Food Science and Biotechnology, Journal Year: 2024, Volume and Issue: 34(4), P. 851 - 869
Published: Nov. 21, 2024
Language: Английский
Food Science and Biotechnology, Journal Year: 2024, Volume and Issue: 34(4), P. 851 - 869
Published: Nov. 21, 2024
Language: Английский
Small, Journal Year: 2024, Volume and Issue: 20(34)
Published: April 9, 2024
Abstract Bacterial infections and inflammation progression yield huge trouble for the management of serious skin wounds burns. However, some hydrogel dressing exhibit poor wound‐healing capabilities. Additionally, little information is given on molecular theory gelation mechanisms drug release performance from drug‐polymer network in water environment. Herein, cationic guar gum (CG) first mixed with dipotassium glycyrrhizinate (DG), then crosslinked Cu 2+ to strengthen mechanical strength followed by encapsulating mussel adhesive protein (MAP) as composite dressings. Intriguingly, CG‐Cu 0.5 ‐DG 10 possessed proper rheological properties predominantly driven strong CG‐H 2 O‐Cu ‐CG hydrogen bonding interaction. Weak DG‐CG only controlled DG initial 4 h, while main force regulating sustained within 48 h. The incorporation MAP further loosened tight crosslinking 10. screened /MAP excellent self‐healing, injectability, antibacterial, anti‐inflammatory, cell proliferation‐promotion activities high biocompatibility. Therefore, expedited wound closure S. aureus ‐infected full‐thickness model lowered necrosis unburned interspaces a rat burn model. results highlight promising translational potential ‐inspired hydrogels burns infected wounds.
Language: Английский
Citations
23Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown
Published: May 10, 2024
The persistent challenge of healing infectious wounds and the rise bacterial resistance represent significant hurdles in contemporary medicine. In this study, based on natural small molecule drug Rhein self-assembly to form hydrogels coordinate assembly with silver ions (Ag
Language: Английский
Citations
21Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: Feb. 17, 2025
Antimicrobial resistance (AMR) presents a critical global health issue, necessitating novel therapeutic strategies to manage bacterial and fungal infections. This study explores the development evaluation of multifunctional Fe3O₄@SiO₂/Schiff-base/Zn (II) magnetic nanocomposite (MNC) with enhanced antimicrobial properties. The synthesized MNC combines characteristics Fe₃O₄ nanoparticles (MNPs) properties Schiff-base ligand functionalized Zn ions. preparation involved coprecipitation Fe₃O₄, coating SiO₂ via modified Stöber method, subsequent functionalization Schiff-base/Zn complex. Comprehensive characterization using FT-IR, XRD, SEM, TEM, DLS, EDX, VSM, TGA confirmed successful synthesis, structural integrity, superparamagnetic behavior MNPs MNC. antifungal antibacterial activities were assessed against six Candida species four strains broth microdilution methods. Fe₃O₄@SiO₂/Schiff-base/Zn exhibited significant inhibitory effects, MIC values 8–64 µg/mL for 64–512 bacteria, demonstrating potent efficacy. MTT assay indicated biocompatibility across various concentrations, except slight cytotoxicity at 256 after five days. To our knowledge, this is first report integrating ligands into achieve versatile platform both biofilm inhibition applications.
Language: Английский
Citations
3Chemical Engineering Science, Journal Year: 2024, Volume and Issue: 294, P. 120104 - 120104
Published: April 6, 2024
Language: Английский
Citations
12Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: 7, P. 100425 - 100425
Published: Jan. 7, 2024
Nowadays developing wound dressing with higher antimicrobial properties which is accelerates healing, considered an emerging issue. In this study, we designed polylactic acid (PLA) films incorporated different concentrations of nanochitosan (NCH), nanocellulose (CNC), and Trachyspermum ammi (Ajwain) essential oil (AEO) in-vitro in-vivo properties, for infected healing. AEO was extracted the components were analyzed. The appearance, thickness, release AEO, evaluated used as wounds rats. mechanical selected healing results showed that thymol, P-cymene, γ-terpinene main AEO. Also, all PLA had especially gram-positive bacteria. Finally, 4% NCH 3% highest antibacterial properties. According to obtained in tensile strength test, PLA/NCH good improved films. can be a suitable option new dressings.
Language: Английский
Citations
11Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 331, P. 121874 - 121874
Published: Feb. 1, 2024
Language: Английский
Citations
11Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 336, P. 122117 - 122117
Published: April 3, 2024
Language: Английский
Citations
11International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141119 - 141119
Published: Feb. 1, 2025
Language: Английский
Citations
1Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 38, P. 102069 - 102069
Published: May 2, 2024
Language: Английский
Citations
8International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 132108 - 132108
Published: May 6, 2024
Language: Английский
Citations
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