. Herein, glassy carbon/multiwall carbon nanotube (GCE/MWCNT) electrode was modified PSS–doped overoxidized molecularly (DOMIP) layer an sensor. Characterizations cyclic voltammograms (CV), impedance spectroscopy (EIS), scanning electron microscopy (SEM), Raman spectroscopy, wide-angle X-ray scattering (WAXS) demonstrate improved conductivity DOMIP modification. The resulting GCE/MWCNT/DOMIP sensor demonstrated low limit 0.31 μM measurements, comparable that GCE/MWCNT However, showed little toward SE. In addition SE-templated cavities, modification leveraged electrostatic interactions between negatively charged PSS– dopant positively molecules achieve higher sensitivity compared other or neutral concentration range - 3.1 μM. findings suggest combined electrode, doping strategy used DOMIP-modified sensors could provide low-cost way monitoring complex biological samples without usage noble-metal expensive antibodies, which is potentially suitable large-scale medical diagnosis.

Language: Английский

Citations

0
Electrochemical Sensors for Enhanced and Rapid Detection of Illicit Drugs DOI
Sumera Khizar,

Nadia Zine,

Monique Sigaud

et al.

Electroanalysis, Journal Year: 2025, Volume and Issue: 37(3)

Published: March 1, 2025

The consumption of illicit drugs is spread worldwide and remains a challenge for concerned authorities. Hence, it vital to develop effective precise methods detecting these types compounds in biological fluids, seized street samples, wastewaters. Electrochemical sensors are extensively used analysis many fields represent an exclusive prospect permit inexpensive, fast, accurate monitoring detection simultaneously. approaches mainly open forensic investigation because their high performance turbid complex matrices. In this minireview, recent electrochemical strategies applied the different samples have been presented.

Language: Английский

Citations

0
Electrochemical surface modification and regeneration of carbon fiber microelectrodes in deionized water DOI Creative Commons
Tao Fang, Tingting Wang, Yuan Li

et al.

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION), Journal Year: 2025, Volume and Issue: unknown, P. 100531 - 100531

Published: March 1, 2025

Language: Английский

Citations

0
Surface Engineering Magnetic Nanoparticles with Redox and Biological Properties DOI
Jing Liu,

Ye Chen,

Feixiong Chen

et al.

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Magnetic nanoparticles (MNPs) are recognized as valuable tools for derived electrochemical biosensors and offer immense potential the efficient diagnosis detection of disease biomarkers. Herein, a new step-by-step approach development multifunctional MNPs that exhibit both redox biological properties is described. First, chemical cross-linking was employed to label these with dyes (ferrocene, anthraquinone, or methylene blue). Bovine serum albumin (BSA) then applied terminal protective layer. Next, click chemistry engineer immunoglobulin G (IgG) onto surface (IgG number 35 ± 8 per MNP), providing multifunctionality. Before after engineering, exhibited high-quality size distributions, characterized by differential centrifugal sedimentation (DCS). Square-wave voltammetry used reveal presence 21.8 1.3 ferrocene molecules on each anti-CD63-based MNP, anti-CD63 antibodies still maintained their bioactivity toward CD63 antigen. These could be promising advancing MNP-assisted meeting needs single-nanoparticle electrochemistry.

Language: Английский

Citations

0
Self-assembled AuNPs on Niobium Carbide (Nb2C) MXene-based Apta-sensor for Progesterone Recognition in Female Sweat and Serum Sample DOI
Sachin Ganpat Chavan,

Pooja Ramrao Rathod,

Aneesh Koyappayil

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137722 - 137722

Published: April 1, 2025

Language: Английский

Citations

0
An in situ-boosted electrochemiluminescence biosensor for serotonin detection sensitized with Co3O4 nanoplates and self-feedback DNA recycling DOI
Yong‐Guang Gao, Qiumei Feng, Xiangmin Miao

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117464 - 117464

Published: April 1, 2025

Language: Английский

Citations

0
Borophene and Its Composite‐Based Electrochemical Sensors DOI Creative Commons

Aashutosh Dube,

Shweta J. Malode,

Maha Alruwaili

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

Borophene is found as a monolayer of boron. It emerges promising 2D nanomaterial with unique characteristics like anisotropic metallic nature and direction‐dependent mechanical optical properties. High electrical conductivity, surface corrugation, high chemical reactivity, substantially electron mobility are the properties borophene that relevant to electrochemical sensor applications. This study encapsulates advancements in borophene‐based sensors biosensors for sensing analytes, including glucose, urea, dopamine, arsenic toxicity water. A succinct summary has been presented, all significant attributes, determined limit detection, established linear dynamic range, utilized analytical approach, documented stability. The stability concerns have mitigated by passivation encapsulation, whereas real‐time applications can be advanced collaborating industries, developing devices, conducting pilot tests. article delineates process's constraints problems while proposing alternative techniques remedies.

Language: Английский

Citations

0