ACS Omega,
Journal Year:
2023,
Volume and Issue:
8(10), P. 8925 - 8935
Published: March 1, 2023
In
recent
years,
mitochondrion
(powerhouse
of
the
cells)
gained
lots
interest
as
one
unorthodox
targets
for
futuristic
cancer
therapy.
As
a
result,
novel
small
molecules
were
developed
to
damage
and
image
mitochondria
in
models.
this
context,
aggregation-induced
emission
probes
(AIEgens)
received
immense
attention
due
their
applications
mitochondria-targeted
biosensing,
imaging,
biomedical
theranostics.
On
other
hand,
phototherapy
(photodynamic
photothermal)
has
emerged
powerful
alternative
manage
its
less
invasive
nature.
However,
merging
these
two
areas
engineer
phototherapeutic
diagnosis
treatment
remained
major
challenge.
mini-review,
we
will
outline
development
molecule
AIEgens
imaging
agents
photosensitizers
photodynamic
therapy
along
with
dual
photodymanic–phototheramal
chemo-photodynamic
We
also
highlight
current
challenges
developing
photothermal
future
theranostic
cancer.
ACS Omega,
Journal Year:
2023,
Volume and Issue:
8(10), P. 8925 - 8935
Published: March 1, 2023
In
recent
years,
mitochondrion
(powerhouse
of
the
cells)
gained
lots
interest
as
one
unorthodox
targets
for
futuristic
cancer
therapy.
As
a
result,
novel
small
molecules
were
developed
to
damage
and
image
mitochondria
in
models.
this
context,
aggregation-induced
emission
probes
(AIEgens)
received
immense
attention
due
their
applications
mitochondria-targeted
biosensing,
imaging,
biomedical
theranostics.
On
other
hand,
phototherapy
(photodynamic
photothermal)
has
emerged
powerful
alternative
manage
its
less
invasive
nature.
However,
merging
these
two
areas
engineer
phototherapeutic
diagnosis
treatment
remained
major
challenge.
mini-review,
we
will
outline
development
molecule
AIEgens
imaging
agents
photosensitizers
photodynamic
therapy
along
with
dual
photodymanic–phototheramal
chemo-photodynamic
We
also
highlight
current
challenges
developing
photothermal
future
theranostic
cancer.
