Comparative Assessment of Post‐Fatigue Resistance of Mandibular First Molars Restored With Polyether Ether Ketone and Lithium Disilicate Endocrowns DOI Creative Commons
Mehrak Amjadi,

Mohammad Raouf Safari,

Ramin Dini Torkamani

et al.

The Scientific World JOURNAL, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Background and Objectives: Contemporary dentistry focuses on more conservative treatment options such as endocrown restorations application of dental materials with higher resemblance to tooth structure. Polyether ether ketone (PEEK) polymer is a material used for the fabrication endocrowns. This study aimed compare post‐fatigue resistance (PFR) mandibular first molars restored PEEK lithium disilicate (LS 2 ) restorations. Materials Methods: in vitro, experimental was conducted 20 human similar dimensions. The teeth were prepared restoration assigned two groups ( n = 10) LS After by computer‐aided design manufacturing (CAD‐CAM) technique, cemented resin cement. Next, underwent 15,000 thermal cycles followed cyclic loading 600,000 compressive force (100 N, 4 Hz) then subjected load universal testing machine. causing failure recorded PFR respective restoration. mode also inspected under light microscope. Data analyzed independent t ‐test chi‐square, Mann–Whitney, Fisher’s exact tests α < 0.05). Results: endocrowns showed significantly than those Irreparable fractures dominant both groups. Conclusion: may serve suitable alternative

Language: Английский

3D Cryo‐Printed Hierarchical Porous Scaffolds Harmonized with Hybrid Nanozymes for Combinatorial Mitochondrial Therapy: Enhanced Diabetic Bone Regeneration via Micromilieu Remodeling DOI
Qingsong Deng, Xuran Li,

Po‐Lin Liu

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: April 13, 2024

Abstract Regeneration of bone defects in diabetic patients has always been a significant challenge clinical treatment. The pathologic micromilieu, characterized by mitochondrial dysfunction, excessive reactive oxygen species (ROS) accumulation, cellular senescence, and chronic inflammation, compromises innate healing capacity. 3D cryo‐printing technology is utilized tissue engineering to fabricate hierarchical porous scaffolds that promote conducive microenvironment for adhesion, migration, proliferation, nutrient exchange. Nanozymes are used as synthetic mimics natural enzymes scavenge ROS, addressing the limitations antioxidative enzymes. To remodel regeneration cryo‐printed polyaryletherketone with carboxyl groups (PAEK‐COOH) 45S5 bioactive glass (BG) scaffold (PBG scaffold), harmonized hybrid nanozymes comprising SS31‐enhanced manganese dioxide (MnO 2 )‐ferritin biomimetic nanozyme (MF@S nanozyme), developed combinatorial therapy. MF@S specifically targets mitochondria enhance function, ROS accumulated mitochondria, suppress (mtROS) production, thus rejuvenate aging cells, regulate macrophage polarization, modulate differentiation osteoblasts osteoclasts. This PBG‐MF@S combines therapy system micromilieu presents promising therapeutic approach diabetes.

Language: Английский

Citations

7

The impact of hyaluronic acid coating on polyether ether ketone dental implant surface: An in vitro analysis DOI Creative Commons

Mohammed Aso Abdulghafor,

Zanyar Amin

The Saudi Dental Journal, Journal Year: 2024, Volume and Issue: 36(10), P. 1326 - 1332

Published: July 17, 2024

Polyether ether ketone (PEEK), a biocompatible polymer, is being explored as an alternative to metallic alloys for dental implants due its aesthetic and mechanical properties. This study aimed enhance the surface biofunctionality through evaluating human MG-63 osteoblastic cell survival, proliferation, differentiation, mineralization.

Language: Английский

Citations

3

Evaluation of Shear Bond Strength and Failure Modes of Lithium Disilicate Ceramic Veneering Material to Different High-Performance Polymers DOI Open Access
Sarah M. Alnafaiy, Nawaf Labban, Refal Albaijan

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(5), P. 554 - 554

Published: Feb. 20, 2025

This study assessed the shear bond strength (SBS) and failure modes of lithium disilicate ceramic veneering material to different high-performance polymers. Thirty-six square specimens measuring 7 × 2 ± 0.05 mm were prepared from pure polyetheretherketone (PEEK), Bio-high performance PEEK (BioHPP) Trilor discs. Polymer air-borne abraded utilizing aluminum oxide particles, cleaned, a bonding agent was applied (visio. link). The LDC (3 mm) milled, hydrofluoric acid etched (9.5%) primed (Clearfil ceramic). bonded polymer using dual-cured resin cement (Panavia V5) light polymerized. subjected 5000 cycles physiological aging by thermocycling, SBS test performed in universal testing machine at 0.5 mm/min cross-head speed. debonded analyzed determine primary sites (adhesive, mixed or cohesive). Data analysis one-way ANOVA post hoc Tukey (α ≤ 0.05). BioHPP demonstrated highest values (23.94 1.43 MPa), group recorded lowest (17.09 1.07 MPa). showed mean 21.21 1.51 MPa. comparison significant variations across all groups (p < 0.001). Regarding modes, adhesive observed 40% 90% specimens. cohesive occurred 50% 30% specimens, while no failure. Mixed failures reported 10% high followed Trilor. between tested materials statistically significant. However, implant framework above limit stipulated ISO 10477 standard (5 MPa) clinically acceptable range 10-12

Language: Английский

Citations

0

Plasma Immersion Ion Implantation Increases Adhesive Bond Strength of PEK and PEEK to Dental Composites and Enables Hydrolysis Resistance DOI Creative Commons
Will Lewin, Hedi Verena Kruse, Eva Tomaskovic‐Crook

et al.

Macromolecular Materials and Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Abstract The additive manufacturing technology known as selective‐laser‐sintering is available for the poly‐aryl‐ether‐ketone (PAEK) family of high‐strength polymers, enabling rapid production personalized dental and mandibular reconstructions at or near point‐of‐care. PAEK segmental replacements, bridges, abutments are transitioning to clinical use. There remains a need improved adhesion between polymers adhesives including composite resin cements. Without surface modification, there weak bond especially when polymer smooth. Plasma‐immersion‐ion‐implantation (PIII) applied demonstrate significant increase in strength Polyether–ether–ketone (PEEK) Poly–ether–ketone (PEK) commonly used cement, multiple levels interface roughness. A validated predictive model function roughness expressed area ratio presented that demonstrates relative effect PIII mechanical interlocking. results show achieved using retained even primer step omitted, an important advance has been associated with hydrolysis‐induced weakening. long‐term water immersion test shows PIII‐assisted primer‐free retains its while all primer‐assisted bonds weakened.

Language: Английский

Citations

0

Low‐Temperature Deposited Amorphous Poly(aryl ether ketone) Hierarchically Porous Scaffolds with Strontium‐Doped Mineralized Coating for Bone Defect Repair DOI
Tianze Sun,

Huagui Huang,

Yantao Zhao

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: May 8, 2024

In recent years, the demand for clinical bone grafting has increased. As a new solution orthopedic implants, polyether ether ketone (PEEK, crystalline PAEK) excellent comprehensive performance and is practically applied in clinic. this research, noteworthy elevated scheme to enhance of PEEK scaffolds presented. The amorphous aggregated poly (aryl ketone) (PAEK) resin prepared as matrix material, which maintains high mechanical strength can be processed through solution. So, tissue engineering with multilevel pores printed by low-temperature deposited manufacturing (LDM) improve biologically inert smooth surfaces. Also, feature PAEK's processing profitable uniformly add functional components repair. Ultimately, A system implantable PAEK material based on intermolecular interactions, surface topology, modification established. specific steps include synthesizing that contain polar carboxyl structures, preparing bioinks fabricating LDM, preparation strontium-doped mineralized coatings, evaluation their osteogenic properties vitro vivo, investigation effect mechanism promoting differentiation. This work provides an upgraded materials application.

Language: Английский

Citations

2

DFT-based investigation of polyetherketoneketone materials for surface modification for dental implants DOI Creative Commons

Ravinder S Saini,

Rayan Ibrahim H Binduhayyim, Mohamed Saheer Kuruniyan

et al.

European journal of medical research, Journal Year: 2024, Volume and Issue: 29(1)

Published: Aug. 29, 2024

Polyetherketoneketone (PEKK) is a high-performance thermoplastic polymer with unique structural and mechanical properties that make it promising candidate for surface modification of dental implants. This study was conducted to investigate the feasibility PEKK this purpose using Cambridge Serial Total Energy Package (CASTEP) code based on density functional theory (DFT).

Language: Английский

Citations

2

The Artificial Disc Nucleus and Other Strategies for Replacement of the Nucleus Pulposus: Past, Present and Future Designs for an Emerging Surgical Solution DOI Creative Commons

Greg Sacks,

Vincent DeStefano,

Claire Parker

et al.

Engineered Regeneration, Journal Year: 2024, Volume and Issue: 5(2), P. 269 - 281

Published: May 8, 2024

Nucleus Pulposus (NP) Replacement is a developing surgical methodology for the treatment of pathology related to degeneration intervertebral discs (IVDs). This article provides necessary context regarding pathologies treated with this technology, biomechanical structure and function IVD, procedures technology aims replace. Primarily, it an overview discussion commercial experimental preformed in situ curing prosthesis designs reported scientific literature summarizes results clinical studies evaluating their efficacy. Contextual updated information on most recent research into NP replacement novel hydrogel tissue engineering (TE) strategies described. allows potential improvement degenerative spinal through minimally invasive techniques.

Language: Английский

Citations

0

Electrospinning of Polyetherketoneketone Fibers: The Effect of Fabrication Regime on the Morphology, Physico-Chemical and Biological Characteristics DOI
Semen Goreninskii, Evgeny Melnik, Evgenii Plotnikov

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0

Electrospinning of Polyetherketoneketone Fibers: The Effect of Fabrication Regime on the Morphology, Physico-Chemical and Biological Characteristics DOI
Semen Goreninskii, Evgeny Melnik, Evgenii Plotnikov

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0

Electrospinning of polyetherketoneketone fibers: the effect of fabrication regime on the morphology, physico-chemical and biological characteristics DOI
Semen Goreninskii, Evgeny Melnik, Evgenii Plotnikov

et al.

Polymer, Journal Year: 2024, Volume and Issue: 311, P. 127549 - 127549

Published: Aug. 26, 2024

Language: Английский

Citations

0