Journal of Biomaterials Science Polymer Edition,
Journal Year:
2023,
Volume and Issue:
35(5), P. 675 - 716
Published: Nov. 9, 2023
The
constantly
accelerating
occurrence
of
microbial
infections
and
their
antibiotic
resistance
has
spurred
advancement
in
the
field
material
sciences
guided
development
novel
materials
with
anti-bacterial
properties.
To
address
clinical
exigencies,
choice
should
be
biodegradable,
biocompatible,
able
to
offer
prolonged
antibacterial
effects.
As
an
attractive
option,
hydrogels
have
been
explored
globally
as
a
potent
biomaterial
platform
that
can
furnish
essential
attributes
owing
its
three-dimensional
(3D)
hydrophilic
polymeric
network,
adequate
biocompatibility,
cellular
adhesion.
current
review
focuses
on
utilization
different
antimicrobial
based
sources
(natural
synthetic).
Further,
also
highlights
strategies
for
generation
advantages
disadvantages
applications
biomedical
fields.
Finally,
prospects
hydrogels-based
biomaterials
are
discussed
along
some
key
challenges
encountered
during
translation.
Small,
Journal Year:
2023,
Volume and Issue:
20(5)
Published: Sept. 26, 2023
Abstract
Microbial
infections
based
on
drug‐resistant
pathogenic
organisms
following
surgery
or
trauma
and
uncontrolled
bleeding
are
the
main
causes
of
increased
mortality
from
worldwide.
The
prevalence
pathogens
has
led
to
a
significant
increase
in
medical
costs
poses
great
threat
normal
life
people.
This
is
an
important
issue
field
biomedicine,
emergence
new
antimicrobial
materials
hydrogels
holds
promise
for
solving
this
problem.
Hydrogel
material
with
good
biocompatibility,
water
absorption,
oxygen
permeability,
adhesion,
degradation,
self‐healing,
corrosion
resistance,
controlled
release
drugs
as
well
structural
diversity.
Bacteria‐disturbing
have
applications
direction
surgical
treatment,
wound
dressing,
device
coating,
tissue
engineering.
paper
reviews
classification
hydrogels,
current
status
research,
potential
one
application
analyzes
research
biomedical
five
aspects:
metal‐loaded
drug‐loaded
carbon‐material‐loaded
fixed
activity
biological
provides
outlook
high
activity,
biodegradability,
injectability,
clinical
applicability
future
development
prospects
field.
