Cited by Photothermal therapy and cell imaging tracking of porous silicon nanoparticle by magnesiothermic reduction and surface modification

Carcinomembrane-Camouflaged Perfluorochemical Dual-Layer Nanopolymersomes Bearing Indocyanine Green and Camptothecin Effectuate Targeting Photochemotherapy of Cancer DOI

Yu‐Hsiang Lee,

C. M. Chen

ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Photochemotherapy has been recognized as a promising combinational modality for cancer treatment. However, difficulties such off-target drug delivery, systemic toxicity, and the hypoxic nature of tumor microenvironment remain hindrances to its application. To overcome these challenges, cell membrane camouflaged perfluorooctyl bromide (PFOB) dual-layer nanopolymersomes bearing indocyanine green (ICG) camptothecin (CPT), named MICFNS, were developed in this study, melanoma was exploited model MICFNS manufacture therapeutic Our data showed that able stabilize both ICG CPT nanocarriers can be quickly internalized by B16F10 cells due membrane-mediated homology. Upon NIR irradiation, trigger hyperthermia offer enhanced singlet oxygen production incorporation PFOB. With ≥10/2.5 μM ICG/CPT, + provide comparable

Language: Английский

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A metal-quercetin-histidine co-coordinated nanoparticle enhances cancer photothermal therapy via reshaping immunosuppressive tumor microenvironment DOI

Shaobo Wang,

Shuncheng Yao,

Quanhong Hu

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 499, P. 156027 - 156027

Published: Sept. 20, 2024

Language: Английский

Citations

Biomimetic Metallacage Nanoparticles with Aggregation-Induced Emission for NIR-II Fluorescence Imaging-Guided Synergistic Immuno-Phototherapy of Tumors DOI

Jingpei Zhang,

Wei Ma,

Boyu Yang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 4, 2024

The integration of theranostics, which combines diagnostics with therapeutics, has markedly improved the early detection diseases, precise medication management, and assessment treatment outcomes. In realm oncology, organoplatinum-based supramolecular coordination complexes (SCCs) that can coload therapeutic agents imaging molecules have emerged as promising candidates for multimodal theranostics tumors. To address challenges tumor-targeted delivery SCCs, this study employs a cell membrane cloaking strategy to fabricate biomimetic metallacage nanoparticles (MCNPs) capabilities homologous targeting capabilities. Specifically, photosensitizer molecule (BTTP) containing AIE-active groups was assembled into C-BTTP through Pt-N coordination. This process endows strong NIR-II fluorescence in aggregated state significantly superior ROS generation compared precursor ligand. After being encapsulated F127, MCNPs were further cloaked U87 cancer membranes, creating achieve tumor-targeting Verified by vitro vivo experiments, enable initiate immunotherapy under photothermal photodynamic stimulation, leading synergistic antitumor effects. Furthermore, evaluation immunogenic death dendritic maturation rate tumor-bearing mice confirmed mechanism immunotherapy. provides an innovative enhancing efficiency offering versatile efficient minimally invasive development such represents significant advancement field nanomedicine, potentially transforming personalized targeted therapies.

Language: Английский

Citations

Biological Smart Materials: Materials for Cancer Treatment DOI

Debasish Panda,

Mansi Agarwal,

B.S. Aruna Kumari

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

Photothermal therapy and cell imaging tracking of porous silicon nanoparticle by magnesiothermic reduction and surface modification DOI

Vy Anh Tran, Sang−Wha Lee, Thi Thu Trinh Phan

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102272 - 102272

Published: Aug. 28, 2024

Language: Английский

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