A Comprehensive Review on the Green Synthesis of Nanoparticles: Advancements in Biomedical and Environmental Applications

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Language: Английский

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Advancements in Metal and Metal Oxide Nanoparticles for Targeted Cancer Therapy and Imaging: Mechanisms, Applications, and Safety Concerns

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106622 - 106622

Published: Jan. 1, 2025

Language: Английский

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Revolutionizing Oncology: Iron Oxide Nanoparticles in Cancer Diagnosis and Treatment

International Journal of Scientific Research in Science and Technology, Journal Year: 2025, Volume and Issue: 12(1), P. 161 - 173

Published: Jan. 26, 2025

Iron oxide nanoparticles (IONPs) have emerged as a transformative tool in oncology, offering unprecedented opportunities for early cancer diagnosis and effective treatment. These exhibit unique physicochemical properties, including superparamagnetism, biocompatibility, large surface area-to-volume ratio. properties make them particularly suitable applications such high-resolution imaging, targeted drug delivery, hyperthermia therapy. Additionally, their ability to be functionalized with various biomolecules enables precision targeting of cancerous tissues, further enhancing efficacy. This article delves into the cutting-edge advancements utilization IONPs, examines multifunctional roles addresses challenges clinical translation, outlines future directions research application this dynamic field.

Language: Английский

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Evaluation of ultrasonic energy and temperature on the structural, morphological, and magnetic properties of Fe3O4 nanoparticles

Solid State Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 107880 - 107880

Published: Feb. 1, 2025

Language: Английский

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Next-Gen Point-of-Care Tool for Ultra-Sensitive Detection of Urinary Spermine for Prostate Cancer Diagnosis

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Prostate cancer (PCa), the second most common in men, demands effective early detection strategies. Elevated spermine levels prostate tissue contrast with decreased urinary concentrations PCa patients. Here, we present a novel sensing platform combining differential pulse voltammetry and an extended gate field-effect transistor (EGFET) molecularly imprinted polymer|molecular imprinting (MIP) nanofilm for selective sensitive detection. Key advancements include successfully constructing characterizing pseudoreference electrode precisely engineered analyte binding interface. The Ag/AgCl exhibited high reliability reproducibility, optimized to enhance conductivity minimize interference noises. Electrochemical analysis confirmed successful MIP modification, creating precise 3D-imprinted accurately quantified artificial urine across from 0.1 1000 ng/mL, achieving limit of 1.23 ng/mL. High selectivity was demonstrated against competing polyamines such as spermidine histamine. Analysis electrical properties indicated that induced changes surface potential, altering metal-oxide-semiconductor threshold voltage validating system's sensitivity. superior performance factor (IF ≈ 4.1) sensitivity 10 times higher compared nonimprinted polymers. Hill-Langmuir strong affinity spermine. Clinical validation using human samples diagnostic evaluations consistency liquid chromatography mass spectrometry, exhibiting excellent linear correlation (R2 = 0.97) without statistically significant differences (p-value <0.0001). This study introduces robust, miniaturized, cost-effective EGFET-based sensor detection, offering substantial potential clinical diagnostics biomarker monitoring.

Language: Английский

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Antimicrobial Coatings Based on Hybrid Iron Oxide Nanoparticles

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(9), P. 637 - 637

Published: April 22, 2025

This study presents the preparation of hybrid iron oxide nanocomposites through a two-step process combining microfluidic-assisted synthesis and post-synthetic surface modification. Fe3O4 nanoparticles were synthesized simultaneously functionalized with salicylic acid using three-dimensional vortex-type microfluidic chip, enabling rapid uniform particle formation. The resulting Fe3O4/SA nanostructures further modified either silver or copper to form enhanced antimicrobial functionality. These subsequently integrated into silica aerogel matrices dip-coating approach improve dispersion, structural stability, biocompatibility. morphological properties samples investigated XRD, FT-IR, TEM SAED analysis, Raman microscopy. In vitro cytotoxicity assays demonstrated that Fe3O4/SA–Ag Fe3O4/SA–CuO exhibit potent antibacterial activity cell type-dependent vivo biodistribution studies showed no accumulation in major organs selective clearance via spleen, validating systemic safety platform. findings highlight potential as biocompatible, coatings for advanced biomedical surfaces.

Language: Английский

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Enhanced Detection of Brain-Derived Neurotrophic Factor (BDNF) Using a Reduced Graphene Oxide Field-Effect Transistor Aptasensor

Nanoscale, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Neurodegenerative diseases, characterized by the progressive deterioration of neuronal function and structure, pose significant global public health economic challenges.

Language: Английский

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