Bacterial biofilm and extracellular polymeric substances in the treatment of environmental pollutants: Beyond the protective role in survivability

Journal of Cleaner Production, Journal Year: 2022, Volume and Issue: 379, P. 134759 - 134759

Published: Oct. 19, 2022

Language: Английский

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A Review of Biofilm Formation of Staphylococcus aureus and Its Regulation Mechanism

Antibiotics, Journal Year: 2022, Volume and Issue: 12(1), P. 12 - 12

Published: Dec. 22, 2022

Bacteria can form biofilms in natural and clinical environments on both biotic abiotic surfaces. The bacterial aggregates embedded are formed by their own produced extracellular matrix. Staphylococcus aureus (S. aureus) is one of the most common pathogens biofilm infections. formation protect bacteria from being attacked host immune system antibiotics thus be persistent against external challenges. Therefore, treatments for infections currently encountering difficulty. To address this critical challenge, a new effective treatment method needs to developed. A comprehensive understanding regulation mechanisms may provide meaningful insights antibiotic resistance due biofilms. In review, we discuss an overview S. including process, structural functional properties matrix, mechanism regulating formation.

Language: Английский

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Bacterial extracellular polymeric substances: Biosynthesis and interaction with environmental pollutants

Chemosphere, Journal Year: 2023, Volume and Issue: 332, P. 138876 - 138876

Published: May 8, 2023

Language: Английский

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Potential and prospects of Actinobacteria in the bioremediation of environmental pollutants: Cellular mechanisms and genetic regulations

Microbiological Research, Journal Year: 2023, Volume and Issue: 273, P. 127399 - 127399

Published: May 3, 2023

Language: Английский

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The variation on structure and immunomodulatory activity of polysaccharide during the longan pulp fermentation

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 222, P. 599 - 609

Published: Sept. 26, 2022

Language: Английский

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Biofilm control strategies in the light of biofilm-forming microorganisms

World Journal of Microbiology and Biotechnology, Journal Year: 2023, Volume and Issue: 39(5)

Published: March 24, 2023

Language: Английский

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Comprehensive review on recent trends and perspectives of natural exo-polysaccharides: Pioneering nano-biotechnological tools

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 265, P. 130747 - 130747

Published: March 12, 2024

Language: Английский

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Insight into microbial synthesis of metal nanomaterials and their environmental applications: Exploration for enhanced controllable synthesis

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(11), P. 109651 - 109651

Published: Feb. 10, 2024

Language: Английский

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Biofilm Resilience: Molecular Mechanisms Driving Antibiotic Resistance in Clinical Contexts

Biology, Journal Year: 2025, Volume and Issue: 14(2), P. 165 - 165

Published: Feb. 6, 2025

Healthcare-associated infections pose a significant global health challenge, negatively impacting patient outcomes and burdening healthcare systems. A major contributing factor to healthcare-associated is the formation of biofilms, structured microbial communities encased in self-produced extracellular polymeric substance matrix. Biofilms are critical disease etiology antibiotic resistance, complicating treatment infection control efforts. Their inherent resistance mechanisms enable them withstand therapies, leading recurrent increased morbidity. This review explores development biofilms their dual roles disease. It highlights structural protective functions EPS matrix, which shields populations from immune responses antimicrobial agents. Key molecular biofilm including restricted penetration, persister cell dormancy, genetic adaptations, identified as barriers effective management. implicated various clinical contexts, chronic wounds, medical device-associated infections, oral complications, surgical site infections. prevalence hospital environments exacerbates challenges underscores urgent need for innovative preventive therapeutic strategies. evaluates cutting-edge approaches such DNase-mediated disruption, RNAIII-inhibiting peptides, DNABII proteins, bacteriophage nanoparticle-based solutions, coatings, lock therapies. also examines associated with biofilm-related diagnostic difficulties, disinfectant economic implications. emphasizes multidisciplinary approach importance understanding dynamics, role pathogenesis, advancements strategies combat biofilm-associated effectively settings. These insights aim enhance reduce burden diseases.

Language: Английский

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Anti-Bacterial Adhesion on Abiotic and Biotic Surfaces of the Exopolysaccharide from the Marine Bacillus licheniformis B3-15

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(5), P. 313 - 313

Published: May 20, 2023

The eradication of bacterial biofilm represents a crucial strategy to prevent clinical problem associated with microbial persistent infection. In this study we evaluated the ability exopolysaccharide (EPS) B3-15, produced by marine Bacillus licheniformis adhesion and formation Pseudomonas aeruginosa ATCC 27853 Staphylococcus aureus 29213 on polystyrene polyvinyl chloride surfaces. EPS was added at different times (0, 2, 4 8 h), corresponding initial, reversible irreversible attachment, after development (24 or 48 h). (300 µg/mL) impaired initial phase, preventing even when 2 h incubation, but had no effects mature biofilms. Without exerting any antibiotic activity, antibiofilm mechanisms were related modification (i) abiotic surface properties, (ii) cell-surface charges hydrophobicity, iii) cell-to-cell aggregation. addition downregulated expression genes (lecA pslA P. clfA S. aureus) involved in adhesion. Moreover, reduced (five logs-scale) (one log) human nasal epithelial cells. could represent promising tool for prevention biofilm-related infections.

Language: Английский

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