An open-label pilot trial of a five-day, accelerated rTMS protocol in bipolar II depression DOI
Giacomo d’Andrea, Luisa De Risio, Giorgio Di Lorenzo

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Predictors of response to accelerated rTMS in the treatment of treatment-resistant depression DOI
Qi Wang,

Li Li,

Hongyan Zhao

et al.

European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Language: Английский

Citations

1
Effect of Acute Ketamine Treatment on Sympathetic Regulation Indexed by Electrodermal Activity in Adolescent Major Depression DOI Creative Commons
Veronika Kováčová,

Andrea Macejova,

Ingrid Tonhajzerová

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(3), P. 358 - 358

Published: March 10, 2024

Ketamine is a potential rapid-onset antidepressant characterized by sympathomimetic effects. However, the question of ketamine’s use in treating adolescents’ major depressive disorder (MDD) still discussed. Thus, we aimed to study acute effect ketamine infusion treatment on sympathetic regulation using electrodermal activity (EDA) addition an assessment symptomatology MDD adolescents. Twenty hospitalized adolescent girls with (average age: 15.0 ± 1.46 yrs.) were examined before and two hours after single intravenous ketamine. EDA was continuously recorded for 6 min, symptoms assessed administration. The evaluated parameters included skin conductance level (SCL), nonspecific responses (NS-SCRs), MADRS (questions no. 1–10, total score), CDI (items A–E, score). showed no significant changes treatment, significantly reduced infusion. analysis revealed negative correlation between index SCL CDI-A, CDI-E, score NS-SCRs 4 treatment. In conclusion, improved without EDA, indicating its safety efficiency as intervention MDD.

Language: Английский

Citations

0
Maintenance Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder DOI
Salman Akram,

Imaan Nanji,

Ismail Deniz

et al.

Journal of Ect, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 26, 2024

Abstract Repetitive transcranial magnetic stimulation (rTMS) is an effective therapy for acute treatment of major depressive disorder (MDD). However, the efficacy and optimal strategy delivering maintenance rTMS beyond remains unclear. This meta-analysis aims to quantify effect in MDD compares difference between fixed rescue protocols. We conducted a 14 studies (N = 705) comparing depression rating scores before after rTMS. Standardized mean adjusted sample size (Hedges g ) were used as size. Subgroup analysis was performed compare treatment. Maintenance associated with statistically significant improvement (standardized [SMD] 0.75; confidence interval [CI] −1.25 −0.25). The random effects model had Q value 142.67 ( P < 0.0001) I 2 90%, supporting heterogeneity among studies. prediction yielded possible from −2.54 1.05. subgroup showed stronger protocol (SMD −1.17; CI −2.13 −0.21) compared −0.45; −1.00.16). Although not (Q-between 2.56, df-between 1, 0.1096), large observed subgroups. appears be maintaining remission preventing relapse MDD. Significant warrants caution interpreting results. These findings suggest need standard protocols consensus guidelines delivery

Language: Английский

Citations

0
An open-label pilot trial of a five-day, accelerated rTMS protocol in bipolar II depression DOI
Giacomo d’Andrea, Luisa De Risio, Giorgio Di Lorenzo

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

0