ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(21), P. 15997 - 16002
Published: Oct. 16, 2024
A photoexcited palladium-catalyzed synthesis of chiral allenes from alkynes via a sequence isomerization and deracemization is disclosed. This method offers an efficient cost-effective approach to produce wide range with good enantioselectivities yields (up 98% yield 99% ee). The use readily available stable as starting materials simplifies experimental procedures broadens the scope allene synthesis. DBU plays crucial dual role in this reaction effectively facilitate enhance under visible light excitation, both which are vital for success process.
Language: Английский