Dual-mode ultrasensitive detection of acute leukemia gene Pax-5a based on smart DNA programmed dendrimer DOI

Jun Xu,

Weihua Zhao, Yiling Lai

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 272, P. 117111 - 117111

Published: Dec. 29, 2024

Language: Английский

Aptasensors and Advancement in Molecular Recognition Technology DOI Creative Commons

Rajindra Napit,

Satendra Kumar Jaysawal, Rocky Chowdhury

et al.

Advanced Materials Technologies, Journal Year: 2024, Volume and Issue: unknown

Published: July 2, 2024

Abstract Synthetic oligonucleic acids known as aptamers exhibit remarkable selectivity and affinity for target recognition binding. Selected via an iterative process “selective evolution of ligands by exponential enrichment” (SELEX), fold into defined 3D conformations to interact with their targets. The incorporation elements has driven notable progress in biosensors, giving rise the development aptasensors. Here, aptamer discovery various types aptasensors are summarized. fundamental design principles elaborated along superiority compared antibodies. modes employed aptasensors, such structure‐switching design, hybridization chain reaction amplification, enzyme‐assisted recycling, split examined. Further light is shed on diverse landscape adaptability different analytes well potential propel advancements modern biosensor technology. As a nucleic acids‐based platform, poise become next generation sensitive cost‐effective technology shape future molecular biosensing.

Language: Английский

Citations

8
Advances in magnetic affinity-based isolation/detection of exosomes for robust diagnostics DOI Creative Commons

Veronika Solovicová,

Anna Ďatková,

Tomáš Bertók

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(4)

Published: March 5, 2025

The review article provides a short introduction to exosomes with the focus use as disease markers itself (i.e. their concentration or presence of some specific receptors) source biomarkers such proteins and metabolites. In detail, we are discussing various methods exosome isolation main paper is on affinity capture exosomes, since them can be applied sub-populations produced by organs. comprehensive overview magnetic (bio)affinity detection exosomal cargo using different ligands antibodies, DNA aptamers, peptides, glycan-based recognition, transferrin-based approaches, based recognition phospholipids other approaches including electrostatic interactions. in detail key analytical clinical parameters form an extensive table summarising outcomes published last two years (2023-2024). Finally, also conclusions sections pros cons for and/or determination content.

Language: Английский

Citations

1
MXene–AuNCs-based electrochemical aptasensor for ultrasensitive detection of neuron-specific enolase in early lung cancer diagnosis DOI

Xuan Weng,

Guanbo Wang, Hang Zhang

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112732 - 112732

Published: Jan. 1, 2025

Language: Английский

Citations

0
Advances and applications of G-quadruplex in diagnostics DOI

Yitong Chen,

Junjiang Zhang, Lei Su

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112737 - 112737

Published: Jan. 1, 2025

Language: Английский

Citations

0
Creating a Fluorescent “AND” Logic Gate Aptamer Platform for Identifying Exosomes Derived from Breast Cancer Subtypes DOI
Yifan Liu, Feiran Liu, Zichun Li

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112683 - 112683

Published: Jan. 1, 2025

Language: Английский

Citations

0
H9N2 avian influenza virus diagnostics utilizing specific high-sensitivity enzymatic molecular system termed RPA-based CRISPR-Cas13a DOI
Dalin He,

Saisai Zhao,

Fangfang Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140474 - 140474

Published: Jan. 1, 2025

Language: Английский

Citations

0
Restriction endonuclease-mediated PAM-free CRISPR/Cas12a strategy for one-pot sensitive detection of Escherichia coli O157:H7 DOI

Man Huang,

Yu Zhu, Xin Bing

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160330 - 160330

Published: Feb. 1, 2025

Language: Английский

Citations

0
Hydrogel sensing platforms for monitoring contractility in in vitro cardiac models DOI

Junxiu Lu,

Xiatong Pan, Wenhong Zhang

et al.

Nanoscale, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review summarizes current methods for monitoring cardiomyocyte contractility and explores recent advances in hydrogel-based platforms cell contraction forces. Copyright 2023, Springer Nature; 2019 2022, John Wiley Sons.

Language: Английский

Citations

0
On-demand controlled bidirectional DNAzyme path for ultra-sensitive heavy metal ion detection DOI Creative Commons
Jing Xu, Yujin Li,

Futing Wang

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A bidirectional self-powered biosensor is constructed for the quasi-simultaneous detection of Pb

Language: Английский

Citations

2
Dual-mode ultrasensitive detection of acute leukemia gene Pax-5a based on smart DNA programmed dendrimer DOI

Jun Xu,

Weihua Zhao, Yiling Lai

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 272, P. 117111 - 117111

Published: Dec. 29, 2024

Language: Английский

Citations

0