Research progress on carbon materials in tumor photothermal therapy DOI Open Access
Kezhen Qi, Bin Sun, Shuyuan Liu

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2023, Volume and Issue: 165, P. 115070 - 115070

Published: June 28, 2023

At present, cancer remains one of the leading causes human death worldwide, and surgery, radiotherapy chemotherapy are still main methods treatment. However, these treatments have their drawbacks. Surgical treatment often struggles with complete removal tumor tissue, to a high risk recurrence. Additionally, drugs significant impact on overall health can easily result in drug resistance. The mortality other reasons promote scientific researchers unremittingly develop find more accurate faster diagnosis strategy effective method. Photothermal therapy, which utilizes near-infrared light, offers deeper tissue penetration minimal damage surrounding healthy tissues. Compared conventional methods, photothermal therapy boasts several advantages, including efficiency, non-invasiveness, simplicity, toxicity, fewer side effects. nanomaterials be categorized as either organic or inorganic materials. This review primarily focuses behavior carbon materials role Furthermore, challenges faced by discussed.

Language: Английский

Photothermal Nanomaterials: A Powerful Light-to-Heat Converter DOI Creative Commons
Ximin Cui, Qifeng Ruan, Xiaolu Zhuo

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(11), P. 6891 - 6952

Published: May 3, 2023

All forms of energy follow the law conservation energy, by which they can be neither created nor destroyed. Light-to-heat conversion as a traditional yet constantly evolving means converting light into thermal has been enduring appeal to researchers and public. With continuous development advanced nanotechnologies, variety photothermal nanomaterials have endowed with excellent harvesting capabilities for exploring fascinating prospective applications. Herein we review latest progresses on nanomaterials, focus their underlying mechanisms powerful light-to-heat converters. We present an extensive catalogue nanostructured materials, including metallic/semiconductor structures, carbon organic polymers, two-dimensional materials. The proper material selection rational structural design improving performance are then discussed. also provide representative overview techniques probing photothermally generated heat at nanoscale. finally recent significant developments applications give brief outlook current challenges future directions nanomaterials.

Language: Английский

Citations

799

The light of carbon dots: From mechanism to applications DOI
Boyang Wang, Siyu Lu

Matter, Journal Year: 2022, Volume and Issue: 5(1), P. 110 - 149

Published: Jan. 1, 2022

Language: Английский

Citations

649

The synthetic strategies, photoluminescence mechanisms and promising applications of carbon dots: Current state and future perspective DOI
Chuang He,

Peng Xu,

Xuanhan Zhang

et al.

Carbon, Journal Year: 2021, Volume and Issue: 186, P. 91 - 127

Published: Oct. 11, 2021

Language: Английский

Citations

274

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review DOI Creative Commons
Boyang Wang,

Huijuan Cai,

Geoffrey I. N. Waterhouse

et al.

Small Science, Journal Year: 2022, Volume and Issue: 2(6)

Published: May 8, 2022

Carbon dots (CDs), comprising crystalline graphitized carbon cores and polymer surface groups, are currently attracting a lot of interest in biological fields owing to their fluorescent properties, high photostability, biocompatibility low toxicity. In addition, the easy preparation functionalization CDs stimulate development CDs‐based composite materials with specific functions. Presently, applications growing at remarkable speed, justifying need for up‐to‐date review articles that capture recent progress this blossoming field. review, breakthroughs synthesis, modification, optical toxicology biocatalytic platforms described. Further, research related bioimaging, biosensing, drug delivery, antibacterial, anticancer (photothermal therapy, photodynamic therapy synergistic therapy) antiviral therapies involving discussed detail. Finally, perspective on prospects challenges biomedicine biotechnology is provided.

Language: Английский

Citations

237

Carbon quantum dots: Preparation, optical properties, and biomedical applications DOI Creative Commons
Haili Yang,

Lifei Bai,

Zhirong Geng

et al.

Materials Today Advances, Journal Year: 2023, Volume and Issue: 18, P. 100376 - 100376

Published: May 3, 2023

As an excellent fluorescent nanomaterial, carbon quantum dots (CQDs) have the properties of small molecular weight, particle size, high fluorescence stability, no optical flicker, wide excitation spectrum, continuous, long adjustable emission wavelength, good biocompatibility and low toxicity. At present, it has been widely used in biological detection, vivo vitro imaging, drug delivery diagnostic drugs. This review presents a broad overview recent progress synthesis, properties, biomedical applications CQDs. The synthesis methods CQDs are first introduced, followed by extensive discussion its purification, surface functionalization stability. Furthermore, presented, with emphasis on photoluminescence mechanism relationship between conditions properties. review's much focus is given to CQDs, including imaging (in imaging) (targeted therapy, photodynamic photothermal immunological gene therapy). Finally, we cover key issues future prospects/advances that still deal sector as well possible solutions.

Language: Английский

Citations

167

The Emerging Development of Multicolor Carbon Dots DOI
Jiurong Li, Xiao Gong

Small, Journal Year: 2022, Volume and Issue: 18(51)

Published: Nov. 3, 2022

Abstract As a relatively new type of fluorescent carbon‐based nanomaterials, multicolor carbon dots (MCDs) have attracted much attention because their excellent biocompatibility, tunable photoluminescence (PL), high quantum yield, and unique electronic physicochemical properties. The emission characteristics (CDs) obviously depend on the source precursor, reaction conditions, environment, which directly or indirectly determines CDs. Therefore, this review is first systematic classification summary multiple regulation methods synthetic MCDs reviews recent research progress in synthesis from variety precursor materials such as aromatic molecules, small organic natural biomass, focusing how different produce corresponding MCDs. This also introduces innovative applications fields biological imaging, light‐emitting diodes (LEDs), sensing, anti‐counterfeiting due to PL It hoped that by selecting appropriate adjustment methods, can inspire guide future design tailored MCDs, provide help for development multifunctional

Language: Английский

Citations

165

Carbon dots: mysterious past, vibrant present, and expansive future DOI
Boyang Wang, Geoffrey I. N. Waterhouse, Siyu Lu

et al.

Trends in Chemistry, Journal Year: 2022, Volume and Issue: 5(1), P. 76 - 87

Published: Nov. 10, 2022

Language: Английский

Citations

163

Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging DOI
Zheng Yang, Tiantian Xu, Hui Li

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(18), P. 11047 - 11136

Published: Sept. 7, 2023

Advances in nanotechnology and nanomaterials have attracted considerable interest play key roles scientific innovations diverse fields. In particular, increased attention has been focused on carbon-based exhibiting extended structures unique properties. Among these materials, zero-dimensional structures, including fullerenes, carbon nano-onions, nanodiamonds, dots, possess excellent bioaffinities superior fluorescence properties that make suitable for application to environmental biological sensing, imaging, therapeutics. This review provides a systematic overview of the classification structural properties, design principles preparation methods, optical sensing applications nanomaterials. Recent interesting breakthroughs sensitive selective imaging heavy metal pollutants, hazardous substances, bioactive molecules as well information encryption, super-resolution photoacoustic phototherapy nanomedicine delivery are main focus this review. Finally, future challenges prospects materials highlighted envisaged. presents comprehensive basis directions designing, developing, applying fascinating fluorescent sensors fabricated based specific requirements numerous research

Language: Английский

Citations

123

Aggregation in carbon dots DOI Creative Commons

Yi Ru,

Geoffrey I. N. Waterhouse, Siyu Lu

et al.

Aggregate, Journal Year: 2022, Volume and Issue: 3(6)

Published: Nov. 21, 2022

Abstract Carbon dots (CDs) possess outstanding luminescence properties, making them widely used in optical displays, anti‐counterfeiting systems, bioimaging, and sensors. Presently, there is much debate about the classification of CDs, as well their formation process, structure, fluorescence mechanisms. Aggregation plays an important role (e.g., aggregation‐induced emission) yet seldom studied detail. This review aims fill this knowledge gap, by first exploring how aggregation leads to different types CDs graphene quantum dots, carbon carbonized polymer dots), followed a detailed examination effect morphology on properties application CDs. Finally, opportunities challenges for various applications are discussed, with need better mechanistic understanding being imperative.

Language: Английский

Citations

112

Antibacterial Carbon Dots: Mechanisms, Design, and Applications DOI
Wenbo Zhao, Kai‐Kai Liu, Yong Wang

et al.

Advanced Healthcare Materials, Journal Year: 2023, Volume and Issue: 12(23)

Published: May 13, 2023

Abstract The increase in antibiotic resistance promotes the situation of developing new antibiotics at forefront, while development non‐antibiotic pharmaceuticals is equally significant. In post‐antibiotic era, nanomaterials with high antibacterial efficiency and no drug make them attractive candidates for materials. Carbon dots (CDs), as a kind carbon‐based zero‐dimensional nanomaterial, are attracting much attention their multifunctional properties. abundant surface states, tunable photoexcited excellent photo‐electron transfer properties sterilization CDs feasible gradually emerging field. This review provides comprehensive insights into recent topics include mechanisms, design, optimization processes, potential practical applications also highlighted, such treatment bacterial infections, against biofilms, surfaces, food preservation, bacteria imaging detection. Meanwhile, challenges outlook field discussed proposed.

Language: Английский

Citations

96