L-arginine modified mesoporous bioactive glass with ROS scavenging and NO release for periodontitis treatment

Bioactive Materials, Journal Year: 2025, Volume and Issue: 48, P. 200 - 216

Published: Feb. 19, 2025

Language: Английский

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Advancing Diabetic Wound Care: The Role of Copper-containing Hydrogels

Heliyon, Journal Year: 2024, Volume and Issue: 10(20), P. e38481 - e38481

Published: Sept. 26, 2024

Language: Английский

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Smart Microneedles in Biomedical Engineering: Harnessing Stimuli‐Responsive Polymers for Novel Applications

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT This review aims to provide a comprehensive analysis of recent advancements in smart microneedles (MNs) within the biomedical field, focusing on integration stimuli‐responsive polymers for enhanced therapeutic and diagnostic applications. Conventional drug delivery methods are known face limitations precision, safety, patient compliance, which can be addressed by innovative features MNs. Through use various polymers, these MNs have been designed react environmental or physiological cues, allowing on‐demand release, biomarker sensing, localized interventions. Fundamental materials used fabrication MNs, including metals, composite hydrogels, reviewed, different categories stimuli‐responsiveness, such as photo, electro, thermal, mechanical, biochemical, explored. Application‐specific designs areas delivery, cancer therapy, diabetes management, skin disease treatments also examined. this discussion, it is highlighted that poised play significant role advancing personalized noninvasive medical treatments.

Language: Английский

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Enzyme memory-driven Ce-enhanced carbon dots from vegetable moss enable rapid treatment of traumatic spinal cord injury

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 505, P. 159097 - 159097

Published: Jan. 7, 2025

Language: Английский

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Improvement of classical therapy in EGFR inhibitors-induced cutaneous adverse reaction by microneedle delivery and Astragalus polysaccharide

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140762 - 140762

Published: Feb. 6, 2025

Language: Английский

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Hybrid hydrogel based on porcine-derived matrix with gallic acid and cerium-doped mesoporous bioactive glass for diabetic wound healing

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113714 - 113714

Published: Feb. 1, 2025

Language: Английский

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The application of traditional Chinese medicine polysaccharides in wound healing: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140993 - 140993

Published: Feb. 12, 2025

Language: Английский

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A sesbania gum/γ-polyglutamic acid photo-crosslinking composite hydrogel loaded with multi-component traditional Chinese medicine extract synergize microenvironment amelioration in infected diabetic wound healing

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140965 - 140965

Published: Feb. 1, 2025

Language: Английский

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Polysaccharides from traditional Chinese medicine and their nano-formulated delivery systems for cancer immunotherapy

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 357, P. 123416 - 123416

Published: Feb. 20, 2025

Language: Английский

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Crosstalk Between H-Type Vascular Endothelial Cells and Macrophages: A Potential Regulator of Bone Homeostasis

Journal of Inflammation Research, Journal Year: 2025, Volume and Issue: Volume 18, P. 2743 - 2765

Published: Feb. 1, 2025

The crosstalk between H-type endothelial cells (ECs) and macrophages is critical for maintaining angiogenesis osteogenesis in bone homeostasis. As core components of type H vessels, ECs respond to various pro-angiogenic signals, forming specialized vascular structures characterized by high expression platelet-endothelial cell adhesion molecule-1 (CD31) mucin (EMCN), thereby facilitating angiogenesis-osteogenesis coupling during formation. Macrophages, as key immune the perivascular region, are primarily classified into classically activated pro-inflammatory M1 phenotype selectively anti-inflammatory M2 phenotype, performing dual functions regulating local tissue homeostasis innate immunity. In recent years, complex vessel has garnered significant interest context bone-related diseases. Orderly regulation immunity provides a new direction preventing metabolic disorders such osteoporosis osteoarthritis. However, their interactions remain insufficiently understood, with limited clinical data available. This review comprehensively examines intricate diverse phenotypes, Insights signaling pathways that regulate crosstalk, focusing on roles osteogenesis. Furthermore, discusses interventions targeting this challenges remain. These insights may offer perspectives provide theoretical foundation developing novel therapeutic strategies.

Language: Английский

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