Biocompatible and stretchable chitosan piezoelectric gel with antibacterial capability and motion monitoring function for Achilles tendon rupture treatment DOI
Zhencheng Xiong,

Beicheng Lin,

Cheng Huang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123149 - 123149

Published: Dec. 13, 2024

Language: Английский

Revolutionizing Medical Implant Fabrication: Advances in Additive Manufacturing of Biomedical Metals DOI Creative Commons
Yu-Hua Li, Deyu Jiang, Rui Zhu

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022002 - 022002

Published: Nov. 14, 2024

Highlights Exploring personalized biomedical metal implants through additive manufacturing (AM). Presenting new load-bearing and biodegradable alloys for implants. Showcasing AI 4D printing advancements in material properties. AM’s roles various medical fields. Highlighting perspectives of implant technology improved patient care.

Language: Английский

Citations

8
A Functionalized 3D‐Printed Ti6Al4V “Cell Climbing Frame” Inspired by Marine Sponges to Recruit and Rejuvenate Autologous BMSCs in Osteoporotic Bone Repair DOI Open Access

Haoyuan Lei,

Hongfu Cao,

Xi Chen

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Abstract Osteoporosis, characterized by low bone mass and high fracture risk, challenges orthopedic implant design. Conventional 3D‐printed Ti6Al4V scaffolds are mechanically robust but suffer from poor regeneration in osteoporotic patients due to stress shielding cellular senescence. In this study, a functionalized “Cell Climbing Frame” is developed, aiming adapt the mechanical microenvironment of osteoporosis, effectively recruit support adhesion growth autologous marrow mesenchymal stem cells (BMSCs), while rejuvenating senescent for improved regeneration. Inspired marine sponges, processing accuracy limitations selective laser melting (SLM) technology broke through innovatively constructing hierarchical porous structure with macropores micropores nested within each other. Results demonstrate that unique scaffold reduces elastic modulus, facilitates blood penetration, enhances cell growth. Further surface functionalization E7 peptides exosomes promotes attraction rejuvenation BMSCs boosts migration, proliferation, osteogenic differentiation vitro. vivo, accelerates repair rats, delaying surrounding loss, enabling multi‐stage osseointegration. This innovation advances regenerative implants repair.

Language: Английский

Citations

1
Mass transport characteristic and biocompatibility of demand-guided structural biomaterials DOI
Yang Zhao, Qianqian Wu,

Linzhi Wu

et al.

Composite Structures, Journal Year: 2025, Volume and Issue: unknown, P. 118848 - 118848

Published: Jan. 1, 2025

Language: Английский

Citations

0
Synergistic Effects of Zn/Fe Dual-Additives on Ca5(Po4)2sio4 Bioceramics: Induced Biomineralization of Scaffolds with Enhanced Osteogenesis for Bone Tissue Engineering DOI
Jiaqi He,

Fanyan Deng,

Ziheng Bu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Synergistic effects of Zn/Fe dual-additives on Ca5(PO4)2SiO4 bioceramics: Induced biomineralization of scaffolds with enhanced osteogenesis for bone tissue engineering DOI
Junyang He,

Fanyan Deng,

Ziheng Bu

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112476 - 112476

Published: April 1, 2025

Language: Английский

Citations

0
Biocompatible and stretchable chitosan piezoelectric gel with antibacterial capability and motion monitoring function for Achilles tendon rupture treatment DOI
Zhencheng Xiong,

Beicheng Lin,

Cheng Huang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 352, P. 123149 - 123149

Published: Dec. 13, 2024

Language: Английский

Citations

0