Are stimuli-responsive hybrid copolymer nanoparticles the next innovation in tumor drug delivery? DOI Creative Commons
Martin Hrubý

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 4

Published: Dec. 27, 2024

Language: Английский

BODIPY-based nanoparticles for highly efficient photothermal/gas synergistic therapy against drug-resistant bacterial infection DOI
Shuang Song, Na Yang, Muhammad Azhar Hayat Nawaz

et al.

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(41), P. 19628 - 19641

Published: Oct. 24, 2024

Language: Английский

Citations

1
Ruthenium and platinum-based anticancer metallotherapeutics from the perspectives of photodynamic therapy and bioimaging applications DOI

Sowmiya Ganesan,

Angappan Sheela

Chemical Papers, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 26, 2024

Language: Английский

Citations

0
One-Pot Synthesis of Tumor-Targeted Gold-Doped Cu1.92S Plasmonic Nanodots for Enhanced NIR-Triggered, pH-Responsive PTT/PDT/CDT DOI
Neha Mehrotra, Kaushik Pal

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 17(1), P. 408 - 418

Published: Dec. 25, 2024

Copper-based sulfides are attractive candidates for NIR I and II responsive photothermal therapy but often suffer from high hydrophobicity, suboptimal conversion, poor biostability biocompatibility. In the present work, a rapid, one-pot synthesis method was developed to obtain Au-doped Cu1.92S (ACSH NDs) dual plasmonic nanodots. ACSH NDs exhibit excellent peroxidase-like catalytic activity pH-responsive •OH radical generation along with efficient glutathione depletion under tumor microenvironment mimicking conditions. Upon exposure NIR-I laser light, demonstrate conversion efficiency of 47.44% as well significant photodynamic effect through singlet oxygen generation. The in situ hyaluronic acid capping endows nanodots highly selective uptake breast cancer cells both vitro vivo. Simultaneous chemodynamic NIR-triggered photothermal/photodynamic activities result synergistic cell death 98% inhibition single-dose mouse model study. Therefore, show remarkable potential single nanoplatform-actuated drug-free multimodal therapy.

Language: Английский

Citations

0
Are stimuli-responsive hybrid copolymer nanoparticles the next innovation in tumor drug delivery? DOI Creative Commons
Martin Hrubý

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 4

Published: Dec. 27, 2024

Language: Английский

Citations

0