Recent Advances in Food Safety: Nanostructure-Sensitized Surface-Enhanced Raman Sensing

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1115 - 1115

Published: March 24, 2025

Food safety is directly related to human health and has attracted intense attention all over the world. Surface-enhanced Raman scattering (SERS), as a rapid selective technique, been widely applied in monitoring food safety. SERS substrates, an essential factor for sensing design, greatly influence analytical performance. Currently, nanostructure-based substrates have garnered significant interest due their excellent merits improving sensitivity, specificity, stability, holding great potential accurate of contaminants complex matrices. This review summarizes fundamentals spectroscopy used nanostructures designing platform, including precious metal nanoparticles, metal-organic frameworks, polymers, semiconductors. Moreover, it introduces mechanisms applications enhancing signals hazardous substances, such foodborne bacteria, pesticide veterinary drug residues, additives, illegal adulterants, packaging material contamination. Finally, with continuous progress nanostructure technology improvement technology, its application prospect testing will be broader.

Language: Английский

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An aptamer-integrated conductive microneedle biosensor for real-time transdermal cortisol monitoring

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 157488 - 157488

Published: Nov. 1, 2024

Language: Английский

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CRISPR/Cas-powered “sweet” DNA nano-sponge for highly sensitive detection of pathogen nucleic acid with portable personal glucometer

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160618 - 160618

Published: Feb. 1, 2025

Language: Английский

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Self-protective DNAzyme-based dual-responsive three-way Y-probe for simultaneous determination of multiple pathogenic bacteria

Analytical and Bioanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

Language: Английский

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Structure-switching G-quadruplex: An efficient CRISPR/Cas12a signal reporter for label-free colorimetric biosensing

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 307, P. 142410 - 142410

Published: March 22, 2025

Language: Английский

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Cryogenically Induced Highly Ordered Single-Strand DNA-Modified Magnetic Nanoprobes for Rapid and Ultrasensitive Bioanalysis

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 30, 2025

The development of highly sensitive detection methods for bioanalysis is crucial early disease diagnosis. Electrochemical biosensing technology offers unique advantages in this area due to its rapid response, high sensitivity, and low cost. However, achieving efficient transfer signaling molecules the electrode interface facilitate effective interaction between signal sensing surface remains a critical challenge ultrasensitive electrochemical detection. In study, we discovered that single-stranded DNA-modified magnetic nanoprobes (signal probe A) subjected cryogenic treatment can rapidly form an orderly monolayer at under external field, while phenomenon was not observed with double-stranded B). Building on finding, developed protective complementary strand B) that, upon target molecules, converted into A. This transformation, combined treatment, enables molecules. Using miRNA-21 carcinoembryonic antigen (CEA) as model targets, optimized conditions, limit 3.4 aM 0.28 fg/mL CEA excellent versatility. summary, study introduces efficient, rapid, enzyme-free, environmentally friendly amplification strategy. approach only provides innovative solution but also new insights enhancing molecule–sensor interactions biosensors.

Language: Английский

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Optimization of MXene/PEDOT:PSS nanocomposite for label-free aptasensing of zearalenone

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136785 - 136785

Published: March 1, 2025

Language: Английский

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Dual DNA recycling amplification-assisted CRISPR/Cas12a cleavage for dual-channel ratiometric fluorescence biosensing of kanamycin antibiotic

Analytical and Bioanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Language: Английский

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Advancements in DNAzyme-based biosensors for the detection of hazardous substances in foodstuff: current applications and future perspectives

Critical Reviews in Food Science and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: April 6, 2025

DNAzyme-based biosensors have emerged as a promising tool for ensuring food safety due to their high sensitivity, specificity, and potential rapid, cost-effective detection of hazardous substances. These leverage DNAzymes-catalytically active DNA molecules-to detect range contaminants, including metal ions, fungal toxins, pesticides, pathogens. While show significant advantages over conventional techniques, challenges such nuclease degradation, interference from complex sample matrices, the costs associated with DNAzyme synthesis still hinder widespread application. Recent advancements in stability DNAzymes, immobilization strategies, integration nanomaterials are progressively addressing these limitations, enhancing performance reliability sensors. This review highlights structural catalytic characteristics assesses current applications safety, discusses innovative strategies overcome existing challenges. The continuous evolution biosensors, particularly design device integration, holds great promise future role routine, reliable analysis.

Language: Английский

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A CRISPR/Cas12a mediated click immunoassay catalyzed by in situ formation of clickase for highly sensitive detection of Trichinella spiralis

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117521 - 117521

Published: April 1, 2025

Language: Английский

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