Acta Biomaterialia, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 24, 2025
Interventional catheters have been widely applied in diagnostics, therapeutics, and other biomedical areas. The complications caused by catheter-related bacterial infection, venous thrombosis, vascular abrasion become the main reasons for failure of interventional therapy. In this study, polyacrylamide/poly(acrylic acid) lubricating copolymer brushes were constructed on surface efficiently resisted adhesion blood components bacteria through hydration electrostatic repulsion effects. are surface-independently various substrates a three-step method. achieve effective lubricating, antiadhesion, antibacterial properties. Particularly, 2PAM/6PAA exhibited most excellent overall performance with 94% reduction coefficient friction, 87.2 78.3% levels bovine serum albumin fibrin, 92.3, 97.1, 93.5% Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli. significantly reduced vitro circulation test, demonstrating its practical application efficacy. Additionally, experiments molecular dynamics simulations used to reveal antiadhesion mechanism brushes. Thus, work show great potential antithrombotic, antibacterial, lubrication modification medical devices contacting blood.
Language: Английский
Citations
3
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 295, P. 139612 - 139612
Published: Jan. 7, 2025
Language: Английский
Citations
1
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 19, 2025
Abstract Friction‐induced energy consumption is a significant global concern, driving researchers to explore advanced lubrication materials. In nature, vital for the life cycle of animals, plants, and humans, playing key roles in movement, predation, decomposition. After billions years evolution, natural exhibits remarkable professionalism, high efficiency, durability, intelligence, offering valuable insights designing This review focuses on mechanisms organisms advancements biomimetic soft matter It begins by summarizing common biological behaviors their underlying mechanisms, followed current design strategies The then outlines development performance these materials based different strategies. Finally, it discusses potential research directions prospects will be resource advancing
Language: Английский
Citations
1
Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102232 - 102232
Published: July 31, 2024
Language: Английский
Citations
7
Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 186, P. 215 - 228
Published: Aug. 5, 2024
Language: Английский
Citations
4
Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 128 - 128
Published: Feb. 10, 2025
Silicone urinary catheters are broadly employed in medical practice. However, they susceptible to inducing catheter-associated tract infections (CAUTIs) due bacterial adherence the catheter's surface, and exhibit a high friction coefficient, which can greatly affect their effectiveness functionality. Thus, development of silicone catheter with antibacterial properties lubricity is strong demand. We hereby developed poly(vinyl acetate) carrier coating load chlorhexidine acetate applied hydrogel primarily composed polyvinylpyrrolidone (PVP) poly(ethylene glycol) diacrylate (PEGDA), was then coated onto cured through thermal curing process could provide lubricity. Subsequently, we analyzed its surface characteristics assessed property, lubricity, cytotoxicity, potential for vaginal irritation. The findings from Fourier transform infrared spectrometer (FTIR), scanning electron microscope (SEM), water contact angle (WCA), inhibition zone measurements, coefficient analysis confirmed successful modification catheter. Additionally, outcomes cytotoxicity irritation assessments demonstrated that dual-function coating-coated outstanding biocompatibility. This study illustrates prepared possess durable thus gives them broad clinical application prospects.
Language: Английский
Citations
0
Advances in Analytical Chemistry, Journal Year: 2025, Volume and Issue: 15(01), P. 61 - 71
Published: Jan. 1, 2025
Language: Английский
Citations
0
ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 3, 2025
Language: Английский
Citations
0
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: April 14, 2025
Medical catheters require lubrication and antimicrobial properties to reduce complications, such as tissue trauma bacterial infections. Coating hydrogel on the catheter surface is a promising strategy; however, it usually faces challenge of weak interfacial adhesion, thus leading coating delamination or fracture failure. Here, waterborne polyurethane (WPU)-triggered bonding strategy was presented construct coatings, which involved two key steps: (i) sticky WPU layer (ii) dip-coating WPU-coated with monomer solution consisting quaternary ammonium chitosan (QCS), sulfobetaine methacrylate (SBMA), N-vinylpyrrolidone (NVP), zinc sulfate heptahydrate (ZnSO4·7H2O) for growing by ultraviolet initiation. The demonstrated tough adhesion performance catheter, strength achieved 536 N/m. Meanwhile, had variable thickness adjusted QCS possessed excellent hydrophilicity (WCA = 24.6°) low friction (COF 0.0357) based formation hydration layer. Furthermore, introduction ZnSO4·7H2O endowed prominent against Escherichia coli (Gram-negative bacteria) Bacillus subtilis (Gram-positive bacteria). This approach paves an avenue fabricating coatings strong interface stability, controllable thickness, lubrication, antibacterial properties.
Language: Английский
Citations
0
Progress in Organic Coatings, Journal Year: 2024, Volume and Issue: 196, P. 108738 - 108738
Published: Aug. 11, 2024
Language: Английский
Citations
3