Supramolecular Switching-Enabled Quorum Sensing Trap for Pathogen-Specific Recognition and Eradication to Treat Enteritis DOI
Xiaojie Wu,

Qinggele Borjihan,

Yueying Su

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Intestinal bacterial infections have become a significant threat to human health. However, the current typical antibiotic-based therapies not only contribute drug resistance but also disrupt gut microbiota balance, resulting in additional adverse effects on life activities. There is an urgent need develop new antibacterial materials that selectively eliminate pathogenic bacteria without disrupting beneficial communities or promoting resistance. Herein, we utilize quorum sensing (QS), universal mechanism for regulating community behavior, supramolecular QS trap by encapsulating cucurbit[7]uril (CB[7]) 1-vinyl-3-pentylimidazolium bromide ([VPIM]Br) form switch ([VPIM]Br⊂CB[7]) through host–guest interactions followed grafting it onto cell surfaces using atom transfer radical polymerization. Subsequently, matched pathogens are recognized and aggregated interbacterial signals. Furthermore, addition of amantadine (AD) facilitates release [VPIM]Br competitive binding CB[7] [VPIM]Br⊂CB[7] sterilization. This specifically triggers self-aggregation efficient elimination bacteria. The [VPIM]Br⊂CB[7]-based can increase diversity abundance intestinal microorganisms mice, effectively treating Escherichia coli K88-induced damage perturbing balance. supramolecular-switched opens up promising avenue recognize eradicate antibiotic-free treatment other inflammatory diseases.

Language: Английский

Synergistic Photochromism, Fluorescence Switching, and Photomagnetism of Three Mn(II) Complexes Based on a Thiazolothiazole Extended Viologen Derivative DOI

Bohong Gao,

Xinli Liu, Gang Li

et al.

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Multifunctional photochromic hybrid materials have attracted great attention due to their wide prospects in information storage, molecular switches, and sensors. Herein, three new coordination polymers (CPs) with paramagnetic Mn2+ ions, namely [Mn2(TTVP)(m-BDC)2] (1), [Mn3(TTVP)(p-BDC)3(H2O)2]·0.5H2O (2), [Mn(TTVP)(H2O)4]·(4,4'-BPC)·2H2O (3) been synthesized (TTVP = 2,5-bis(pyridinium-4-yl)thiazolo[5,4-d]thiazole propionate, m-H2BDC isophthalic acid, p-H2BDC terephthalic 4,4'-H2BPC 4,4'-diphenyldicarboxylic acid). Interestingly, under Ultraviolet (UV) light irradiation, these compounds exhibit distinct performances photoinduced electron transfer (PIET) between aromatic carboxylic acids TTVP, as validated by spectroscopic structural analyses. The coloration kinetics final states are finely tuned modulating the number strength of weak interactions donors (EDs) acceptors (EAs). Furthermore, complexes magnetization enhancement at room temperature, while 2 3 reversible fluorescence modulation during coloration-decoloration cycles. introduction photoregulated fluorescent magnetism into PIET presents a promising approach for development multifunctional materials, holding potential range applications.

Language: Английский

Citations

0
High optical contrast, dual-responsive, wearable photochromic fibers for smart textile engineering DOI

Heyu Zhang,

Ji Fan,

Hengyi Cheng

et al.

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: 51, P. 104795 - 104795

Published: July 14, 2024

Language: Английский

Citations

1
Photofluorochromic Organic Supramolecular Compounds for Multiple Dynamic Anticounterfeiting DOI
Hua Yang,

Li Huang,

Yu-An Shen

et al.

Inorganic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(23), P. 8350 - 8358

Published: Jan. 1, 2024

Photofluorochromic materials with highly efficient luminescence and color-changing behaviour displaying multiple dynamic anticounterfeiting secure information encryption.

Language: Английский

Citations

1
Syntheses and Color-Changing Properties of Three PW11M (M = Ni, Cu, and Zn)-Based Viologen Compounds DOI
Xinxin Hao, Tao Liu, Jun Ying

et al.

Crystal Growth & Design, Journal Year: 2024, Volume and Issue: 24(22), P. 9735 - 9742

Published: Nov. 2, 2024

Three POM–viologen compounds were synthesized at a temperature of 120 °C by traditional hydrothermal technique, namely (1-Cby)·(1,1′-Bby)·[(α–PW11O39)NiII(1-Cby)]·7H2O (PW11Ni-BCby), (1-Cby)·(1,1′-Bby)·[(α-PW11O39)CuII(1-Cby)]·6H2O (PW11Cu-BCby), and (1-Cby)2[H5(α-PW11O39)2Zn2II(1-Cby)2]·27H2O (PW11Zn-Cby) (1-Cby·Br = 1-cyclopropylmethyl-4,4′-bipyridinyl-1-ium bromide; 1,1′-Bby·Br 1,1′-bis(cyclopropylmethyl)-4,4′-bipyridine bromide). All three contain PW11M (M Ni, Cu, Zn), transition metal M-substituted monosubstituted Keggin-type structure. These can exhibit variety excellent properties to stimulate discoloration in light, heat, electricity. Moreover, PW11Cu-BCby PW11Zn-Cby be applied inkless erasable printing dual anticounterfeiting applications based on their photochromic behaviors.

Language: Английский

Citations

1
Highly efficient synthesis and photochromic properties of a pentacyclic N-heterocyclic carbonyl-based dithienylethene DOI
Ming Kong,

Fei Meng,

Jing Chen

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 151, P. 155315 - 155315

Published: Sept. 29, 2024

Language: Английский

Citations

0
Supramolecular Switching-Enabled Quorum Sensing Trap for Pathogen-Specific Recognition and Eradication to Treat Enteritis DOI
Xiaojie Wu,

Qinggele Borjihan,

Yueying Su

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Intestinal bacterial infections have become a significant threat to human health. However, the current typical antibiotic-based therapies not only contribute drug resistance but also disrupt gut microbiota balance, resulting in additional adverse effects on life activities. There is an urgent need develop new antibacterial materials that selectively eliminate pathogenic bacteria without disrupting beneficial communities or promoting resistance. Herein, we utilize quorum sensing (QS), universal mechanism for regulating community behavior, supramolecular QS trap by encapsulating cucurbit[7]uril (CB[7]) 1-vinyl-3-pentylimidazolium bromide ([VPIM]Br) form switch ([VPIM]Br⊂CB[7]) through host–guest interactions followed grafting it onto cell surfaces using atom transfer radical polymerization. Subsequently, matched pathogens are recognized and aggregated interbacterial signals. Furthermore, addition of amantadine (AD) facilitates release [VPIM]Br competitive binding CB[7] [VPIM]Br⊂CB[7] sterilization. This specifically triggers self-aggregation efficient elimination bacteria. The [VPIM]Br⊂CB[7]-based can increase diversity abundance intestinal microorganisms mice, effectively treating Escherichia coli K88-induced damage perturbing balance. supramolecular-switched opens up promising avenue recognize eradicate antibiotic-free treatment other inflammatory diseases.

Language: Английский

Citations

0