Hydrogel Preparation Methods and Biomaterials for Wound Dressing

Life, Journal Year: 2021, Volume and Issue: 11(10), P. 1016 - 1016

Published: Sept. 27, 2021

Wounds have become one of the causes death worldwide. The metabolic disorder wound microenvironment can lead to a series serious symptoms, especially chronic wounds that bring great pain patients, and there is currently no effective widely used dressing. Therefore, it important develop new multifunctional dressings. Hydrogel an ideal dressing candidate because its 3D structure, good permeability, excellent biocompatibility, ability provide moist environment for repair, which overcomes shortcomings traditional This article first briefly introduces skin healing process, then preparation methods hydrogel dressings characteristics made natural biomaterials synthetic materials are introduced. Finally, development prospects challenges discussed.

Language: Английский

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A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering

Polymers, Journal Year: 2021, Volume and Issue: 13(13), P. 2100 - 2100

Published: June 25, 2021

Photothermal treatment (PTT) is a promising strategy to deal with multidrug-resistant bacteria infection and promote tissue regeneration. Previous studies demonstrated that hyperthermia can effectively inhibit the growth of bacteria, whereas mild heat cell proliferation, further accelerating wound healing bone Especially, hydrogels photothermal properties could achieve remotely controlled drug release. In this review, we introduce agent hybrid in for effect. We also summarize potential mechanisms regarding antibacterial action, angiogenesis, osteogenesis. Furthermore, recent developments regeneration applications are introduced. Finally, future application discussed. Hydrogels effects provide new direction regeneration, review will give reference engineering.

Language: Английский

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Hydrogels and Wound Healing: Current and Future Prospects

Gels, Journal Year: 2024, Volume and Issue: 10(1), P. 43 - 43

Published: Jan. 5, 2024

The care and rehabilitation of acute chronic wounds have a significant social economic impact on patients global health. This burden is primarily due to the adverse effects infections, prolonged recovery, associated treatment costs. Chronic can be treated with variety approaches, which include surgery, negative pressure wound therapy, dressings, hyperbaric oxygen therapy. However, each these strategies has an array limitations. existing dry dressings lack functionality in promoting healing exacerbating pain by adhering wound. Hydrogels, are commonly polymer-based swell water, been proposed as potential remedies their ability provide moist environment that facilitates healing. Their unique composition enables them absorb exudates, exhibit shape adaptability, modified incorporate active compounds such growth factors antibacterial compounds. review provides updated discussion leading natural synthetic hydrogels utilized healing, details latest advancements hydrogel technology, explores alternate approaches this field. Search engines Scopus, PubMed, Science Direct, Web were advances applications over last fifteen years.

Language: Английский

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Natural and Synthetic Polymeric Biomaterials for Application in Wound Management

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(9), P. 455 - 455

Published: Sept. 3, 2023

Biomaterials are at the forefront of future, finding a variety applications in biomedical field, especially wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try heal through series interconnected processes involving several initiators mediators such as cytokines, macrophages, fibroblasts. The combination biopolymers with healing properties may provide opportunities synthesize matrices that stimulate trigger target cell responses crucial process. This review outlines optimal management care required for treatment special focus on biopolymers, drug-delivery systems, nanotechnologies used enhanced applications. Researchers have utilized range techniques produce dressings, leading products different characteristics. Each method comes its unique strengths limitations, which important consider. future trajectory dressing advancement should prioritize economical eco-friendly methodologies, along improving efficacy constituent materials. aim this work is give researchers possibility evaluate proper materials preparation better understand synthesis conditions well most effective bioactive molecules load.

Language: Английский

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Ultra-stretchable and anti-freezing ionic conductive hydrogels as high performance strain sensors and flexible triboelectric nanogenerator in extreme environments

Nano Energy, Journal Year: 2024, Volume and Issue: 126, P. 109633 - 109633

Published: April 21, 2024

Language: Английский

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Application of Electrospun Drug-Loaded Nanofibers in Cancer Therapy

Polymers, Journal Year: 2024, Volume and Issue: 16(4), P. 504 - 504

Published: Feb. 12, 2024

In the 21st century, chemotherapy stands as a primary treatment method for prevalent diseases, yet drug resistance remains pressing challenge. Utilizing electrospinning to support drugs offers sustained and controlled release methods in contrast oral implantable delivery modes, which enable localized of distinct tumor types. Moreover, core–sheath structure bears advantages dual-drug loading: core sheath layers can carry different drugs, facilitating collaborative counter resistance. This approach minimizes patient discomfort associated with multiple-drug administration. Electrospun fibers not only transport but also integrate metal particles targeted compounds, enabling combinations magnetic heat therapies comprehensive cancer treatment. review delves into preparation techniques tailored various cancers, foreseeing their promising roles

Language: Английский

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Medicated tri-layer fibers based on cellulose acetate and polyvinylpyrrolidone for enhanced antibacterial and wound healing properties

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 348, P. 122856 - 122856

Published: Oct. 10, 2024

Language: Английский

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A review of the current state of natural biomaterials in wound healing applications

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: March 27, 2024

Skin, the largest biological organ, consists of three main parts: epidermis, dermis, and subcutaneous tissue. Wounds are abnormal wounds in various forms, such as lacerations, burns, chronic wounds, diabetic acute fractures. The wound healing process is dynamic, complex, lengthy four stages involving cells, macrophages, growth factors. Wound dressing refers to a substance that covers surface prevent infection secondary damage. Biomaterials applied management have advanced significantly. Natural biomaterials increasingly used due their advantages including biomimicry ECM, convenient accessibility, involvement native healing. However, there still limitations low mechanical properties expensive extraction methods. Therefore, combination with synthetic and/or adding bioactive agents has become an option for researchers this field. In present study, natural effect on its direction, type, level will be investigated. Then, different types polysaccharides proteins were selected desirable biomaterials, polymers variable suitable properties, effective additives. following, structure production methods, participation healing, quality control techniques biomaterials-based dressings discussed.

Language: Английский

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Advanced mycelium materials as potential self-growing biomedical scaffolds

Scientific Reports, Journal Year: 2021, Volume and Issue: 11(1)

Published: June 16, 2021

Abstract Mycelia, the vegetative part of fungi, are emerging as avant-garde generation natural, sustainable, and biodegradable materials for a wide range applications. They constituted self-growing interconnected fibrous network elongated cells, their chemical physical properties can be adjusted depending on conditions growth substrate they fed upon. So far, only extracts derivatives from mycelia have been evaluated tested biomedical In this study, entire structures edible fungi Pleurotus ostreatus Ganoderma lucidum presented bio-composites that mimic extracellular matrix human body tissues, ideal tissue engineering bio-scaffolds. To purpose, two mycelial strains inactivated by autoclaving after growth, morphology, cell wall composition, hydrodynamical mechanical features studied. Finally, biocompatibility direct interaction with primary dermal fibroblasts investigated. The findings demonstrate potentiality all-natural low-cost bio-scaffolds, alternative to systems currently in place.

Language: Английский

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An ultrasmall infinite coordination polymer nanomedicine-composited biomimetic hydrogel for programmed dressing-chemo-low level laser combination therapy of burn wounds

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 426, P. 130610 - 130610

Published: June 15, 2021

Language: Английский

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