Chitosan-based materials: Preparation, modification and application

Journal of Cleaner Production, Journal Year: 2022, Volume and Issue: 355, P. 131825 - 131825

Published: April 20, 2022

Language: Английский

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A review of current advancements for wound healing: Biomaterial applications and medical devices

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2022, Volume and Issue: 110(11), P. 2542 - 2573

Published: May 17, 2022

Wound healing is a complex process that critical in restoring the skin's barrier function. This can be interrupted by numerous diseases resulting chronic wounds represent major medical burden. Such fail to follow stages of and are often complicated pro-inflammatory milieu attributed increased proteinases, hypoxia, bacterial accumulation. The comprehensive treatment still regarded as significant unmet need due symptoms caused metabolic disorder wound microenvironment. As result, several advanced devices, such dressings, wearable monitors, negative pressure therapy surgical sutures, have been developed correct environment achieve skin tissue regeneration. Most devices encompass wide range products containing natural (e.g., chitosan, keratin, casein, collagen, hyaluronic acid, alginate, silk fibroin) synthetic polyvinyl alcohol, polyethylene glycol, poly[lactic-co-glycolic acid], polycaprolactone, polylactic acid) polymers, well bioactive molecules chemical drugs, silver, growth factors, stem cells, plant compounds). review addresses these with focus on biomaterials applications, aiming deliver theoretical reference for further research healing.

Language: Английский

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Sustainable Agriculture Systems in Vegetable Production Using Chitin and Chitosan as Plant Biostimulants

Biomolecules, Journal Year: 2021, Volume and Issue: 11(6), P. 819 - 819

Published: May 31, 2021

Chitin and chitosan are natural compounds that biodegradable nontoxic have gained noticeable attention due to their effective contribution increased yield agro-environmental sustainability. Several effects been reported for application in plants. Particularly, it can be used plant defense systems against biological environmental stress conditions as a growth promoter—it increase stomatal conductance reduce transpiration or applied coating material seeds. Moreover, promoting chitinolytic microorganisms prolonging storage life through post-harvest treatments, benefit nutrient delivery plants since may prevent leaching improve slow release of nutrients fertilizers. Finally, remediate polluted soils the removal cationic anionic heavy metals improvement soil properties. On other hand, chitin also has many beneficial such promotion, improved nutrition ability modulate plants’ resistance abiotic biotic stressors. The present review presents literature overview regarding chitin, derivatives on horticultural crops, highlighting important role modern sustainable crop production; main limitations well future prospects applications this particular biostimulant category presented.

Language: Английский

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Recent Advances in Chitosan-Based Applications—A Review

Materials, Journal Year: 2023, Volume and Issue: 16(5), P. 2073 - 2073

Published: March 3, 2023

Chitosan derived from chitin has gathered much interest as a biopolymer due to its known and possible broad applications. Chitin is nitrogen-enriched polymer abundantly present in the exoskeletons of arthropods, cell walls fungi, green algae, microorganisms, radulae beaks molluscs cephalopods, etc. promising candidate for wide variety applications macromolecular structure unique biological physiological properties, including solubility, biocompatibility, biodegradability, reactivity. derivatives have been be applicable medicine, pharmaceuticals, food, cosmetics, agriculture, textile paper industries, energy industry, industrial sustainability. More specifically, their use drug delivery, dentistry, ophthalmology, wound dressing, encapsulation, bioimaging, tissue engineering, food packaging, gelling coating, additives preservatives, active biopolymeric nanofilms, nutraceuticals, skin hair care, preventing abiotic stress flora, increasing water availability plants, controlled release fertilizers, dye-sensitised solar cells, wastewater sludge treatment, metal extraction. The merits demerits associated with chitosan above are elucidated, finally, key challenges future perspectives discussed detail.

Language: Английский

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Printability and Cell Viability in Extrusion-Based Bioprinting from Experimental, Computational, and Machine Learning Views

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(2), P. 40 - 40

Published: April 10, 2022

Extrusion bioprinting is an emerging technology to apply biomaterials precisely with living cells (referred as bioink) layer by create three-dimensional (3D) functional constructs for tissue engineering. Printability and cell viability are two critical issues in the extrusion process; printability refers capacity form maintain reproducible 3D structure characterizes amount or percentage of survival during printing. Research reveals that both can be affected various parameters associated construct design, bioinks, process. This paper briefly reviews literature aim identify affecting highlight methods strategies rigorously determining optimizing them improved viability. presents review discussion mainly from experimental, computational, machine learning (ML) views, given their promising this field. It envisioned ML will a powerful tool advance

Language: Английский

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3D printing to innovate biopolymer materials for demanding applications: A review

Materials Today Chemistry, Journal Year: 2021, Volume and Issue: 20, P. 100459 - 100459

Published: April 22, 2021

Language: Английский

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Recent progressions in biomedical and pharmaceutical applications of chitosan nanoparticles: A comprehensive review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 231, P. 123354 - 123354

Published: Jan. 18, 2023

Language: Английский

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Chitosan-Based Biomaterials for Bone Tissue Engineering Applications: A Short Review

Polymers, Journal Year: 2022, Volume and Issue: 14(16), P. 3430 - 3430

Published: Aug. 22, 2022

Natural bone tissue is composed of calcium-deficient carbonated hydroxyapatite as the inorganic phase and collagen type I main organic phase. The biomimetic approach scaffold development for engineering application focused on mimicking complex characteristics. Calcium phosphates are used in numerous studies bioactive phases to mimic natural mineral. In order phase, synthetic (e.g., poly(ε-caprolactone), polylactic acid, poly(lactide-co-glycolide acid)) alginate, chitosan, collagen, gelatin, silk) biodegradable polymers used. However, materials obtained from sources accepted better by human organism, have attracted increasing attention. Over last three decades, chitosan was extensively studied a polymer suitable applications. Different types chitosan-based biomaterials molded macroporous, fiber-based, hydrogel, microspheres 3D-printed) with specific properties different regenerative applications were developed due chitosan's unique properties. This review summarizes state-of-the-art regeneration relevant composites.

Language: Английский

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Chitosan-based nanostructured biomaterials: Synthesis, properties, and biomedical applications

Advanced Industrial and Engineering Polymer Research, Journal Year: 2023, Volume and Issue: 7(1), P. 79 - 99

Published: July 19, 2023

Chitosan is obtained from chitin, which abundantly found in crustaceans and through various methods. The demineralization, deproteinization, discoloration, deacetylation of chitin produce chitosan consisting D-glucosamine N-acetyl units that are linked β-(1,4)-glycosidic linkages. has gained significant attention the biomedical field due to its unique properties such as abundance, renewability, non-toxic nature, antimicrobial activity, biodegradability, polyfunctionality. One key why it been heavily utilized field. To provide a comprehensive overview chitosan, this review discusses extraction based on source It also delves into chemical modifications nanocomposite development using natural synthetic materials. emphasizes multitude make an excellent choice for wide range applications. mechanisms antibacterial activity factors affecting activity. Additionally, highlights hemocompatibility, antioxidant anti-inflammation, other contribute suitability different applications, including wound dressing materials, drug delivery carriers, biosensing diagnostic devices, bone substitutes, bioimaging. While discussing some limitations concludes with future perspective developing multifunctional chitosan-based nanomaterials could potentially move laboratory clinical trials treating diseases.

Language: Английский

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A review on four-dimensional (4D) bioprinting in pursuit of advanced tissue engineering applications

Bioprinting, Journal Year: 2022, Volume and Issue: 27, P. e00203 - e00203

Published: March 30, 2022

Language: Английский

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