Improvement of olfactory function in AD mice mediated by immune responses under 40 Hz light flickering

Neuroscience Letters, Journal Year: 2024, Volume and Issue: 842, P. 137958 - 137958

Published: Aug. 30, 2024

Language: Английский

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Gamma (60 Hz) auditory stimulation improves intrusions but not recall and working memory in healthy adults

Behavioural Brain Research, Journal Year: 2023, Volume and Issue: 456, P. 114703 - 114703

Published: Oct. 7, 2023

Language: Английский

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Therapeutic potential of gamma entrainment using sensory stimulation for cognitive symptoms associated with schizophrenia

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 161, P. 105681 - 105681

Published: April 17, 2024

Schizophrenia is a complex neuropsychiatric disorder with significant morbidity. Treatment options that address the spectrum of symptoms are limited, highlighting need for innovative therapeutic approaches. Gamma Entrainment Using Sensory Stimulation (GENUS) an emerging treatment disorders uses sensory stimulation to entrain impaired oscillatory network activity and restore brain function. Aberrant often underlies experienced by patients schizophrenia. We propose GENUS has potential This paper reviews current status schizophrenia explores use as adjunctive treatment, specifically through gamma entrainment. Impaired frequency entrainment observed in patients, particularly response auditory visual stimuli. Thus, stimulation, such music listening, may have individuals holds novel improve lives schizophrenia, but further research required determine efficacy GENUS, optimize its delivery window, develop strategies implementation specific patient populations.

Language: Английский

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Optimal gamma‐band entrainment of visual cortex

Human Brain Mapping, Journal Year: 2024, Volume and Issue: 45(10)

Published: July 5, 2024

Abstract Visual entrainment is a powerful and widely used research tool to study visual information processing in the brain. While many studies have focused on frequencies around 14–16 Hz, there renewed interest understanding at higher (e.g., gamma‐band entrainment). Notably, recent groundbreaking demonstrated that 40 Hz may therapeutic effects context of Alzheimer's disease (AD) by stimulating specific neural ensembles, which utilize GABAergic signaling. Despite such promising findings, few investigated optimal parameters for entrainment. Herein, we examined whether stimulation 32, 40, or 48 produces responses using high‐density magnetoencephalography (MEG). Our results indicated strong localizing primary cortex each condition. Entrainment were stronger 32 relative indicating more robust synchronization ensembles these lower frequencies. In addition, showed typical patterns habituation across trials, but this effect was absent Hz. Finally, connectivity between parietal prefrontal cortices tended be strongest These suggest resonate thus entrain readily photic Emerging AD therapies, date, effective gamma frequencies, although additional work clinical populations needed confirm findings. Practitioner Points Gamma‐band has emerged as approach eliminating amyloid disease, its are unknown. We found compared suggesting prefer relatively findings inform development refinement innovative therapies cortical functions.

Language: Английский

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Temporal gamma tACS and auditory stimulation affect verbal memory in healthy adults

Psychophysiology, Journal Year: 2024, Volume and Issue: 61(11)

Published: July 16, 2024

Research suggests a potential of gamma oscillation entrainment for enhancing memory in Alzheimer's disease and healthy subjects. Gamma can be accomplished with oscillatory electrical, but also sensory stimulation. However, comparative studies between stimulation transcranial alternating current (tACS) effects on processes are lacking. This study examined the rhythmic auditory (rAS) temporal gamma-tACS verbal long-term (LTM) working (WM) 74 individuals. Participants were assigned to two groups according techniques (rAS or tACS). Memory was assessed three experimental blocks, which each participant administered control, 40, 60 Hz counterbalanced order. All interventions well-tolerated, participants reported mostly comparable side real (40 Hz) control condition. LTM immediate delayed recall remained unaffected by stimulations, while intrusions decreased during Notably, 40 improved WM compared stimulations. These results highlight cortex reducing improving performance, respectively, probably due specific oscillations cortex. The shed light these neuromodulation tools functions, their applications cognitive enhancement clinical trials.

Language: Английский

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Immersive gamma music as a tool for enhancing glymphatic clearance in astronauts while improving their mental well-being

Life Sciences in Space Research, Journal Year: 2024, Volume and Issue: 44, P. 86 - 89

Published: Oct. 30, 2024

Language: Английский

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