Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Nov. 13, 2024
Optical
patterning
of
colloidal
particles
is
a
scalable
and
cost-effective
approach
for
creating
multiscale
functional
structures.
Existing
methods
often
use
high-intensity
light
sources
customized
optical
setups,
making
them
less
feasible
large-scale
microfabrication
processes.
Here,
we
report
an
method
semiconductor
nanoparticles
by
light-triggered
modulation
their
surface
charge.
Rather
than
using
as
the
primary
energy
source,
this
utilizes
UV-induced
cleavage
ligands
to
modify
charges,
thereby
facilitating
self-assembly
on
charged
substrate
via
electrostatic
interactions.
By
citrate-treated
ZnO
nanoparticles,
uniform
patterns
with
variable
thicknesses
can
be
achieved.
These
multilayered
are
fabricated
into
UV
detector
on/off
ratio
exceeding
10
Molecular Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
20(1), P. 767 - 774
Published: Nov. 2, 2022
Natural
polymer-based
hydrogels
are
excellent
for
encapsulating
hydrophilic
drugs,
but
they
mechanically
weak
and
degrade
easily.
In
this
communication,
we
exploit
the
electrostatic
interaction
between
nanosilicates
(nSi)
gelatin
methacrylate
(GelMA)
to
form
a
tough
nanocomposite
hydrogel
pharmaceutical
drug
delivery.
These
hydrogels,
prepared
at
subzero
temperatures
cryogels,
displayed
macroporous
structures,
which
favors
cell
infiltration.
The
designed
cryogel
also
showed
slower
rate
of
degradation.
Furthermore,
encapsulated
small
molecule
metformin
sustained
release
under
physiological
conditions.
Cryogel-loaded
reduced
effect
endothelial
injury
caused
by
nutrient
deprivation
in
vitro.
Finally,
hypothesize
that
versatile
material
will
find
use
diverse
biomedical
applications.
Biofabrication,
Journal Year:
2024,
Volume and Issue:
16(4), P. 045023 - 045023
Published: July 12, 2024
Abstract
Recent
3D-printing
research
showed
the
potential
of
using
plant-protein-enriched
inks
to
fabricate
cultivated
meat
(CM)
via
agar-based
support
baths.
However,
for
fabricating
large,
customized,
structured,
thick
cellular
constructs
and
further
cultivation,
improved
capabilities
diffusion
limit
circumvention
are
warranted.
The
presented
study
harnesses
advanced
printing
tissue
engineering
concepts
such
purpose.
By
improving
bath
composition
altering
design
execution,
large-scale,
marbled,
0.5-cm-thick
rib-eye
shaped
were
obtained.
featured
stable
fibrous
architectures
comparable
those
structured-meat
products.
Customized
multi-cellular
with
distinct
regions
produced
as
well.
Furthermore,
sustainable
1-cm-thick
carefully
designed
produced,
which
successfully
maintained
cell
viability
activity
3
weeks,
through
combined
effects
void-incorporation
dynamic
culturing.
As
geometrically
complex
construct
fabrication
suitable
long-term
cultivation
was
demonstrated,
these
findings
hold
great
promise
advancing
structured
CM
research.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Nov. 13, 2024
Optical
patterning
of
colloidal
particles
is
a
scalable
and
cost-effective
approach
for
creating
multiscale
functional
structures.
Existing
methods
often
use
high-intensity
light
sources
customized
optical
setups,
making
them
less
feasible
large-scale
microfabrication
processes.
Here,
we
report
an
method
semiconductor
nanoparticles
by
light-triggered
modulation
their
surface
charge.
Rather
than
using
as
the
primary
energy
source,
this
utilizes
UV-induced
cleavage
ligands
to
modify
charges,
thereby
facilitating
self-assembly
on
charged
substrate
via
electrostatic
interactions.
By
citrate-treated
ZnO
nanoparticles,
uniform
patterns
with
variable
thicknesses
can
be
achieved.
These
multilayered
are
fabricated
into
UV
detector
on/off
ratio
exceeding
10
