Recent advances in Metal-Organic Framework derived nanocomposites in gas and chemical sensors: a review DOI Creative Commons
Santosh Nandi, Vinayak Adimule, Shankramma S. Kerur

et al.

Sensing Technology, Journal Year: 2024, Volume and Issue: 2(1)

Published: March 3, 2024

Purpose This systematic review aims to elucidate recent developments in MOF-derived nanocomposites for gas and chemical sensors. The goal is explore the potential of MOF-based devices, specifically miniaturized sensors, addressing critical requirements such as sensitivity, selectivity, stability, low power consumption, cost-effectiveness, extended lifetime. It focuses applications ranging from air quality monitoring industrial leaks medical diagnostics.

Language: Английский

Multifunctional MXenes nanocomposite platforms for biosensing and wearable sensor technologies DOI
Ali Mohammad Amani, Hesam Kamyab, Ehsan Vafa

et al.

Advanced Composites and Hybrid Materials, Journal Year: 2024, Volume and Issue: 8(1)

Published: Dec. 20, 2024

Language: Английский

Citations

10

Electrochemical Technology for the Detection of Tau Proteins as a Biomarker of Alzheimer’s Disease in Blood DOI Creative Commons

Jianman Wang,

Xing Lü, Yao He

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 85 - 85

Published: Feb. 4, 2025

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder and significant cause of dementia in elderly individuals, with growing prevalence our aging population. Extracellular amyloid-β peptides (Aβ), intracellular tau proteins, their phosphorylated forms have gained prominence as critical biomarkers for early precise diagnosis AD, correlating progression response to therapy. The high costs invasiveness conventional diagnostic methods, such positron emission tomography (PET) magnetic resonance imaging (MRI), limit suitability large-scale or routine screening. However, electrochemical (EC) analysis methods made progress detection due sensitivity, excellent specificity, portability, cost-effectiveness. This article reviews the EC biosensing technologies, focusing on protein blood (a low-invasive, accessible medium). then discusses various sensing platforms, including fabrication processes, (LOD), clinical potential show role these sensors transformers changing face AD diagnostics.

Language: Английский

Citations

1

Electrochemical Sensors and Biosensors for the Detection of Pharmaceutical Contaminants in Natural Waters—A Comprehensive Review DOI Creative Commons
Alexandra Virginia Bounegru, Ancuța Dinu, Cătălina Iticescu

et al.

Chemosensors, Journal Year: 2025, Volume and Issue: 13(2), P. 65 - 65

Published: Feb. 11, 2025

This review highlights recent advances in the development of electrochemical sensors and biosensors for detecting pharmaceutical contaminants water samples, including surface water, wastewater, bottled water. The electrode modification materials—such as nanomaterials, conductive polymers, eco-friendly nanocomposites—have shown notable improvements sensor sensitivity selectivity, enabling detection various compounds, diclofenac, ibuprofen, antibiotics, hormones. Future research directions suggest use nanocomposites, multiplexed platforms simultaneous contaminant detection, integration into portable devices situ monitoring. Additionally, integrating with specific biomolecules IoT technology can expand their applicability, continuous efficient quality monitoring, thus supporting public health environmental protection.

Language: Английский

Citations

1

Recent advances in wearable electrochemical sensors for in situ detection of biochemical markers DOI Creative Commons
Yanli Jiao, Xinge Yu

Science China Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 14, 2025

Language: Английский

Citations

1

Electrochemical Immunosensors Developed for Amyloid-Beta and Tau Proteins, Leading Biomarkers of Alzheimer’s Disease DOI Creative Commons
Abhinav Sharma, Lúcio Angnes, N. Sattarahmady

et al.

Biosensors, Journal Year: 2023, Volume and Issue: 13(7), P. 742 - 742

Published: July 17, 2023

Alzheimer's disease (AD) is the most common neurological and a serious cause of dementia, which constitutes threat to human health. The clinical evidence has found that extracellular amyloid-beta peptides (Aβ), phosphorylated tau (p-tau), intracellular proteins, are derived from amyloid precursor protein (APP), leading biomarkers for accurate early diagnosis AD due their central role in pathology, correlation with progression, diagnostic value, implications therapeutic interventions. Their detection monitoring contribute significantly understanding advancing care. Available techniques, including magnetic resonance imaging (MRI) positron emission tomography (PET), mainly used validate diagnosis. However, these methods expensive, yield results difficult interpret, have side effects such as headaches, nausea, vomiting. Therefore, researchers focused on developing cost-effective, portable, point-of-care alternative devices detect specific cerebrospinal fluid (CSF) other biofluids. In this review, we summarized recent progress electrochemical immunosensors detecting (Aβ p-tau protein) subtypes (AβO, Aβ(1-40), Aβ(1-42), t-tau, cleaved-tau (c-tau), p-tau181, p-tau231, p-tau381, p-tau441). We also evaluated key characteristics performance developed immunosensing platforms, signal interfaces, nanomaterials or amplifiers, biofunctionalization methods, even primary sensing performances (i.e., sensitivity, linear range, limit (LOD), application).

Language: Английский

Citations

21

Two-dimensional materials and their role in sensitivity enhancement of surface plasmon resonance based biosensor DOI

Abin Philip,

A. Ruban Kumar

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 171, P. 117497 - 117497

Published: Dec. 20, 2023

Language: Английский

Citations

17

Hierarchical Nanobiosensors at the End of the SARS-CoV-2 Pandemic DOI Creative Commons

Jael Abigail Medrano-Lopez,

I. Villalpando, Ma. Isabel Salazar

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(2), P. 108 - 108

Published: Feb. 18, 2024

Nanostructures have played a key role in the development of different techniques to attack severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some applications include masks, vaccines, and biosensors. The latter are great interest for detecting diseases since some their features allowed us find specific markers secretion samples such as saliva, blood, even tears. Herein, we highlight how hierarchical nanoparticles integrated into two or more low-dimensional materials present outstanding advantages that attractive photonic biosensing using nanoscale functions. potential nanohybrids with superlative mechanical characteristics together optical optoelectronic properties is discussed. progress scientific research focused on variety viruses has become medical milestone recent years, laid groundwork future disease treatments. This perspective analyzes crucial information about use nanostructures prevention, treatment, mitigation SARS-CoV-2 effects.

Language: Английский

Citations

8

Biosensors for the Detection of Pathogenic Bacteria: Current Status and Future Perspectives DOI
Yalçın Dicle, Murat Karameşe

Future Microbiology, Journal Year: 2024, Volume and Issue: 19(3), P. 281 - 291

Published: Feb. 1, 2024

Pathogenic microorganisms pose significant threats to human health, food safety and environmental integrity. Rapid accurate detection of these pathogens is essential mitigate their impact. Fast, sensitive methods such as biosensors also play a critical role in preventing outbreaks controlling spread. In recent years, have emerged revolutionary technology for pathogen detection. This review aims present the current developments biosensor technology, investigate by which are used pathogenic bacteria highlight future perspectives on subject.

Language: Английский

Citations

7

Integration of microfluidic chips with biosensors DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu,

Sivarasu Sudesh

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(9)

Published: Aug. 23, 2024

Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.

Language: Английский

Citations

7

Synthesis, Functionalization, and Biomedical Applications of Iron Oxide Nanoparticles (IONPs) DOI Creative Commons
Mostafa Salehirozveh, Parisa Dehghani, Ivan Mijaković

et al.

Journal of Functional Biomaterials, Journal Year: 2024, Volume and Issue: 15(11), P. 340 - 340

Published: Nov. 12, 2024

Iron oxide nanoparticles (IONPs) have garnered significant attention in biomedical applications due to their unique magnetic properties, biocompatibility, and versatility. This review comprehensively examines the synthesis methods, surface functionalization techniques, diverse of IONPs. Various chemical physical including coprecipitation, sol-gel processes, thermal decomposition, hydrothermal synthesis, sonochemical routes, are discussed detail, highlighting advantages limitations. Surface strategies, such as ligand exchange, encapsulation, silanization, explored enhance biocompatibility functionality Special emphasis is placed on role IONPs biosensing technologies, where optical properties enable advancements, surface-enhanced Raman scattering (SERS)-based biosensors, fluorescence field-effect transistor (FET) biosensors. The explores how sensitivity selectivity detecting biomolecules, demonstrating potential for point-of-care diagnostics. Additionally, resonance imaging (MRI), targeted drug delivery, tissue engineering, stem cell tracking discussed. challenges future perspectives clinical translation also addressed, emphasizing need further research optimize ensure safety efficacy medical applications. aims provide a comprehensive understanding current state both broader fields.

Language: Английский

Citations

7