Fluorescent carbon dots for discriminating cell types: a review DOI
Yongsu An, Zihao Wang, Fu‐Gen Wu

et al.

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(17), P. 3945 - 3962

Published: June 18, 2024

Language: Английский

Ratiometric fluorescent sensing of pyrophosphate with sp³-functionalized single-walled carbon nanotubes DOI Creative Commons
Simon Settele, C. Alexander Schrage, Sebastian Jung

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Jan. 24, 2024

Inorganic pyrophosphate is a key molecule in many biological processes from DNA synthesis to cell metabolism. Here we introduce sp$^{3}$-functionalized (6,5) single-walled carbon nanotubes (SWNTs) with red-shifted defect emission as near-infrared luminescent probes for the optical detection and quantification of inorganic pyrophosphate. The sensing scheme based on immobilization Cu$^{2+}$ ions SWNT surface promoted by coordination covalently attached aryl alkyne groups triazole complex. presence causes fluorescence quenching via photoinduced electron transfer, which reversed copper-complexing analytes such differences response sp$^{3}$-defect pristine nanotube enables reproducible ratiometric measurements wide concentration window. Biocompatible, phospholipid-polyethylene glycol-coated SWNTs sp$^{3}$ defects are employed lysate monitoring progress polymerase chain reaction. This robust probe may serve starting point rational design nanotube-based biosensors.

Language: Английский

Citations

19
Customized Controllable Pyrophosphate Nanosensor Based on Lanthanide Metal–Organic Frameworks for Accurate and Sensitive Detection of Nucleic Acids DOI
Long Yu, Yumin Feng,

Qianqian Yuan

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Pyrophosphate (PPi) and nucleic acid amplification play a critical role in medical diagnostics, making the development of precise nanosensors essential. Lanthanide metal-organic frameworks (Ln-MOFs) are increasingly recognized for their potential advanced luminescent biosensing applications. However, research on customized controllable responses Ln-MOF is still lacking, which molecular-level modular design. In this work, we introduce ligand engineering strategy to regulate coordination-induced antenna effect emission Ln-MOFs, optimizing pyrophosphate sensing from fluorescence turn-off turn-on modes. By tuning coordination environment through programming, discovered "near compensation" effect, allowing transitions between aggregation-induced quenching (AIE/AIQ). This reversible response was supported by density functional theory calculations. Using Eu3+/Tb3+ dual-emission designed with 2,6-pyridinedicarboxylic as optimized ligand, developed self-correcting PPi nanosensor detection limit 0.2 μM. Moreover, system enabled ultrasensitive detection, achieving (LOD) low 1 fM, applications DNA pyrosequencing, qPCR, epigenetic modification (5-formylcytosine) analysis. These findings shed light structural photophysical factors controlling luminescence, offering promising platform highly accurate sensitive biomedical diagnostics.

Language: Английский

Citations

1
A benzimidazole-based new fluorogenic differential/sequential chemosensor for Cu2+, Zn2+, CN-, P2O74-, DNA, its live-cell imaging and pyrosequencing applications DOI
Sellamuthu Anbu, Anup Paul, Kalpana Surendranath

et al.

Sensors and Actuators B Chemical, Journal Year: 2021, Volume and Issue: 337, P. 129785 - 129785

Published: March 18, 2021

Language: Английский

Citations

47
Lanthanide based inorganic phosphates and biological nucleotides sensor DOI
Jashobanta Sahoo, Chidharth Krishnaraj, Jiamin Sun

et al.

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 466, P. 214583 - 214583

Published: May 13, 2022

Language: Английский

Citations

30
An innovative near-infrared fluorescent probe with FRET effect for the continuous detection of Zn2+ and PPi with high sensitivity and selectivity, and its application in bioimaging DOI

Yixuan Yao,

Fudong Zeng,

Jinli Ma

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 309, P. 123837 - 123837

Published: Jan. 2, 2024

Language: Английский

Citations

7
Nanomolar pyrophosphate detection in water using a zinc-terpyridine receptor and its applications in antiproliferative and antioxidant activity DOI
Dipankar Das,

Parnashabari Sarkar,

A.H. Udaya Kumar

et al.

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2023, Volume and Issue: 441, P. 114726 - 114726

Published: March 28, 2023

Language: Английский

Citations

14
Al3+ induced hydrolysis of anthraquinone-based Schiff base fluorescent probe for determination PPi ions and bioimaging DOI
Chen Zhao, Muhammad Asif, Wenjing Lu

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 400, P. 124507 - 124507

Published: March 17, 2024

Language: Английский

Citations

6
Heterocyclic Effect Boosted Peroxidase-like Activity of MIL(Fe) Metal-Organic Framework for Colorimetric Assay and Dye Removal DOI

Dejie Ma,

Na Li, Dangqiang Zhu

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136148 - 136148

Published: Oct. 11, 2024

Language: Английский

Citations

6
Pyridinaldehyde modified luminescence metal-organic framework for highly sensitive and selective fluorescence detection of pyrophosphate DOI

Qingya Yu,

Yu Peng, Qi Cao

et al.

Sensors and Actuators B Chemical, Journal Year: 2022, Volume and Issue: 365, P. 131949 - 131949

Published: April 26, 2022

Language: Английский

Citations

21
Anthraquinone-metal complex fluorescence sensing platform for monitoring PPi mediated by Al3+ and bioimaging DOI
Chen Zhao, Hongmei Xu, Xiaoran Zhang

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1308, P. 138022 - 138022

Published: March 11, 2024

Language: Английский

Citations

4