Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
19(12)
Published: April 17, 2024
Abstract
Chemosensing,
an
interdisciplinary
scientific
domain,
plays
a
pivotal
role
ranging
from
environmental
monitoring
to
healthcare
diagnostics
and
(inter)national
security.
Metal‐organic
gels
(MOGs)
are
recognized
for
their
stability,
selectivity,
responsiveness,
making
them
valuable
chemosensing
applications.
Researchers
have
explored
the
development
of
MOGs
based
on
different
metal
ions
ligands,
allowing
tailored
properties
sensitivities,
even
demonstrated
applications
as
portable
sensors
such
paper‐based
test
strips
practical
use.
Herein,
several
studies
related
in
field
via
UV‐visible
or
luminance
along
with
electrochemical
approach
presented.
These
papers
versatile
materials
use
sensing
bio
analytes.
This
review
provides
foundational
understanding
key
concepts,
methodologies,
recent
advancements
this
field,
fostering
community.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(45)
Published: July 19, 2024
Abstract
The
development
of
high‐accuracy
technologies
to
distinguish
the
quite
tiny
concentration
change
tumor
markers
between
negative
and
positive
is
vital
significance
for
early
screening
diagnosis
cancers,
but
still
a
great
challenge
conventional
biosensors
because
their
“gradual”
detection
mode.
Herein,
unique
“leap‐type”
responsive
lanthanide
MOF‐based
biosensor
(designated
as
Tb‐CeMOF‐X)
with
defect‐mediated
redox‐/photo‐activities
developed
precisely
identifying
acid
phosphatase
(ACP),
an
pathological
marker
prostate
cancer
(PCa)
in
serum.
engineered
Tb‐CeMOF‐X
probe
achieves
bursting
switch‐on
luminescence
at
critical
ACP
(9
U
⋅
L
−1
),
while
keeping
silent
below
this
threshold,
undergoing
qualitative
signal
from
“zero”
“one”
indicators
thus
significantly
improving
identification
precision.
Significantly,
such
response
performance
can
be
further
edited
amplified
by
rational
defect
engineering
crystal
structure
improve
accessibility
active
centers,
consequently
maximizing
sensitivity
toward
complex
biological
media.
This
study
proposes
first
paradigm
ultra‐sensitive
differentiation
capability
positive,
provides
potentially
valuable
tool
accurate
PCa.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 25, 2025
As
metabolic
byproducts
and
representative
indicators
of
food
spoilage,
the
monitoring
detection
for
biogenic
amines
(BAs)
are
crucial
but
challenging
quality
assessment.
Here,
a
strategy
is
proposed
by
combining
fluorescent
probe
molecular
engineering
with
portable
platform
integrating
smartphone
deep
convolutional
neural
network
(DCNN).
Four
ratiometric
probes
tunable
intramolecular
charge
transfer
(ICT)
properties
designed
introducing
different
electron-withdrawing
substituents
(-F,
-OCH3,
-Py,
-CN)
to
carbazole.
Notably,
CNCz
exhibits
strongest
ICT
property
superior
sensing
performance,
satisfying
limit
(11
ppb),
rapid
response
(<5
s),
discriminative
bathochromic
shift
(110
nm).
Then,
smartphone-based
fabricated,
which
enables
rapid,
visual,
on-site
quantitative
evaluation
BAs.
Furthermore,
DCNN,
this
achieves
an
impressive
98.5%
accuracy
in
predicting
meat
freshness.
Hereby,
study
not
only
provides
fine-tune
intrinsic
gain
high-performance
also
presents
intelligent
BAs
freshness
high
practical
applicability.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(45)
Published: July 19, 2024
Abstract
The
development
of
high‐accuracy
technologies
to
distinguish
the
quite
tiny
concentration
change
tumor
markers
between
negative
and
positive
is
vital
significance
for
early
screening
diagnosis
cancers,
but
still
a
great
challenge
conventional
biosensors
because
their
“gradual”
detection
mode.
Herein,
unique
“leap‐type”
responsive
lanthanide
MOF‐based
biosensor
(designated
as
Tb‐CeMOF‐X)
with
defect‐mediated
redox‐/photo‐activities
developed
precisely
identifying
acid
phosphatase
(ACP),
an
pathological
marker
prostate
cancer
(PCa)
in
serum.
engineered
Tb‐CeMOF‐X
probe
achieves
bursting
switch‐on
luminescence
at
critical
ACP
(9
U
⋅
L
−1
),
while
keeping
silent
below
this
threshold,
undergoing
qualitative
signal
from
“zero”
“one”
indicators
thus
significantly
improving
identification
precision.
Significantly,
such
response
performance
can
be
further
edited
amplified
by
rational
defect
engineering
crystal
structure
improve
accessibility
active
centers,
consequently
maximizing
sensitivity
toward
complex
biological
media.
This
study
proposes
first
paradigm
ultra‐sensitive
differentiation
capability
positive,
provides
potentially
valuable
tool
accurate
PCa.
Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
19(12)
Published: April 17, 2024
Abstract
Chemosensing,
an
interdisciplinary
scientific
domain,
plays
a
pivotal
role
ranging
from
environmental
monitoring
to
healthcare
diagnostics
and
(inter)national
security.
Metal‐organic
gels
(MOGs)
are
recognized
for
their
stability,
selectivity,
responsiveness,
making
them
valuable
chemosensing
applications.
Researchers
have
explored
the
development
of
MOGs
based
on
different
metal
ions
ligands,
allowing
tailored
properties
sensitivities,
even
demonstrated
applications
as
portable
sensors
such
paper‐based
test
strips
practical
use.
Herein,
several
studies
related
in
field
via
UV‐visible
or
luminance
along
with
electrochemical
approach
presented.
These
papers
versatile
materials
use
sensing
bio
analytes.
This
review
provides
foundational
understanding
key
concepts,
methodologies,
recent
advancements
this
field,
fostering
community.
