Titanium Dioxide Nanoparticles Negatively Influence Gill Metabolism in Pinctada fucata martensii DOI Creative Commons
Huayao Zou, Fengfeng Li, Lisha Huang

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(12), P. 682 - 682

Published: Dec. 5, 2024

Background: In recent years, titanium dioxide (TiO2) nanoparticles (NPs) have been widely used in various industries due to their favorable chemical properties, and contamination of the environment has attracted much attention, especially aquatic animals. Methods: Therefore, we assessed impact TiO2 NPs (5 mg/L) on marine bivalve, pearl oyster (Pinctada fucata martensii), gill metabolism. Pearl oysters were exposed seawater containing 5 mg/L for 14 days, followed by 7 days recovery untreated seawater. Gill tissues hepatopancreatic sampled 0, 14, 21 experiment named C0, E14, R7, respectively. Results: Metabolomic analysis identified 102 significantly different metabolites (SDMs) gills tissue following exposure (C0 vs. E14). Compared with group E14 had 76 SDMs (such as acetylcholine, itaconic acid, citric taurine) higher concentrations 26 (including L-arginine isobutyryl-L-carnitine) lower concentrations. KEGG (Kyoto Encyclopedia Genes Genomes) showed that these enriched 28 pathways, including glycine, serine, threonine metabolism, neuroactive ligand–receptor interaction, taurine hypotaurine addition, 116 R7 oysters. 74 6-phosphogluconic isocitric acid) 42 uracil, glycerophosphocholine, N-Acetyl-D-glucosamine) The between 25 pentose phosphate pathway, glutathione citrate cycle (TCA cycle). energy metabolism-associated enzymes revealed reduced Ca2+/Mg2+-ATPase, Na+/K+-ATPase, Total-ATPase activities. Conclusions: These findings suggested may inhibit metabolism function hepatopancreas Meanwhile, affect normal functioning immune osmoregulatory functions even lead oxidative stress neurotoxicity. this study provide a reference analyzing bioadaptation bivalves potential negative effects bivalves.

Language: Английский

Nanoenzyme-based sensors for the detection of anti-tumor drugs DOI
Xiaojing Zhang,

Lina Zou,

Hao Liao

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(2)

Published: Jan. 23, 2025

Language: Английский

Citations

0
Transcriptomic analyses of Pinctada fucata martensii responses under stress of titanium dioxide nanoparticles DOI Creative Commons
Fengfeng Li,

Jiaen Liu,

Zixin Gao

et al.

Frontiers in Marine Science, Journal Year: 2024, Volume and Issue: 11

Published: Aug. 23, 2024

Titanium dioxide nanoparticles (TiO 2 -NPs) released into the environment is becoming more prevalent due to their increased usage, marine TiO -NPs contamination escalating concerns in coastal areas. To understand potential impact of on transcript changes pearl oyster ( Pinctada fucata martensii ), transcriptome analysis gill tissues oysters was conducted after 14-day exposure and 7-day brief recovery. A total 911 differentially expressed genes (DEGs) were identified between control group (TC) experimental (TE) exposed -NPs. Gene ontology (GO) analyses DEGs demonstrated substantial enrichments functions related “hydrolase activity”, “oxidoreductase “DNA integration”. The Kyoto Encyclopedia Genes Genomes (KEGG) pathways indicated enrichment several pathways, including “ubiquitin-mediated protein hydrolysis”, “ECM-receptor interactions”, “NOD-like receptor signaling pathway”, “Toll-like receptor”, “FOXO pathway”. This suggests that intensifies oxidative stress apoptosis pearls oysters, leading negative effects such as disrupted homeostasis, decreased biomineralization activity, reduced neuronal excitability, weakened immune response, cellular metabolism. Transcriptome 844 TE recovery (TR), which underwent a period. GO integration”, “obsolete oxidation-reduction process”, “proteolysis”. KEGG “lysine degradation”, “glycine, serine, threonine metabolism”, findings although showed only slight relief 7 days recovery, they continued experience from -NP exposure. Our shed light complex responses offer valuable theoretical insights toxicological oysters.

Language: Английский

Citations

3
Combined effects of TiO2 nanoparticle and fipronil co-exposure on microbiota in mouse intestine DOI

Canyang Wang,

Yanxin Liu,

Yayu He

et al.

Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 192, P. 114931 - 114931

Published: Aug. 12, 2024

Language: Английский

Citations

1
Metabolomic and microbiomic resilience of Hong Kong oysters to dual stressors: Zinc oxide nanoparticles and low salinity DOI
Jie Lu,

Tuo Yao,

Shengli Fu

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 368, P. 143722 - 143722

Published: Nov. 1, 2024

Language: Английский

Citations

1
Titanium Dioxide Nanoparticles Negatively Influence Gill Metabolism in Pinctada fucata martensii DOI Creative Commons
Huayao Zou, Fengfeng Li, Lisha Huang

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(12), P. 682 - 682

Published: Dec. 5, 2024

Background: In recent years, titanium dioxide (TiO2) nanoparticles (NPs) have been widely used in various industries due to their favorable chemical properties, and contamination of the environment has attracted much attention, especially aquatic animals. Methods: Therefore, we assessed impact TiO2 NPs (5 mg/L) on marine bivalve, pearl oyster (Pinctada fucata martensii), gill metabolism. Pearl oysters were exposed seawater containing 5 mg/L for 14 days, followed by 7 days recovery untreated seawater. Gill tissues hepatopancreatic sampled 0, 14, 21 experiment named C0, E14, R7, respectively. Results: Metabolomic analysis identified 102 significantly different metabolites (SDMs) gills tissue following exposure (C0 vs. E14). Compared with group E14 had 76 SDMs (such as acetylcholine, itaconic acid, citric taurine) higher concentrations 26 (including L-arginine isobutyryl-L-carnitine) lower concentrations. KEGG (Kyoto Encyclopedia Genes Genomes) showed that these enriched 28 pathways, including glycine, serine, threonine metabolism, neuroactive ligand–receptor interaction, taurine hypotaurine addition, 116 R7 oysters. 74 6-phosphogluconic isocitric acid) 42 uracil, glycerophosphocholine, N-Acetyl-D-glucosamine) The between 25 pentose phosphate pathway, glutathione citrate cycle (TCA cycle). energy metabolism-associated enzymes revealed reduced Ca2+/Mg2+-ATPase, Na+/K+-ATPase, Total-ATPase activities. Conclusions: These findings suggested may inhibit metabolism function hepatopancreas Meanwhile, affect normal functioning immune osmoregulatory functions even lead oxidative stress neurotoxicity. this study provide a reference analyzing bioadaptation bivalves potential negative effects bivalves.

Language: Английский

Citations

0