Materials Today Bio,
Journal Year:
2024,
Volume and Issue:
29, P. 101361 - 101361
Published: Nov. 22, 2024
Promoting
wound
nerve
regeneration
and
synchronously
initiating
angiogenesis
are
critical
factors
in
the
healing
process
of
diabetic
wounds.
However,
existing
research
on
wounds
mainly
focuses
angiogenesis,
bacterial
infection
reactive
oxygen
species,
often
failing
to
coordinate
neurogenesis
angiogenesis.
To
symbiosis
nerves
blood
vessels
wounds,
we
successfully
designed
a
multifunctional
chitosan
(CS)-based
sponges
by
regulating
structure
CS
specifically
for
healing.
This
sponge,
which
facilitates
effective
exudate
transfer
modulates
microenvironment,
was
constructed
using
hydroxybutyl
grafted
with
thioctic
acid
(TA),
named
as
HCT
sponge.
When
applied
humid
environment,
hydrophobic
side
chains
sponge
interact
self-assembled
domains,
forming
gel-sponge
composite.
Experimental
results
showed
that
adhesion
strength
wet
porcine
skin
70.3
kPa.
Additionally,
exhibited
favorable
degradability,
cytocompatibility
antioxidant
properties.
As
it
is
shown
experiments
vitro,
can
not
only
promote
cell
proliferation,
migration,
vessel
formation,
but
also
M2
macrophage
polarization.
Moreover,
rat
liver
femoral
artery
injury
model
validated
effectively
treat
heavy
bleeding
from
efficacy
through
quickly
sealing
formation
multiple
hemostatic
dams.
In
vivo
studies
indicated
significantly
accelerated
compared
recombinant
bovine
basic
fibroblast
growth
factor
gel,
achieving
better
recovery
after
15
days.
Pathological
show
novel
holds
considerable
promise
treating
wound,
allowing
regenerative
at
site,
provides
significant
potential
further
improving
clinical
applications.
Materials Horizons,
Journal Year:
2024,
Volume and Issue:
11(21), P. 5409 - 5418
Published: Jan. 1, 2024
A
reversible
liquid
gating
membrane
with
the
ability
to
regulate
gas/liquid
transport
is
critical
for
many
fields,
such
as
biological
applications,
multiphase
separation,
and
sewerage
treatment.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(19), P. 2814 - 2814
Published: Oct. 4, 2024
In
this
study,
sodium
alginate
(SA)
aerogel
cross-linked
with
Ca2+
was
selected
as
the
basic
skeleton
to
construct
a
lightweight,
flame
retardant,
and
thermal
insulating
composite
via
modification
melamine
phytic
acid.
The
resulting
aerogel,
SA-1.0
MP,
achieved
conductivity
low
0.0379
W/(m·K).
Compared
pristine
SA
MP
demonstrated
improved
fire
resistance,
evidenced
by
substantial
increase
in
limiting
oxygen
index
(LOI)
from
21.5%
48.8%
V-0
rating
UL-94
test.
Furthermore,
synergistic
mechanism
proposed
explain
its
remarkable
flame-retardant
capability.
Biomaterials Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 1, 2024
Modulation
of
collagen
fibrillogenesis
by
varying
the
degrees
chitosan
deacetylation
for
preparation
co-assembled
biomimetic
fibrils
to
enhance
hemostasis.
