Environmental Pollution,
Journal Year:
2024,
Volume and Issue:
347, P. 123652 - 123652
Published: March 5, 2024
The
widespread
use
of
synthetic
turf
in
sports
has
raised
health
concerns
due
to
potential
risks
from
nanoplastic
inhalation
or
ingestion.
Our
research
focused
on
detecting
nanoplastics
drainage
water
a
football
field
and
evaluating
the
toxicity
these
materials
after
mechanical
fragmentation.
We
collected
analysed
samples
for
polymer
content
subjected
high-density
polyethylene
(HDPE)
straws
ethylene
propylene
diene
monomer
(EPDM)
granules
used
fields,
breakdown
create
nanoplastics.
results
indicated
presence
trace
amounts
EPDM
samples.
Furthermore,
toxicological
assessment
revealed
that
broken-down
leachate
surface
rubber
exhibited
high
Daphnia
magna,
while
inner
material
no
significant
toxicity.
findings
highlight
urgent
need
future
identify
specific
toxic
agents
granules.
Fishes,
Journal Year:
2024,
Volume and Issue:
9(3), P. 98 - 98
Published: March 5, 2024
In
recent
years,
micro-
and
nanoplastics
(MNPs)
have
represented
an
emerging
threat
for
the
aquatic
environment
due
to
their
persistence
widespread
distribution.
Indeed,
small
size
increased
surface
area
lead
a
high
biological
reactivity,
which
can
be
crucial
health
status
of
biota.
To
date,
several
studies
investigated
lethal
sublethal
endpoints
MNPs,
while
one
main
challenges
is
understand
mechanisms
toxicity
in
comprehensive
manner.
With
this
aim,
field
ecotoxicology
now
benefit
from
-omics
approaches.
This
review
focuses
on
advances
related
use
transcriptomics,
proteomics,
metabolomics
deeply
investigate
molecular
biochemical
responses
organisms,
both
fishes
invertebrates,
pristine
polystyrene
(PS)
MNPs.
The
literature
reviewed
revealed
that
transcriptomics
are
most
frequently
used
-omic
Overall,
taken
into
consideration
shed
light
events
triggered
by
PS
MNPs
at
cellular
levels,
identifying
as
pathways
involved
oxidative
stress,
energy
metabolism,
immune
response,
nervous
system.
Future
should
therefore
focus
integration
multi-omics
approaches
more
understanding
toxicity.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
927, P. 172380 - 172380
Published: April 9, 2024
The
presence
of
nanoplastics
(NPs)
and
microplastics
(MPs)
in
the
environment
is
recognised
as
a
global-scale
problem.
Due
to
their
hydrophobic
nature
large
specific
surface,
NPs
MPs
can
adsorb
other
contaminants,
polycyclic
aromatic
hydrocarbons
(PAHs),
modulate
bioavailability
hazard.
Adult
zebrafish
were
exposed
for
3
21
days
to:
(1)
0.07
mg/L
(50
nm),
(2)
0.05
(4.5
μm),
(3)
with
sorbed
oil
compounds
water
accommodated
fraction
(WAF)
naphthenic
crude
(MPs-WAF),
(4)
benzo(a)pyrene
(MPs-B(a)P),
(5)
5
%
WAF
(6)
μg/L
B(a)P.
Electrodense
particles
resembling
seen
intestine
lumen
close
microvilli.
abundantly
found
lumen,
but
not
internalised
into
tissues.
After
days,
caused
significant
downregulation
cat,
upregulation
gpx1a
sod1,
while
upregulated
cyp1a
increased
prevalence
liver
vacuolisation.
No
histopathological
alteration
was
observed
gills.
In
this
study,
contaminated
did
increase
PAH
levels
results
highlight
potential
differential
impact
plastic
depending
on
size,
making
it
necessary
urgently
address
ecotoxicological
real
environmental
MPs.
Environment International,
Journal Year:
2024,
Volume and Issue:
187, P. 108713 - 108713
Published: May 1, 2024
Nanoplastics
(NPs)
are
increasingly
pervasive
in
the
environment,
raising
concerns
about
their
potential
health
implications,
particularly
within
aquatic
ecosystems.
This
study
investigated
impact
of
polystyrene
nanoparticles
(PSN)
on
zebrafish
liver
metabolism
using
liquid
chromatography
hybrid
quadrupole
time
flight
mass
spectrometry
(LC-QTOF-MS)
based
non-targeted
metabolomics.
Zebrafish
were
exposed
to
50
nm
PSN
for
28
days
at
low
(L-PSN)
and
high
(H-PSN)
concentrations
(0.1
10
mg/L,
respectively)
via
water.
The
results
revealed
significant
alterations
key
metabolic
pathways
exposure
groups.
metabolites
showed
different
responses
with
L-PSN
H-PSN.
A
total
2078
metabolite
features
identified
from
raw
data
obtained
both
positive
negative
ion
modes,
190
deemed
statistically
H-PSN
Disruptions
lipid
metabolism,
inflammation,
oxidative
stress,
DNA
damage,
amino
acid
synthesis
identified.
Notably,
induced
changes
building
blocks,
membrane-associated
biomarkers,
immune-related
metabolites,
while
was
associated
altered
antioxidant
injury.
For
first
time,
found
depolymerized
by
cytochrome
P450
enzymes.
Utilizing
an
analytical
approach
adverse
outcome
pathway
(AOP),
impaired
stress
have
been
as
potentially
conserved
events
(KEs)
exposure.
These
KEs
further
steatosis,
fibrosis
tissue
organ
level.
Ultimately,
this
could
significantly
biological
health.
highlights
PSN-induced
effects
emphasizing
need
a
better
understanding
risks
NPs
contamination
Diversity,
Journal Year:
2024,
Volume and Issue:
16(1), P. 70 - 70
Published: Jan. 21, 2024
Microplastics
have
been
widely
detected
in
the
natural
water
environment,
which
brings
inevitable
risks
to
ecosystem
and
human
health.
However,
understanding
of
potential
impact
microplastics
on
aquatic
animals,
plants,
health
is
still
limited,
technical
methods
control
microplastic
pollution
are
rare.
Hence,
this
paper
summarizes
progress
research
systems
terms
source,
attributes,
distribution
characteristics,
environmental
effects,
prevention
according
relevant
reports
pollution.
It
also
expounds
basic
ways
for
prevention,
control,
treatment
microplastics,
looks
forward
direction
future.
The
results
show
that
abundance
fresh
China
higher
than
other
regions,
but
level
marine
at
middle
level.
Compared
with
countries,
degree
organisms
lower
level,
spatial
heterogeneity
more
obvious.
Through
hydraulic
substitution
degradable
plastic
products,
can
be
greatly
reduced.
This
provide
a
reference
basis
formulation
China.
Environment International,
Journal Year:
2024,
Volume and Issue:
185, P. 108532 - 108532
Published: Feb. 24, 2024
Nanoplastics
(NPs)
continue
to
accumulate
in
global
aquatic
and
terrestrial
systems,
posing
a
potential
threat
human
health
through
the
food
chain
and/or
other
pathways.
Both
vivo
vitro
studies
have
confirmed
that
liver
is
one
of
main
organs
targeted
for
accumulation
NPs
living
organisms.
However,
whether
exposure
induces
size-dependent
disorders
lipid
metabolism
remains
controversial,
reversibility
NPs-induced
hepatotoxicity
largely
unknown.
In
this
study,
effects
long-term
environmentally
relevant
doses
polystyrene
nanoplastics
(PS-NPs)
on
were
investigated
terms
autophagy
lysosomal
mechanisms.
The
findings
indicated
hepatic
was
more
pronounced
mice
exposed
100
nm
PS-NPs
compared
500
PS-NPs.
This
effect
effectively
alleviated
after
50
days
self-recovery
exposure.
Mechanistically,
although
activated
autophagosome
formation
ERK
(mitogen-activated
protein
kinase
1)/mTOR
(mechanistic
target
rapamycin
kinase)
signaling
pathway,
inhibition
Rab7
(RAB7,
member
RAS
oncogene
family),
CTSB
(cathepsin
B),
CTSD
D)
expression
impaired
function,
thereby
blocking
autophagic
flux
contributing
accumulation.
After
termination
exposure,
exocytosis
responsible
clearance
accumulated
lysosomes.
Furthermore,
function
alleviated.
might
be
reason
alleviation
PS-NPs-induced
recovery.
Collectively,
we
demonstrate
first
time
lysosomes
play
dual
role
persistence
induced
by
environmental
NPs,
which
provide
novel
evidence
prevention
intervention
injury
associated
with
