Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 12, 2024
Intestinal
bacterial
infections
have
become
a
significant
threat
to
human
health.
However,
the
current
typical
antibiotic-based
therapies
not
only
contribute
drug
resistance
but
also
disrupt
gut
microbiota
balance,
resulting
in
additional
adverse
effects
on
life
activities.
There
is
an
urgent
need
develop
new
antibacterial
materials
that
selectively
eliminate
pathogenic
bacteria
without
disrupting
beneficial
communities
or
promoting
resistance.
Herein,
we
utilize
quorum
sensing
(QS),
universal
mechanism
for
regulating
community
behavior,
supramolecular
QS
trap
by
encapsulating
cucurbit[7]uril
(CB[7])
1-vinyl-3-pentylimidazolium
bromide
([VPIM]Br)
form
switch
([VPIM]Br⊂CB[7])
through
host–guest
interactions
followed
grafting
it
onto
cell
surfaces
using
atom
transfer
radical
polymerization.
Subsequently,
matched
pathogens
are
recognized
and
aggregated
interbacterial
signals.
Furthermore,
addition
of
amantadine
(AD)
facilitates
release
[VPIM]Br
competitive
binding
CB[7]
[VPIM]Br⊂CB[7]
sterilization.
This
specifically
triggers
self-aggregation
efficient
elimination
bacteria.
The
[VPIM]Br⊂CB[7]-based
can
increase
diversity
abundance
intestinal
microorganisms
mice,
effectively
treating
Escherichia
coli
K88-induced
damage
perturbing
balance.
supramolecular-switched
opens
up
promising
avenue
recognize
eradicate
antibiotic-free
treatment
other
inflammatory
diseases.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 15, 2025
The
high
selectivity
and
reversibility
of
metal
coordination
enable
precise
modulation
the
structural
morphology
supramolecular
assemblies,
which
is
essential
for
development
intelligent
application
functionalized
materials.
In
this
study,
sheet-like
assemblies
(Pyr-O@tQ[14])
constructed
by
twisted
cucurbit[14]urils
(tQ[14])
pyrene
derivatives
(Pyr-O)
through
host-guest
interactions,
exhibit
excellent
optical
properties,
achieves
highly
sensitive
detection
Hg2+
fluorescence
quenching,
with
a
limit
0.177
μM.
A
novel
smart
platform,
compatible
smartphones,
developed
to
enhance
efficiency
practicality
practical
applications.
From
microscopic
perspective,
adjusting
concentration
can
change
Pyr-O@tQ[14]
from
lamellar
square
finally
spherical,
demonstrating
dynamic
control
assembly
structure
in
response
environmental
stimuli.
This
study
not
only
presents
efficient
quantitative
sensing
platform
but
also
highlights
unique
advantages
tQ[14]
constructing
tunable,
responsive
structures,
opening
new
avenues
design
synthesis
advanced
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(36), P. 14490 - 14498
Published: Aug. 26, 2024
Bacterial
infections
have
emerged
as
a
significant
contributor
to
global
mortality
and
morbidity
rates.
Herein,
we
introduce
dual
fluorescence
"turn-on"
supramolecular
sensor
array
composed
of
three
assembled
complexes
(
Journal of Esthetic and Restorative Dentistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 19, 2025
ABSTRACT
Objective
This
systematic
review
evaluates
the
color‐matching
ability
(Δ
E
00
values)
and
chromatic
stability
of
single‐shade
chameleon
dental
resin
composites
in
restorative
dentistry.
Methods
A
comprehensive
search
PubMed,
Scopus,
Web
Science,
Embase,
Cochrane
Library
was
conducted
following
PRISMA
guidelines.
Studies
assessing
color
adaptation
vitro,
clinical
trials,
retrospective
analyses
were
included.
Results
Seven
studies
(four
two
one
study)
reported
Δ
values
within
clinically
acceptable
thresholds
(<
3.3).
Clinical
trials
showed
that
(e.g.,
Omnichroma,
Vittra
APS
Unique)
achieved
comparable
aesthetic
outcomes
to
multi‐shade
over
12–18
months.
Factors
such
as
staining
agents
cavity
depth
influenced
stability,
with
coffee
exposure
causing
most
discoloration.
Bleaching
procedures
induced
minimal
shifts.
Study
heterogeneity
limited
meta‐analysis.
Conclusion
Single‐shade
provide
reliable
streamlining
shade
selection
reducing
time.
However,
susceptibility
restoration
must
be
considered
for
long‐term
success.
Significance
simplify
selection,
chair
time
enhancing
efficiency
clinicians
should
consider
ensure
stability.
