Encapsulated essential oils in protein-polysaccharide biopolymers: characteristics and applications in the biomedical and food industries DOI
Bogale Worku, Nurelegne Tefera Shibeshi,

Tian Zhiyuan

et al.

Food Science and Biotechnology, Journal Year: 2024, Volume and Issue: 34(4), P. 851 - 869

Published: Nov. 21, 2024

Language: Английский

Copper Ion‐Inspired Dual Controllable Drug Release Hydrogels for Wound Management: Driven by Hydrogen Bonds DOI
Zhuxian Wang, Jun Liu, Yixin Zheng

et al.

Small, Journal Year: 2024, Volume and Issue: 20(34)

Published: April 9, 2024

Abstract Bacterial infections and inflammation progression yield huge trouble for the management of serious skin wounds burns. However, some hydrogel dressing exhibit poor wound‐healing capabilities. Additionally, little information is given on molecular theory gelation mechanisms drug release performance from drug‐polymer network in water environment. Herein, cationic guar gum (CG) first mixed with dipotassium glycyrrhizinate (DG), then crosslinked Cu 2+ to strengthen mechanical strength followed by encapsulating mussel adhesive protein (MAP) as composite dressings. Intriguingly, CG‐Cu 0.5 ‐DG 10 possessed proper rheological properties predominantly driven strong CG‐H 2 O‐Cu ‐CG hydrogen bonding interaction. Weak DG‐CG only controlled DG initial 4 h, while main force regulating sustained within 48 h. The incorporation MAP further loosened tight crosslinking 10. screened /MAP excellent self‐healing, injectability, antibacterial, anti‐inflammatory, cell proliferation‐promotion activities high biocompatibility. Therefore, expedited wound closure S. aureus ‐infected full‐thickness model lowered necrosis unburned interspaces a rat burn model. results highlight promising translational potential ‐inspired hydrogels burns infected wounds.

Language: Английский

Citations

23
Enhanced Mechanical Strength and Sustained Drug Release in Carrier‐Free Silver‐Coordinated Anthraquinone Natural Antibacterial Anti‐Inflammatory Hydrogel for Infectious Wound Healing DOI

Xiaoliu Liang,

Linyu Ding, Jiaxin Ma

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: May 10, 2024

The persistent challenge of healing infectious wounds and the rise bacterial resistance represent significant hurdles in contemporary medicine. In this study, based on natural small molecule drug Rhein self-assembly to form hydrogels coordinate assembly with silver ions (Ag

Language: Английский

Citations

21
Fe3O4@SiO2/Schiff-base/Zn (II) nanocomposite functioning as a versatile antimicrobial agent against bacterial and fungal pathogens DOI Creative Commons
Sedigheh Azadi, Ali Mohammad Amani, Ali Jangjou

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 17, 2025

Antimicrobial resistance (AMR) presents a critical global health issue, necessitating novel therapeutic strategies to manage bacterial and fungal infections. This study explores the development evaluation of multifunctional Fe3O₄@SiO₂/Schiff-base/Zn (II) magnetic nanocomposite (MNC) with enhanced antimicrobial properties. The synthesized MNC combines characteristics Fe₃O₄ nanoparticles (MNPs) properties Schiff-base ligand functionalized Zn ions. preparation involved coprecipitation Fe₃O₄, coating SiO₂ via modified Stöber method, subsequent functionalization Schiff-base/Zn complex. Comprehensive characterization using FT-IR, XRD, SEM, TEM, DLS, EDX, VSM, TGA confirmed successful synthesis, structural integrity, superparamagnetic behavior MNPs MNC. antifungal antibacterial activities were assessed against six Candida species four strains broth microdilution methods. Fe₃O₄@SiO₂/Schiff-base/Zn exhibited significant inhibitory effects, MIC values 8–64 µg/mL for 64–512 bacteria, demonstrating potent efficacy. MTT assay indicated biocompatibility across various concentrations, except slight cytotoxicity at 256 after five days. To our knowledge, this is first report integrating ligands into achieve versatile platform both biofilm inhibition applications.

Language: Английский

Citations

3
Temperature/pH Co-responsive CS/NIPAM-Based hydrogel with controlled release of Ga3+ for improved infected wound healing DOI

Jibo Diao,

Yingshuang Meng,

Ling‐Feng Wang

et al.

Chemical Engineering Science, Journal Year: 2024, Volume and Issue: 294, P. 120104 - 120104

Published: April 6, 2024

Language: Английский

Citations

12
Polylactic acid films incorporated with nanochitosan, nanocellulose, and Ajwain essential oil: Synthesis, characterizations, with in-vitro and in-vivo antimicrobial properties for infected wound healing DOI Creative Commons
Negin Ehyaeirad, Nima Babolanimogadam,

Masoomeh Dadkhah

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: 7, P. 100425 - 100425

Published: Jan. 7, 2024

Nowadays developing wound dressing with higher antimicrobial properties which is accelerates healing, considered an emerging issue. In this study, we designed polylactic acid (PLA) films incorporated different concentrations of nanochitosan (NCH), nanocellulose (CNC), and Trachyspermum ammi (Ajwain) essential oil (AEO) in-vitro in-vivo properties, for infected healing. AEO was extracted the components were analyzed. The appearance, thickness, release AEO, evaluated used as wounds rats. mechanical selected healing results showed that thymol, P-cymene, γ-terpinene main AEO. Also, all PLA had especially gram-positive bacteria. Finally, 4% NCH 3% highest antibacterial properties. According to obtained in tensile strength test, PLA/NCH good improved films. can be a suitable option new dressings.

Language: Английский

Citations

11
Cornstarch aerogels with thymol, citronellol, carvacrol, and eugenol prepared by supercritical CO2- assisted techniques for potential biomedical applications DOI
Stoja Milovanović, Darka Marković,

Ivona Janković Častvan

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 331, P. 121874 - 121874

Published: Feb. 1, 2024

Language: Английский

Citations

11
CDI crosslinked chitosan/poly (vinyl alcohol) electrospun nanofibers loaded with Achillea millefolium and Viola extract: A promising wound dressing DOI

Milad Ein Marjani,

Romina HMTShirazi,

Toraj Mohammadi

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 336, P. 122117 - 122117

Published: April 3, 2024

Language: Английский

Citations

11
Carboxymethyl chitosan-gelatin based films filled with whey protein-stabilized nanoscale essential oils for skin wound healing: In vivo and in vitro studies DOI
Qiang Peng,

Famin Wen,

Xinrui Tang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141119 - 141119

Published: Feb. 1, 2025

Language: Английский

Citations

1
Enrichment of creatine-gelatin cryogel with Zataria multiflora essential oil and titanium dioxide nanoparticles as a potential wound dressing DOI
Mohammad Hashem Hashempur, Forough Karami,

Mohammad Khoshnam

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 38, P. 102069 - 102069

Published: May 2, 2024

Language: Английский

Citations

8
Incorporation of essential oils in polymeric films for biomedical applications DOI
Joyce Cordeiro Borges, Luís André de Almeida Campos,

Elisângela Afonso Moura Kretzschmar

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 132108 - 132108

Published: May 6, 2024

Language: Английский

Citations

6