Cells,
Journal Year:
2024,
Volume and Issue:
13(15), P. 1277 - 1277
Published: July 30, 2024
MicroRNAs
(miRNAs)
are
small,
non-coding
RNAs
that
play
a
crucial
role
in
regulating
gene
expression.
Dysfunction
miRNAs
can
lead
to
various
diseases,
including
cancers,
neurological
disorders,
and
cardiovascular
conditions.
To
date,
approximately
2000
have
been
identified
humans.
These
small
molecules
shown
promise
as
disease
biomarkers
potential
therapeutic
targets.
Therefore,
identifying
miRNA
for
diseases
developing
effective
drug
delivery
systems
essential.
Nanotechnology
offers
promising
new
approaches
addressing
scientific
medical
challenges.
Traditional
detection
methods
include
next-generation
sequencing,
microarrays,
Northern
blotting,
reverse
transcription-quantitative
polymerase
chain
reaction
(RT-qPCR).
serve
an
alternative
blotting
RT-qPCR
detection.
Moreover,
nanomaterials
exhibit
unique
properties
differ
from
larger
counterparts,
enabling
therapeutics
more
effectively
enter
target
cells,
reduce
degradation
the
bloodstream,
be
released
specific
tissues
or
cells.
This
paper
reviews
application
of
nanotechnology
systems.
Given
still
stages,
holds
great
accelerating
development.
Biomaterials Science,
Journal Year:
2022,
Volume and Issue:
10(24), P. 6911 - 6938
Published: Jan. 1, 2022
A
wound
is
defined
as
damage
to
the
integrity
of
biological
tissue,
including
skin,
mucous
membranes,
and
organ
tissues.
The
treatment
these
injuries
an
important
challenge
for
medical
researchers.
Various
materials
have
been
used
healing
dressing
applications
among
which
carbon
nanomaterials
attracted
significant
attention
due
their
remarkable
properties.
In
present
review,
latest
studies
on
application
graphene
oxide
(GO),
reduced
(rGO),
dots
(CDs),
quantum
(CQDs),
nanotubes
(CNTs),
nanofibers
(CNFs),
nanodiamonds
(NDs)
in
are
evaluated.
Also,
a
variety
carbon-based
nanocomposites
with
advantages
such
biocompatibility,
hemocompatibility,
time,
antibacterial
properties,
cell-adhesion,
enhanced
mechanical
permeability
oxygen
has
reported
various
wounds.
Micromachines,
Journal Year:
2022,
Volume and Issue:
13(9), P. 1395 - 1395
Published: Aug. 26, 2022
With
the
development
of
cross-fertilisation
in
various
disciplines,
flexible
wearable
sensing
technologies
have
emerged,
bringing
together
many
such
as
biomedicine,
materials
science,
control
and
communication
technology.
Over
past
few
years,
multiple
types
devices
that
are
widely
used
for
detection
human
physiological
signals
has
proven
strong
biocompatibility
a
great
potential
further
development.
These
include
electronic
skin
patches,
soft
robots,
bio-batteries,
personalised
medical
devices.
In
this
review,
we
present
an
updated
overview
emerging
sensor
biomedical
applications
comprehensive
summary
research
progress
sensors.
First,
describe
selection
fabrication
their
excellent
electrochemical
properties.
We
evaluate
mechanisms
by
which
these
work,
then
categorise
compare
unique
advantages
variety
from
perspective
vitro
vivo
sensing,
well
some
exciting
body.
Finally,
summarise
opportunities
challenges
field
Small,
Journal Year:
2023,
Volume and Issue:
20(3)
Published: Sept. 13, 2023
Abstract
Designing
suitable
nanomaterials
is
an
ideal
strategy
to
enable
early
diagnosis
and
effective
treatment
of
diseases.
Carbon
dots
(CDs)
are
luminescent
carbonaceous
nanoparticles
that
have
attracted
considerable
attention.
Through
facile
synthesis,
they
process
properties
including
tunable
light
emission,
low
toxicity,
energy
transformation,
leading
diverse
applications
as
optically
functional
materials
in
biomedical
fields.
Recently,
their
potentials
been
further
explored,
such
enzyme‐like
activity
ability
promote
osteogenic
differentiation.
refined
synthesizing
strategies
carbon
dots,
a
rich
treasure
trove
for
new
discoveries,
stand
chance
guide
significant
development
applications.
In
this
review,
the
authors
start
with
brief
introduction
CDs.
By
presenting
mechanisms
examples,
focus
on
how
can
be
used
diagnosing
treating
diseases,
bioimaging
failure
tissues
cells,
biosensing
various
pathogenic
factors
biomarkers,
tissue
defect
repair,
anti‐inflammation,
antibacterial
antiviral,
novel
oncology
treatment.
The
application
integrated
follows
closely
behind.
Furthermore,
challenges
future
directions
CDs
discussed.
hope
review
will
provide
critical
perspectives
inspire
discoveries
prompt
advances
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(2), P. 211 - 211
Published: Jan. 31, 2023
Catecholamines,
including
dopamine,
epinephrine,
and
norepinephrine,
are
considered
one
of
the
most
crucial
subgroups
neurotransmitters
in
central
nervous
system
(CNS),
which
they
act
at
brain’s
highest
levels
mental
function
play
key
roles
neurological
disorders.
Accordingly,
analysis
such
catecholamines
biological
samples
has
shown
a
great
interest
clinical
pharmaceutical
importance
toward
early
diagnosis
diseases
as
Epilepsy,
Parkinson,
Alzheimer
diseases.
As
promising
routes
for
real-time
monitoring
catecholamine
neurotransmitters,
optical
electrochemical
biosensors
have
been
widely
adopted
perceived
dramatically
accelerating
development
last
decade.
Therefore,
this
review
aims
to
provide
comprehensive
overview
on
recent
advances
main
challenges
biosensors.
Particular
emphasis
is
given
biosensors,
reviewing
their
sensing
mechanism
unique
characteristics
brought
by
emergence
nanotechnology.
Based
specific
biosensors’
performance
metrics,
multiple
perspectives
therapeutic
use
nanomaterial
future
trends
also
summarized.
Sensing and Bio-Sensing Research,
Journal Year:
2023,
Volume and Issue:
41, P. 100571 - 100571
Published: July 8, 2023
An
effective
and
affordable
technique
for
detecting
a
variety
of
substances
biological,
medical,
environmental
significance
is
electrochemical
sensing
(ECS).
Due
to
their
distinctive
structures
abilities
offer
robust
electrocatalytic
activity
with
little
surface
fouling,
low
cost,
biocompatibility,
simple
electron
transfer
kinetics,
carbon
materials-based
electrodes
like
graphene
(GR)
nanotube
(CNT)
are
frequently
used
the
development
sensors.
Since
GR
has
large
specific
area,
it
can
host
number
biomolecules
still
have
decent
detection
sensitivity.
Along
important
developments
in
synthesis,
purification,
conjugation,
biofunctionalization
GR,
device
integration
technologies
nanofabrication
evolved.
Combinations
aforementioned
characteristics
accelerated
GR-based
sensors
many
critical
bio-analyses.
The
rapid
bioanalyses
better
sensitivity
selectivity
been
facilitated
by
combination
features.
Direct
transport
between
enzyme
active
electrode
region
made
possible
application
GR.
It
easily
construct
execute
on-site
oxidases
dehydrogenases
improved
thanks
excellent
electro-catalytic
activities
on
redox
reaction
hydrogen
peroxide
(H2O2)
nicotinamide
adenine
dinucleotides
(NADH).
GR's
oxidation
NADH,
thiols,
H2O2,
other
interfering
species
occurs
at
potentials,
use
effectively
suppresses
these
species.
two
benefits
clinical
chemistry,
food
quality
control,
wastewater
treatment,
bioprocessing
great
resistance
fouling
selectivity.
ChemPlusChem,
Journal Year:
2023,
Volume and Issue:
88(1)
Published: Jan. 1, 2023
Abstract
Chiral
carbon
dots
(CDs)
are
a
novel
luminescent
zero‐dimensional
carbon‐based
nanomaterial
with
chirality.
They
not
only
have
the
advantages
of
good
biocompatibility,
multi‐color‐emission,
easy
functionalization,
but
also
exhibits
highly
symmetrical
chiral
optical
characteristics,
which
broadens
their
applicability
to
enantioselectivity
some
amino
acids
like
cysteine
and
lysine,
asymmetric
catalysis
as
well
biomedicine
in
gene
expression
antibiosis.
In
addition,
exploration
excited
state
chirality
CDs
has
developed
its
excellent
circularly
polarized
luminescence
(CPL)
properties,
opening
up
new
application
scenario
recognition
light
sources
anti‐counterfeit
printing
information
encryption.
This
review
mainly
focuses
on
mature
synthesis
approaches
CDs,
including
ligand
method
supramolecular
self‐assembly
method,
then
we
consider
emerging
applications
CPL,
biosensing
biological
effect.
Finally,
concluded
perspective
potential
challenges
future
opportunities
such
fascinating
CDs.
