Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies DOI Creative Commons
Babafemi Laoye, Peter Taiwo Olagbemide,

T. A. Ogunnusi

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 134 - 134

Published: Jan. 27, 2025

Heavy metal contamination has gradually become a very much important significant global issue due to its continual existence in the environment and bioaccumulation ecosystems, posing deleterious risks human health. This review aims investigate sources, pathways, toxicological impacts of heavy metals such as cadmium, lead, mercury, arsenic, elucidating their health consequences plausible mitigation strategies. Furthermore, explores dual origins contamination; natural geological processes anthropogenic activities industrial emissions, mining, agricultural practices. These sip into soil, water, food chains, leading bioaccumulation, bio-magnification causing risks, including cardiovascular diseases, neurological disorders, reproductive toxicity. Additionally, addition indigenous case studies from Nigeria, lead poisoning Zamfara State Great Kwa River Cross Rivers underscores disproportionate impact pollution developing nations. reveal socio-economic environmental dimensions issue, providing contextual understanding region-specific vulnerabilities outcomes. To address these problems, evaluates already existing strategies, chelation therapy phytoremediation, while proposing sustainable, cost-effective solutions for reducing exposure mitigating impacts. It emphasizes importance integrative approaches involving policy, community engagement, technological innovations fight effectively. In conclusion, this seminar contributes toxicity, giving showcasing insights sources implications contamination. By integrating theoretical perspectives with practical solutions, provides robust framework informing policy makers advancing sustainable management practices.

Language: Английский

An insight into the photocatalytic degradation of the antibiotic rifampicin by titanium dioxide nanoparticles in aqueous solution under UV light irradiation DOI

Nurul Amanina A. Suhaimi,

Muhammad Khairul Harisin Umar,

Harry Lik Hock Lau

et al.

Reaction Kinetics Mechanisms and Catalysis, Journal Year: 2024, Volume and Issue: 137(2), P. 1105 - 1123

Published: Jan. 31, 2024

Language: Английский

Citations

8
Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) DOI
Rowida E. Ibrahim,

Mohamed A. Elbealy,

Gamal A. Salem

et al.

Aquatic Toxicology, Journal Year: 2023, Volume and Issue: 261, P. 106630 - 106630

Published: July 2, 2023

Language: Английский

Citations

16
Biochemical Characteristics of Laccases and Their Practical Application in the Removal of Xenobiotics from Water DOI Creative Commons
Agnieszka Gałązka, Urszula Jankiewicz, Andrzej Szczepkowski

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(7), P. 4394 - 4394

Published: March 30, 2023

The rapid growth of the human population in recent decades has resulted intensive development various industries, urban agglomerations and increased production medicines for animals humans, plant protection products fertilizers on an unprecedented scale. Intensive agriculture, expanding areas newly established industrial plants release huge amounts pollutants into environment, which, nature, are very slowly degraded or not decomposed, which leads to their accumulation water terrestrial ecosystems. Researchers scouring extremely contaminated environments identify organisms that have ability degrade resistant xenobiotics, such as PAHs, some pharmaceuticals, plasticizers dyes. These a potential source enzymes could be used bioremediation municipal wastewater. Great hopes pinned oxidoreductases, including laccase, called by green biocatalyst because end product oxidation wide range substrates this enzyme is other compounds, most often dimers, trimers polymers. Laccase immobilization techniques use systems together with adsorption separation found application enzymatic

Language: Английский

Citations

15
The effects of ACE inhibitor Enalapril on Mytilus galloprovincialis: Insights into morphological and functional responses DOI Creative Commons
Mariacristina Filice,

Alessia Caferro,

Daniela Amelio

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 273, P. 107014 - 107014

Published: June 27, 2024

In the last decades, pharmaceuticals have emerged as a new class of environmental contaminants. Antihypertensives, including angiotensin-converting enzyme (ACE) inhibitors, are special concern due to their increased consumption over past years. However, available data on putative effects health aquatic animals, well possible interaction with biological systems still poorly understood. This study analysed whether and which extent exposure Enalapril, an ACE inhibitor commonly used for treating hypertension heart failure, may induce morpho-functional alterations in mussel Mytilus galloprovincialis, sentinel organism water pollution. By mainly focusing digestive gland (DG), target tissue analysing xenobiotics mussels, 10-days 0.6 ng/L (E1) 600 (E2) Enalapril were investigated terms cell viability volume regulation, morphology, oxidative stress, stress protein expression localization. Results indicated that compromised capacity DG cells from E2 group regulate by limiting ability return original after hypoosmotic stress. occurred without significant viability. unaffected also haemocytes viability, although infiltration was histologically observed both groups, suggestive immune response. No changes two experimental groups localization heat shock proteins 70 (HSPs70) HSP90, levels biomarkers. Our results showed that, M. galloprovincialis did not influence status, stress-related proteins, while it activated response face osmotic changes, potential consequences animal performance.

Language: Английский

Citations

5
Photocatalytic degradation of Metformin using TiO2-CuO heterojunctions synthesized by green chemistry and immobilized on beach sand granules in fluidized bed annular photoreactor (FBAP) DOI
Ricardo Solano,

Liset Mallarino,

Miguel Ángel Mueses

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113576 - 113576

Published: July 14, 2024

Language: Английский

Citations

4
Gibberellic acid (GA) induces developmental toxicity in zebrafish (Danio rerio) embryos via oxidative stress DOI
Ying Wei, Yan Gao, Sida Zhang

et al.

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 279, P. 107247 - 107247

Published: Jan. 11, 2025

Language: Английский

Citations

0
Nano‐Biocatalysis for Remediation of Pharmaceutical Micropollutants in Industrial Wastewaters DOI Open Access
Darshankumar Prajapati, Ashish Bhatt,

Ravi Kachhadiya

et al.

Published: March 21, 2025

Language: Английский

Citations

0
Climate Change and Antimicrobial Resistance DOI

Kamal Singh,

Ganesh Chandra Sahoo,

Swati Sharma

et al.

Microorganisms for sustainability, Journal Year: 2025, Volume and Issue: unknown, P. 349 - 361

Published: Jan. 1, 2025

Language: Английский

Citations

0
Benzophenone-3 (oxybenzone) in zebrafish: histopathological and oxidative stress analysis DOI

Alfredo Carvalho,

Ana Clara Rodrigues de Oliveira,

Francisco de Sousa Holanda

et al.

Xenobiotica, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: April 22, 2025

1. Benzophenone-3, commonly known as oxybenzone, is an organic compound widely used in sunscreens and personal care products for protection against UVA UVB rays. Due to its environmental persistence potential toxicity, this study evaluated the effects of BP-3 at environmentally relevant concentration (1 µg/L) on gills, kidney, antioxidant system zebrafish (Danio rerio).2. Adult male were randomly distributed into three groups, each with replicates (n = 10 per group): water control, solvent 1 µg/L BP-3, using a static exposure 96 hours. After experiment, histopathological analyses gills kidneys performed, along biochemical assessments enzymes superoxide dismutase (SOD) catalase (CAT).3. Exposure resulted significant alterations including vascular congestion, epithelial detachment, edema, lamellar aneurysm, indicating severe damage respiratory function. In kidneys, glomerular capillary dilation, tubular cell vacuolization, focal necrosis observed, suggesting renal dysfunction. Biochemical revealed impairment defense system: SOD activity decreased, while CAT remained unchanged, oxidative stress accumulation. significantly increased, enzymatic imbalance cumulative damage.4. These results demonstrate that even low concentrations, induces D. rerio, highlighting compromise organ function defenses. findings underscore need stricter regulation release aquatic environments mitigate ecotoxicological impacts protect biodiversity.

Language: Английский

Citations

0
Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies DOI Creative Commons
Babafemi Laoye, Peter Taiwo Olagbemide,

T. A. Ogunnusi

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 134 - 134

Published: April 24, 2025

Heavy metal contamination has gradually become a highly significant global issue due to its continual existence in the environment and bioaccumulation ecosystems, posing deleterious risks human health. This review aims investigate sources, pathways, toxicological impacts of heavy metals such as cadmium, lead, mercury, arsenic, elucidating their health consequences plausible mitigation strategies. Furthermore, explores dual origins contamination; natural geological processes anthropogenic activities industrial emissions, mining, agricultural practices. These seep into soil, water, food chains, leading bioaccumulation, bio-magnification causing risks, including cardiovascular diseases, neurological disorders, reproductive toxicity. Additionally, addition indigenous case studies from Nigeria, lead poisoning Zamfara State Great Kwa River Cross Rivers underscores disproportionate impact pollution developing nations. reveal socio-economic environmental dimensions issue, providing contextual understanding region-specific vulnerabilities outcomes. To address these problems, evaluates already existing strategies, chelation therapy phytoremediation, while proposing sustainable, cost-effective solutions for reducing exposure mitigating impacts. It emphasizes importance integrative approaches involving policy, community engagement, technological innovations fight effectively. In conclusion, this seminar contributes toxicity, giving showcasing very much important insights sources implications contamination. By integrating theoretical perspectives with practical solutions, provides robust framework informing policy makers advancing sustainable management practices.

Language: Английский

Citations

0