Synergizing Pyroelectric Catalysis and Enzyme Catalysis: Establishing a Reciprocal and Synergistic Model to Enhance Anti‐Tumor Activity DOI
Yan Wang, Rui Zhang,

Pengyu Zang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(24)

Published: Feb. 27, 2024

Nanozyme activity is greatly weakened by the microenvironment and multidrug resistance of tumor cells. Hence, a bi-catalytic nanoplatform, which promotes anti-tumor through "charging empowerment" "mutual complementation" processes involved in enzymatic pyroelectric catalysis, loading ultra-small nanoparticles (USNPs) ZnSnO

Language: Английский

Nanoscale mineral as a novel class enzyme mimic (mineralzyme) with total antioxidant capacity detection: Colorimetric and smartphone-based approaches DOI
Azad H. Alshatteri, Sameera Sh. Mohammed Ameen,

Dnya Latif

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102262 - 102262

Published: Aug. 23, 2024

Language: Английский

Citations

14
Au/Pt@ZIF-90 Nanoenzyme Capsule-Based “Explosive” Signal Amplifier for “All-in-Tube” POCT DOI
Wei Liu, Yao Yao, Qi Liu

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(3), P. 1362 - 1370

Published: Jan. 10, 2024

The sensitive, convenient, and visual detection of low-concentration disease markers in biological samples has always been a priority diagnosis. However, existing research problematic due to complex operation unsatisfactory sensitivity. Consequently, an "explosive" signal amplification platform based on Au/Pt@ZIF-90 was developed for sensitive markers. In this study, controllable explosively released Au/Pt nanoparticles (NPs) "nanoenzyme capsule" prepared by encapsulating NPs with excellent peroxidase activity ZIF-90. This achieved adjusting the particle size ZIF-90 encapsulation amount NPs. Using capsules as output module aptamer target recognition module, "All-in-Tube" portable point-of-care (POC) constructed integrating Au/Pt@ZIF-90/filter paper TMB/strips into Eppendorf (EP) tube. By utilizing specific competitive binding targets aptamers, enabled convenient measurement small molecular Taking adenosine proof concept, Moreover, can achieve universal various varying sequence. strategy provides design pattern holds significant potential fields diagnosis environmental monitoring.

Language: Английский

Citations

13
When nanozymes meet enzyme: Unlocking the dual-activity potential of integrated biocomposites DOI
Pravin D. Patil,

Aparna Karvekar,

Sakshi Salokhe

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132357 - 132357

Published: May 19, 2024

Language: Английский

Citations

12
Tailoring the Enzyme-Mimetic Activity and Surface Nanostructure of Metal-Phenolic Platform for Colorimetric Detection of l-Cysteine DOI
Zhiwei Wei, Li Yang,

Minghui Ou

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 12(9), P. 3608 - 3620

Published: Feb. 21, 2024

Green synthesis of multienzyme-like materials with low energy consumption and high economic added value remains challenging; thus, exploring economical environmentally friendly strategies to develop platforms is great significance. Herein, a biomass (polyphenols)-based strategy cost-efficient high-performance (manganese-tannic acid enzyme mimics, TAnc-Mnx-y platforms) multienzyme-mimetic capacities developed via the mineralization metal–phenolic networks (MPNs) in an aqueous solution. This green requires only water as solvent polyphenols metal ions feedstocks no additional supply, making it simple cheap. The process realizes generation MnOx-TA petals, which endows flower-like surface, therefore enhancing surface area pore size. Benefiting from MnOx active sites, enhanced sizes displays exceptional oxidase (OXD)-, peroxidase (POD)-, catalase (CAT)-mimetic activities. Excitingly, could realize fast l-cysteine detection owing their excellent OXD-mimetic activity. Colorimetric studies have shown relatively wide range (8.26–90.86 μM), speed (2 min), significantly limit (2.28 μM) for detection. Moreover, remarkable resistance harsh environments selectivity among other amino acids. In addition, blood experiments also confirm biocompatibility TAnc-Mnx-y. We believe that this study not overcomes current limitation nanoplatforms but provides interesting insights developing sensitive selective methods

Language: Английский

Citations

10
Synergizing Pyroelectric Catalysis and Enzyme Catalysis: Establishing a Reciprocal and Synergistic Model to Enhance Anti‐Tumor Activity DOI
Yan Wang, Rui Zhang,

Pengyu Zang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(24)

Published: Feb. 27, 2024

Nanozyme activity is greatly weakened by the microenvironment and multidrug resistance of tumor cells. Hence, a bi-catalytic nanoplatform, which promotes anti-tumor through "charging empowerment" "mutual complementation" processes involved in enzymatic pyroelectric catalysis, loading ultra-small nanoparticles (USNPs) ZnSnO

Language: Английский

Citations

10