Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: April 25, 2025
Introduction
Phthalates
are
environmental
pollutants
that
harmful
to
human
health.
However,
the
impact
of
phthalate
on
platelet
count
remains
unclear.
This
study
aimed
examine
correlation
between
five
metabolites
in
urine
and
count,
as
well
metabolite
exposure
adults.
Methods
cross-sectional
included
11,409
non-pregnant
participants
aged
>20
years
using
data
available
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2005
2018.
Weighted
logistic
regression,
restricted
cubic
spline
(RCS)
modeling,
weighted
quantile
sum
(WQS)
were
employed
investigate
effects
mono-(carboxyisononyl)
(MCNP),
mono-(carboxyoctyl)
(MCOP),
mono-(3-carboxypropyl)
(MCPP),
mono-isobutyl
(MiBP)
mono-isononyl
(MNP)
count.
Results
Logistic
regression
analysis
suggested
MCOP
[odds
ratio
(OR)
(95%
confidence
interval
CI)
=
0.009
(0.002–0.036)]
was
significantly
associated
with
Subgroup
showed
negative
correlations
across
all
age
sex
groups,
MCNP
[OR
0.083(0.013–0.552)]
displayed
a
association
females.
had
nonlinear
relationship
RCS
model.
WQS
also
revealed
related
Conclusion
Higher
urinary
level
lower
Further
investigation
is
necessary
substantiate
these
findings,
considering
shortcomings
NHANES
study.
Ecological Indicators,
Journal Year:
2023,
Volume and Issue:
155, P. 111058 - 111058
Published: Oct. 7, 2023
Microplastics
(MPs),
which
are
small
plastic
particles
measuring
less
than
5
mm
in
size,
have
emerged
as
a
significant
environmental
concern
marine
ecosystems
worldwide.
The
presence
of
MPs
aquatic
environments
has
increased
due
to
the
contributions
from
anthropogenic
and
terrestrial
sources,
raising
concerns
about
their
abundance
organisms.
primarily
originate
photo-degradation
larger
debris
(macroplastics),
with
release
into
environment
often
occurring
through
breakdown
additive
compounds.
ingestion
poses
eco-toxicological
risks
organisms,
causing
damage
gastrointestinal
(GI)
tracts
stomachs
affected
Approximately
80
%
can
be
classified
either
primary
such
those
generated
during
production
skincare
products,
tires,
use
carriers
for
pharmaceutical
or
secondary
sources
resulting
improper
disposal
plastics
near
coastal
areas
water
bodies.
issue
potential
effects
on
ecosystem
demands
attention.
In
conclusion,
this
review
provides
comprehensive
overview
vulnerability
microplastics
environments,
consolidating
current
understanding
distribution,
fate,
ecological
impacts.
It
emphasizes
urgent
need
ongoing
research
proactive
measures
mitigate
long-term
consequences
microplastic
pollution
essential
services
they
provide.
Environmental Health Perspectives,
Journal Year:
2024,
Volume and Issue:
132(4)
Published: April 1, 2024
Global
plastic
use
has
consistently
increased
over
the
past
century
with
several
different
types
of
plastics
now
being
produced.
Much
these
end
up
in
oceans
or
landfills
leading
to
a
substantial
accumulation
environment.
Plastic
debris
slowly
degrades
into
microplastics
(MPs)
that
can
ultimately
be
inhaled
ingested
by
both
animals
and
humans.
A
growing
body
evidence
indicates
MPs
cross
gut
barrier
enter
lymphatic
systemic
circulation
tissues
such
as
lungs,
liver,
kidney,
brain.
The
impacts
mixed
exposure
on
tissue
function
through
metabolism
remains
largely
unexplored.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
918, P. 170568 - 170568
Published: Feb. 2, 2024
Among
personal
care
products,
quaternium-15
is
prominently
featured
as
a
preservative
in
items
such
shampoos,
soaps,
shaving
and
cosmetics.
The
widespread
use
of
these
products
people's
daily
routines
contributes
to
release
into
aquatic
ecosystems.
In
this
context,
the
primary
aim
study
was
assess
physiological
cellular
responses
digestive
gland
gills
Mytilus
galloprovincialis
exposure.
Cell
viability
ability
cells
regulate
their
volume
were
evaluated.
Additionally,
expression
genes
involved
oxidative
stress
response
assessed
further
substantiate
compound's
harmful
effects.
Results
indicated
significant
decrease
both
RVD
(regulatory
decrease)
capacity
when
exposed
hypotonic
solution.
Furthermore,
impairment
cell
function
corroborated
by
modulation
stress-related
gene
expression,
including
SOD,
Cat,
well
Hsp70
CYP4Y1.
Similar
alterations
observed
gills,
reflecting
impaired
functionality
vital
organ
well.
summary,
outcomes
provide
conclusive
evidence
toxicity
quaternium-15.
This
underscores
urgent
need
investigate
toxicological
effects
contaminant
on
ecosystems
emphasises
necessity
limiting
containing
Chemosphere,
Journal Year:
2023,
Volume and Issue:
336, P. 139273 - 139273
Published: June 19, 2023
Due
to
their
uncontrolled
use,
plastics
has
become
an
environmental
concern,
not
only
for
varying
dimension
but
also
the
potential
release
of
substances
such
as
phthalates
(PAEs)
and
non-phthalates
(NPPs)
into
water.
Phthalates
are
most
common
plasticizers
non-phthalate
di
(2-ethylhexyl)
terephthalate
(DEHT)
have
been
lately
found
in
marine
environment.
Mytilus
galloprovincialis
is
a
well-known
bioindicator
aquatic
environments
due
its
ability
accumulate
wide
variety
xenobiotics,
including
plasticizers.
Hence,
aim
this
study
was
evaluate
bioaccumulation
effects
NPP
DEHT
on
M.
galloprovincialis.
To
purpose,
following
exposure
at
1
mg/l
(DEHT1)
100
(DEHT100),
accumulation
tissues
total
lipids
fatty
acid
(FA)
composition,
protein
content,
cell
viability,
recover
volume
changes
biomarkers
oxidative
stress
were
assessed.
Mussels
able
bioaccumulate
tissues,
with
statistically
significant
increase
compared
control
organisms.
Differences
FA
composition
observed
after
exposure,
since
C16:0,
C18:0,
C20:5ω-3
C22:6ω-3
significantly
decreased
from
exposed
groups.
As
result,
SFA,
MUFA
PUFA
affected
DEHT-exposed
Also,
varied
DEHT100-group.
Considering
physiological
responses,
both
groups
lost
return
original
digestive
gland
(DG)
cells.
On
other
hand,
gills
DG
by
exposure.
Overall,
showed
first
time
that
differentially
affect
mussels,
lipid
metabolism,
well
cellular
parameters.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(45), P. 31435 - 31459
Published: Jan. 1, 2023
Micronanoplastics
(MNPs)
interact
with
blood
components,
resulting
in
anemia,
cardiovascular
diseases,
etc.
Research
gaps
include
toxic
impacts
of
real-world
MNPs,
monomers,
co-pollutants
complex,
and
so
on,
emphasizing
the
need
for
more
research.
Journal of Contaminant Hydrology,
Journal Year:
2024,
Volume and Issue:
266, P. 104399 - 104399
Published: July 17, 2024
Improper
disposal
of
household
and
industrial
waste
into
water
bodies
has
transformed
them
de
facto
dumping
grounds.
Plastic
debris,
weathered
on
beaches
degrades
micro-particles
releases
chemical
additives
that
enter
the
water.
Microplastic
contamination
is
documented
globally
in
both
marine
freshwater
environments,
posing
a
significant
threat
to
aquatic
ecosystems.
The
small
size
these
particles
makes
susceptible
ingestion
by
low
trophic
fauna,
trend
expected
escalate.
Ingestion
leads
adverse
effects
like
intestinal
blockages,
alterations
lipid
metabolism,
histopathological
changes
intestine,
contributing
extinction
vulnerable
species
disrupting
ecosystem
balance.
Notably,
microplastics
(MPs)
can
act
as
carriers
for
pathogens,
potentially
causing
impaired
reproductive
activity,
decreased
immunity,
cancer
various
organisms.
Studies
have
identified
seven
principal
sources
MPs,
including
synthetic
textiles
(35%)
tire
abrasion
(28%),
highlighting
human
contribution
this
pollution.
This
review
covers
aspects
microplastic
pollution,
sources,
extraction
methods,
its
profound
impact
Additionally,
it
explores
preventive
measures,
aiming
guide
researchers
selecting
techniques
inspiring
further
investigation
far-reaching
impacts
fostering
effective
solutions
environmental
challenge.
