Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics DOI Creative Commons
Jingyu Shi, Yadi Fan, Qin Zhang

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 16, 2025

Abstract The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment monitoring diseases. Photo‐energy conversion‐based nanomaterials have emerged as versatile that utilizes unique properties light activate with high spatial temporal precision. This review provides comprehensive overview recent developments in photo‐energy conversion using nanomaterials, highlighting their applications disease theranostics. discussion begins by exploring fundamental principles including types materials used various light‐triggered mechanisms, such photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered SERS, photodynamic processes. Following this, delves broad spectrum emphasizing role diagnosis major diseases, cancer, neurodegenerative disorders, retinal degeneration, osteoarthritis. Finally, challenges opportunities technologies are discussed, aiming advance personalized medicine.

Language: Английский

Corn-inspired high-density plasmonic metal-organic frameworks microneedles for enhanced SERS detection of acetaminophen DOI
Xin Li, Zhou Shu,

Zhewen Deng

et al.

Talanta, Journal Year: 2024, Volume and Issue: 278, P. 126463 - 126463

Published: June 25, 2024

Language: Английский

Citations

8

Raman Spectroscopy and AI Applications in Cancer Grading: An Overview DOI Creative Commons
Pietro Manganelli Conforti, Gianmarco Lazzini, Paolo Russo

et al.

IEEE Access, Journal Year: 2024, Volume and Issue: 12, P. 54816 - 54852

Published: Jan. 1, 2024

Raman spectroscopy (RS) is a label-free molecular vibrational technique that able to identify the fingerprint of various samples making use inelastic scattering monochromatic light. Because its advantages non-destructive and accurate detection, RS finding more for benign malignant tissues, tumor differentiation, subtype classification, section pathology diagnosis, operating either in vivo or vitro . However, high specificity comes at cost. The acquisition rate low, depth information cannot be directly accessed, sampling area limited. Such limitations can contained if data pre- post-processing methods are combined with current Artificial Intelligence (AI), essentially, Machine Learning (ML) Deep (DL). latter modifying approach cancer diagnosis currently used automate many analyses, it has emerged as promising option improving healthcare accuracy patient outcomes by abiliting prediction diseases tools. In very broad context, applications in oncology include risk assessment, early prognosis estimation, treatment selection based on deep knowledge. application autonomous datasets generated analysis tissues could make rapid stand-alone help pathologists diagnose accuracy. This review describes milestones achieved applying AI-based algorithms analysis, grouped according seven major types cancers (Pancreatic, Breast, Skin, Brain, Prostate, Ovarian Oral cavity). Additionally, provides theoretical foundation tackle both present forthcoming challenges this domain. By exploring achievements discussing relative methodologies, offers recapitulative insights recent ongoing efforts position effective screening tool pathologists. Accordingly, we aim encourage future research endeavors facilitate realization full potential AI grading.

Language: Английский

Citations

6

Review of NIR-responsive ‘‘Smart’’ carriers for photothermal chemotherapy DOI
Abhijit Karmakar, Akshay Silswal, Apurba Lal Koner

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(20), P. 4785 - 4808

Published: Jan. 1, 2024

This review focuses on the versatile applications of near-infrared (NIR)-responsive smart carriers in biomedical applications, particularly drug delivery and photothermal chemotherapy.

Language: Английский

Citations

5

Ratiometric SERS imaging for indication of peroxynitrite fluctuations in diabetic wound healing process DOI
Hui Chen, Shanshan Lin,

Dianqi Zhang

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 470, P. 144024 - 144024

Published: June 9, 2023

Language: Английский

Citations

13

Recyclable magnetic nanoparticles combined with TiO2 enrichment and “Off” to “On” SERS assay for sensitive detection of alkaline phosphatase DOI

Jiansen Lie,

Feili Luo,

Yafang Liu

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 479, P. 147241 - 147241

Published: Nov. 9, 2023

Language: Английский

Citations

13

Designing SERS nanotags for profiling overexpressed surface markers on single cancer cells: A review DOI
Alexandre Verdin, Cédric Malherbe, Gauthier Eppe

et al.

Talanta, Journal Year: 2024, Volume and Issue: 276, P. 126225 - 126225

Published: May 9, 2024

Language: Английский

Citations

4

Tailoring strategies of SERS tags-based sensors for cellular molecules detection and imaging DOI
Yu Li,

Guoyong Jiang,

Yuqi Wan

et al.

Talanta, Journal Year: 2024, Volume and Issue: 276, P. 126283 - 126283

Published: May 21, 2024

Language: Английский

Citations

4

Monacolin-K loaded MIL-100(Fe) metal–organic framework induces ferroptosis on metastatic triple-negative breast cancer DOI

Chien-Hui Yu,

Glemarie C. Hermosa,

An‐Cheng Sun

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 154751 - 154751

Published: Aug. 23, 2024

Language: Английский

Citations

4

Microcapillary-Derived Plasmonic-Enhanced Cluster through the Self-Assembly Process for Breast Cancer Diagnosis DOI
Thanh Mien Nguyen,

Thu M. T. Nguyen,

Sung‐Jo Kim

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Artificial intelligence (AI)-based surface-enhanced Raman scattering (SERS) is a powerful system for cancer diagnosis, leveraging its unique advantages by combining the high sensitivity of SERS technique with advanced classification capabilities provided computing power. While previous studies have yielded significant results through using exosomes, miRNA, and phenotypic biomarkers detecting breast cancer, these methods frequently entail time-consuming complex pretreatment steps, demanding highly skilled handling. Here, we present free-label platform faster sampling without any pretreat blood plasma diagnosis. In this study, cluster structure gold nanoparticles within confines space microcapillary was fabricated to generate close-packing enhancing electromagnetic field large number "hot spot." We demonstrate that our can significantly amplify signal standard chemical detection R6G molecules. Consequently, solution mixed appropriately between collected from participants build hybrid in measurement. With support machine learning model, diagnosis has successfully classified patients normal accuracy 87.5%.

Language: Английский

Citations

0

Plasmonic Nanoparticles: Enhancing Early Breast Cancer Detection Through Biosensors DOI

Mohamed J. Saadh,

Tamara Nazar Saeed,

Karar H. Alfarttoosi

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Language: Английский

Citations

0